2CBO
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![BU of 2cbo by Molmil](/molmil-images/mine/2cbo) | Crystal structure of the neocarzinostatin 3Tes24 mutant bound to testosterone hemisuccinate. | Descriptor: | NEOCARZINOSTATIN, SULFATE ION, TESTOSTERONE HEMISUCCINATE | Authors: | Drevelle, A, Graille, M, Heyd, B, Sorel, I, Ulryck, N, Pecorari, F, Desmadril, M, van Tilbeurgh, H, Minard, P. | Deposit date: | 2006-01-06 | Release date: | 2006-03-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structures of in Vitro Evolved Binding Sites on Neocarzinostatin Scaffold Reveal Unanticipated Evolutionary Pathways. J.Mol.Biol., 358, 2006
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2CBT
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![BU of 2cbt by Molmil](/molmil-images/mine/2cbt) | Crystal structure of the neocarzinostatin 4Tes1 mutant bound testosterone hemisuccinate. | Descriptor: | NEOCARZINOSTATIN, TESTOSTERONE HEMISUCCINATE | Authors: | Drevelle, A, Graille, M, Heyd, B, Sorel, I, Ulryck, N, Pecorari, F, Desmadril, M, Van Tilbeurgh, H, Minard, P. | Deposit date: | 2006-01-06 | Release date: | 2006-03-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of in Vitro Evolved Binding Sites on Neocarzinostatin Scaffold Reveal Unanticipated Evolutionary Pathways. J.Mol.Biol., 358, 2006
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2BYB
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![BU of 2byb by Molmil](/molmil-images/mine/2byb) | Human Monoamine Oxidase B in complex with Deprenyl | Descriptor: | AMINE OXIDASE [FLAVIN-CONTAINING] B, DEPRENYL, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Binda, C, De Colibus, L, Edmondson, D.E, Mattevi, A. | Deposit date: | 2005-07-29 | Release date: | 2005-08-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Three-Dimensional Structure of Human Monoamine Oxidase a (Mao A): Relation to the Structures of Rat Mao a and Human Mao B Proc.Natl.Acad.Sci.USA, 102, 2005
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6FGE
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![BU of 6fge by Molmil](/molmil-images/mine/6fge) | Crystal structure of human ZUFSP/ZUP1 in complex with ubiquitin | Descriptor: | ACETATE ION, AMMONIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Kwasna, D, Abdul Rehman, S.A, Kulathu, Y. | Deposit date: | 2018-01-10 | Release date: | 2018-04-04 | Last modified: | 2018-04-18 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability. Mol. Cell, 70, 2018
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2BIW
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![BU of 2biw by Molmil](/molmil-images/mine/2biw) | Crystal structure of apocarotenoid cleavage oxygenase from Synechocystis, native enzyme | Descriptor: | (3R)-3-HYDROXY-8'-APOCAROTENOL, APOCAROTENOID-CLEAVING OXYGENASE, FE (III) ION | Authors: | Kloer, D.P, Ruch, S, Al-Babili, S, Beyer, P, Schulz, G.E. | Deposit date: | 2005-01-26 | Release date: | 2005-04-14 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | The Structure of a Retinal-Forming Carotenoid Oxygenase Science, 308, 2005
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2CBQ
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![BU of 2cbq by Molmil](/molmil-images/mine/2cbq) | Crystal structure of the neocarzinostatin 1Tes15 mutant bound to testosterone hemisuccinate. | Descriptor: | NEOCARZINOSTATIN, SULFATE ION, TESTOSTERONE HEMISUCCINATE | Authors: | Drevelle, A, Graille, M, Heyd, B, Sorel, I, Ulryck, N, Pecorari, F, Desmadril, M, Van Tilbeurgh, H, Minard, P. | Deposit date: | 2006-01-06 | Release date: | 2006-03-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of in Vitro Evolved Binding Sites on Neocarzinostatin Scaffold Reveal Unanticipated Evolutionary Pathways. J.Mol.Biol., 358, 2006
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6GGL
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![BU of 6ggl by Molmil](/molmil-images/mine/6ggl) | Crystal structure of CotB2 variant F107A | Descriptor: | CHLORIDE ION, Cyclooctat-9-en-7-ol synthase, MAGNESIUM ION | Authors: | Driller, R, Janke, S, Fuchs, M, Warner, E, Mhashal, A.R, Major, D.T, Christmann, M, Brueck, T, Loll, B. | Deposit date: | 2018-05-03 | Release date: | 2018-10-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis. Nat Commun, 9, 2018
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6FFA
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![BU of 6ffa by Molmil](/molmil-images/mine/6ffa) | FMDV Leader protease bound to substrate ISG15 | Descriptor: | GLYCEROL, Lbpro, SULFATE ION, ... | Authors: | Swatek, K.N, Pruneda, J.N, Komander, D. | Deposit date: | 2018-01-05 | Release date: | 2018-02-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6GGI
