3C4T
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![BU of 3c4t by Molmil](/molmil-images/mine/3c4t) | Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer | Descriptor: | CADMIUM ION, Endoribonuclease Dicer | Authors: | Lee, J.K, Du, Z, Tjhen, R.J, Stroud, R.M, James, T.L. | Deposit date: | 2008-01-30 | Release date: | 2008-02-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage. Proc.Natl.Acad.Sci.Usa, 105, 2008
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8QES
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6DXH
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![BU of 6dxh by Molmil](/molmil-images/mine/6dxh) | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with 4-(4-tert-butylphenyl)-4-oxobutanoate | Descriptor: | 4-(4-tert-butylphenyl)-4-oxobutanoic acid, UNKNOWN ATOM OR ION, Ubiquitin carboxyl-terminal hydrolase 5, ... | Authors: | Harding, R.J, Mann, M.K, Ravichandran, M, Ferreira de Freitas, R, Franzoni, I, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Schapira, M, Structural Genomics Consortium (SGC) | Deposit date: | 2018-06-28 | Release date: | 2018-07-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain. J.Med.Chem., 62, 2019
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3CA0
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![BU of 3ca0 by Molmil](/molmil-images/mine/3ca0) | Sambucus nigra agglutinin II (SNA-II), hexagonal crystal form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Agglutinin II, ... | Authors: | Maveyraud, L, Niwa, H, Guillet, V, Palmer, R.A, Reynolds, C.D, Mourey, L. | Deposit date: | 2008-02-19 | Release date: | 2008-11-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for sugar recognition, including the Tn carcinoma antigen, by the lectin SNA-II from Sambucus nigra Proteins, 75, 2009
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1DKL
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3C51
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6DNK
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![BU of 6dnk by Molmil](/molmil-images/mine/6dnk) | Human Stimulator of Interferon Genes | Descriptor: | Stimulator of interferon genes protein, cGAMP | Authors: | Fernandez, D, Li, L, Ergun, S.L. | Deposit date: | 2018-06-06 | Release date: | 2019-03-13 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition. Cell, 178, 2019
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3C5O
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![BU of 3c5o by Molmil](/molmil-images/mine/3c5o) | Crystal structure of the conserved protein of unknown function RPA1785 from Rhodopseudomonas palustris | Descriptor: | GLYCEROL, UPF0311 protein RPA1785 | Authors: | Kim, Y, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-02-01 | Release date: | 2008-02-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Crystal Structure of the Conserved Protein of Unknown Function RPA1785 from Rhodopseudomonas palustris. To be Published
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7RZY
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![BU of 7rzy by Molmil](/molmil-images/mine/7rzy) | CryoEM structure of Vibrio cholerae transposon Tn6677 AAA+ ATPase TnsC | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Tn6677 Vibrio cholerae transposon TnsC (VchTnsC) | Authors: | Hoffmann, F.T, Kim, M, Beh, L.Y, Wang, J, Vo, P.L.H, Gelsinger, D.R, Acree, C, Mohabir, J.T, Fernandez, I.S, Sternberg, S.H. | Deposit date: | 2021-08-28 | Release date: | 2022-06-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. Nature, 609, 2022
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6DXT
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![BU of 6dxt by Molmil](/molmil-images/mine/6dxt) | Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with 3-(5-phenyl-1,3,4-oxadiazol-2-yl)propanoate | Descriptor: | 1,2-ETHANEDIOL, 3-(5-phenyl-1,3,4-oxadiazol-2-yl)propanoic acid, UNKNOWN ATOM OR ION, ... | Authors: | Mann, M.K, Harding, R.J, Ravichandran, M, Ferreira de Freitas, R, Franzoni, I, Bountra, C, Edwards, A.M, Arrowsmith, C.M, Schapira, M, Structural Genomics Consortium (SGC) | Deposit date: | 2018-06-29 | Release date: | 2018-08-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain. J.Med.Chem., 62, 2019
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7SKW
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![BU of 7skw by Molmil](/molmil-images/mine/7skw) | Ab initio structure of triclinic lysozyme from electron-counted MicroED data | Descriptor: | Lysozyme C, NITRATE ION | Authors: | Martynowycz, M.W, Clabbers, M.T.B, Hattne, J, Gonen, T. | Deposit date: | 2021-10-21 | Release date: | 2022-06-08 | Last modified: | 2022-06-22 | Method: | ELECTRON CRYSTALLOGRAPHY (0.87 Å) | Cite: | Ab initio phasing macromolecular structures using electron-counted MicroED data. Nat.Methods, 19, 2022
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7SJQ
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3C6S
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![BU of 3c6s by Molmil](/molmil-images/mine/3c6s) | Crystal structure of Fab F22-4 in complex with a Shigella flexneri 2a O-Ag pentadecasaccharide | Descriptor: | Fab F22-4 heavy chain, Fab F22-4 light chain, PALLADIUM ION, ... | Authors: | Saul, F.A, Vulliez-le-Normand, B, Bentley, G.A. | Deposit date: | 2008-02-05 | Release date: | 2008-07-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody Proc.Natl.Acad.Sci.Usa, 105, 2008
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3CBQ
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![BU of 3cbq by Molmil](/molmil-images/mine/3cbq) | Crystal structure of the human REM2 GTPase with bound GDP | Descriptor: | 1,2-ETHANEDIOL, GTP-binding protein REM 2, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Nedyalkova, L, Shen, Y, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-02-22 | Release date: | 2008-03-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal structure of the human REM2 GTPase with bound GDP. To be Published
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3C4X
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8R2B
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7SKX
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![BU of 7skx by Molmil](/molmil-images/mine/7skx) | Ab initio structure of proteinase K from electron-counted MicroED data | Descriptor: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, CALCIUM ION, Proteinase K | Authors: | Martynowycz, M.W, Clabbers, M.T.B, Hattne, J, Gonen, T. | Deposit date: | 2021-10-21 | Release date: | 2022-06-08 | Last modified: | 2022-06-22 | Method: | ELECTRON CRYSTALLOGRAPHY (1.5 Å) | Cite: | Ab initio phasing macromolecular structures using electron-counted MicroED data. Nat.Methods, 19, 2022
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3C66
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![BU of 3c66 by Molmil](/molmil-images/mine/3c66) | Yeast poly(A) polymerase in complex with Fip1 residues 80-105 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Poly(A) polymerase, ... | Authors: | Bohm, A, Meinke, G. | Deposit date: | 2008-02-02 | Release date: | 2008-05-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of yeast poly(A) polymerase in complex with a peptide from Fip1, an intrinsically disordered protein. Biochemistry, 47, 2008
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8R20
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3C7G
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![BU of 3c7g by Molmil](/molmil-images/mine/3c7g) | Crystal structure of a glycoside hydrolase family 43 arabinoxylan arabinofuranohydrolase from Bacillus subtilis in complex with xylotetraose. | Descriptor: | CALCIUM ION, Endo-1,4-beta-xylanase, GLYCEROL, ... | Authors: | Vandermarliere, E, Bourgois, T.M, Winn, M.D, Van Campenhout, S, Volckaert, G, Strelkov, S.V, Delcour, J.A, Rabijns, A, Courtin, C.M. | Deposit date: | 2008-02-07 | Release date: | 2008-11-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structural analysis of a glycoside hydrolase family 43 arabinoxylan arabinofuranohydrolase in complex with xylotetraose reveals a different binding mechanism compared with other members of the same family. Biochem.J., 418, 2009
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3C7U
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2YCC
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![BU of 2ycc by Molmil](/molmil-images/mine/2ycc) | |
3C8V
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5KCZ
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![BU of 5kcz by Molmil](/molmil-images/mine/5kcz) | horse liver S48T alcohol dehydrogenase complexed with NAD and trifluoroethanol | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, Alcohol dehydrogenase E chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... | Authors: | Plapp, B.V. | Deposit date: | 2016-06-07 | Release date: | 2016-06-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Inversion of substrate stereoselectivity of horse liver alcohol dehydrogenase by substitutions of Ser-48 and Phe-93. Chem. Biol. Interact., 276, 2017
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6IEQ
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![BU of 6ieq by Molmil](/molmil-images/mine/6ieq) | Crystal Structure of HIV-1 Env ConM SOSIP.v7 in Complex with bNAb PGT124 and 35O22 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab Heavy Chain, ... | Authors: | Han, B.W, Wilson, I.A. | Deposit date: | 2018-09-16 | Release date: | 2019-05-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence. Nat Commun, 10, 2019
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