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![BU of 6ggi by Molmil](/molmil-images/mine/6ggi) | Crystal structure of CotB2 in complex with 2-fluoro-3,7,18-dolabellatriene | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-fluoro-3,7,18-dolabellatriene, ACETONITRILE, ... | Authors: | Driller, R, Janke, S, Fuchs, M, Warner, E, Mhashal, A.R, Major, D.T, Christmann, M, Brueck, T, Loll, B. | Deposit date: | 2018-05-03 | Release date: | 2018-10-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.803 Å) | Cite: | Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis. Nat Commun, 9, 2018
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6GGK
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![BU of 6ggk by Molmil](/molmil-images/mine/6ggk) | Crystal structure of CotB2 C-terminal truncation | Descriptor: | CHLORIDE ION, Cyclooctat-9-en-7-ol synthase, MAGNESIUM ION | Authors: | Driller, R, Janke, S, Fuchs, M, Warner, E, Mhashal, A.R, Major, D.T, Christmann, M, Brueck, T, Loll, B. | Deposit date: | 2018-05-03 | Release date: | 2018-10-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis. Nat Commun, 9, 2018
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6GGJ
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![BU of 6ggj by Molmil](/molmil-images/mine/6ggj) | Crystal structure of CotB2 in complex with alendronate | Descriptor: | 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, Cyclooctat-9-en-7-ol synthase, MAGNESIUM ION | Authors: | Driller, R, Janke, S, Fuchs, M, Warner, E, Mhashal, A.R, Major, D.T, Christmann, M, Brueck, T, Loll, B. | Deposit date: | 2018-05-03 | Release date: | 2018-10-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis. Nat Commun, 9, 2018
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7K0K
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![BU of 7k0k by Molmil](/molmil-images/mine/7k0k) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, 3KS-bound | Descriptor: | 3-Dehydrosphinganine, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | Deposit date: | 2020-09-04 | Release date: | 2021-02-24 | Last modified: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
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8PD0
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![BU of 8pd0 by Molmil](/molmil-images/mine/8pd0) | cryo-EM structure of Doa10 in MSP1E3D1 | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, ERAD-associated E3 ubiquitin-protein ligase DOA10 | Authors: | Botsch, J.J, Braeuning, B, Schulman, B.A. | Deposit date: | 2023-06-11 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE. Nat Commun, 15, 2024
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8PDA
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![BU of 8pda by Molmil](/molmil-images/mine/8pda) | cryo-EM structure of Doa10 with RING domain in MSP1E3D1 | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, ERAD-associated E3 ubiquitin-protein ligase DOA10 | Authors: | Botsch, J.J, Braeuning, B, Schulman, B.A. | Deposit date: | 2023-06-12 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.58 Å) | Cite: | Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE. Nat Commun, 15, 2024
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7JJU
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![BU of 7jju by Molmil](/molmil-images/mine/7jju) | Crystal structure of en exoribonuclease-resistant RNA (xrRNA) from Potato leafroll virus (PLRV) | Descriptor: | CACODYLATE ION, Guanidinium, IRIDIUM HEXAMMINE ION, ... | Authors: | Steckelberg, A.-L, Vicens, Q, Auffinger, P, Costantino, D.C, Nix, J.C, Kieft, J.S. | Deposit date: | 2020-07-27 | Release date: | 2020-09-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.604 Å) | Cite: | The crystal structure of a Polerovirus exoribonuclease-resistant RNA shows how diverse sequences are integrated into a conserved fold. Rna, 26, 2020
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8QWR
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![BU of 8qwr by Molmil](/molmil-images/mine/8qwr) | Crystal structure of CotB2 variant V80L | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Cyclooctat-9-en-7-ol synthase, ... | Authors: | Dimos, N, Himpich, S, Ringel, M, Driller, R, Major, D.T, Brueck, T, Loll, B. | Deposit date: | 2023-10-20 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of CotB2 variant V80L To Be Published
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7K4B
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![BU of 7k4b by Molmil](/molmil-images/mine/7k4b) | Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor cis-22a | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[cis-4-(3-methylphenyl)cyclohexyl]-4-(pyridin-3-yl)piperazine, CALCIUM ION, ... | Authors: | Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I. | Deposit date: | 2020-09-15 | Release date: | 2020-12-09 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Inactivation-mimicking block of the epithelial calcium channel TRPV6. Sci Adv, 6, 2020
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8QWS
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![BU of 8qws by Molmil](/molmil-images/mine/8qws) | Crystal structure of CotB2 variant V80L in complex with alendronate | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ... | Authors: | Dimos, N, Himpich, S, Ringel, M, Driller, R, Major, D.T, Brueck, T, Loll, B. | Deposit date: | 2023-10-20 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of CotB2 variant V80L in complex with alendronate To Be Published
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8Q00
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![BU of 8q00 by Molmil](/molmil-images/mine/8q00) | TssM-Ub-PA complex - A USP-like DUB from B. pseudomallei (193-430) reacted with Ub-PA | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, Polyubiquitin-B, ... | Authors: | Uthoff, M, Hermanns, T, Hofmann, K, Baumann, U. | Deposit date: | 2023-07-27 | Release date: | 2023-12-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | The structural basis for deubiquitination by the fingerless USP-type effector TssM. Life Sci Alliance, 7, 2024
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8S9S
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![BU of 8s9s by Molmil](/molmil-images/mine/8s9s) | Structure of the human ER membrane protein complex (EMC) in GDN | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Tomaleri, G.P, Nguyen, V.N, Voorhees, R.M. | Deposit date: | 2023-03-30 | Release date: | 2023-05-17 | Last modified: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | A selectivity filter in the ER membrane protein complex limits protein misinsertion at the ER. J.Cell Biol., 222, 2023
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8SLY
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![BU of 8sly by Molmil](/molmil-images/mine/8sly) | Rat TRPV2 bound with 2 CBD ligands in nanodiscs | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 2, ... | Authors: | Tan, X, Swartz, K.J. | Deposit date: | 2023-04-24 | Release date: | 2023-05-31 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Cannabidiol sensitizes TRPV2 channels to activation by 2-APB. Elife, 12, 2023
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8SLX
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![BU of 8slx by Molmil](/molmil-images/mine/8slx) | Rat TRPV2 bound with 1 CBD ligand in nanodiscs | Descriptor: | SODIUM ION, Transient receptor potential cation channel subfamily V member 2, cannabidiol | Authors: | Tan, X, Swartz, K.J. | Deposit date: | 2023-04-24 | Release date: | 2023-05-31 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Cannabidiol sensitizes TRPV2 channels to activation by 2-APB. Elife, 12, 2023
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7K4A
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![BU of 7k4a by Molmil](/molmil-images/mine/7k4a) | Cryo-EM structure of human TRPV6 in the open state | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I. | Deposit date: | 2020-09-15 | Release date: | 2020-12-09 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Inactivation-mimicking block of the epithelial calcium channel TRPV6. Sci Adv, 6, 2020
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8S9B
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![BU of 8s9b by Molmil](/molmil-images/mine/8s9b) | Cryo-EM structure of Nav1.7 with LCM | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Fan, X, Huang, J, Yan, N. | Deposit date: | 2023-03-27 | Release date: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural mapping of Na v 1.7 antagonists. Nat Commun, 14, 2023
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8S9C
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![BU of 8s9c by Molmil](/molmil-images/mine/8s9c) | Cryo-EM structure of Nav1.7 with CBZ | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Fan, X, Huang, J, Yan, N. | Deposit date: | 2023-03-27 | Release date: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural mapping of Na v 1.7 antagonists. Nat Commun, 14, 2023
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