7K4A

Cryo-EM structure of human TRPV6 in the open state

Summary for 7K4A

• Entry DOI: 10.2210/pdb7k4a/pdb
• EMDB information: 22662
• Descriptor: Transient receptor potential cation channel subfamily V member 6, CHOLESTEROL HEMISUCCINATE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (4 entities in total)
• Functional Keywords: trpv6, ion channel, open state, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 354898.30

Authors

Neuberger, A.,Nadezhdin, K.D.,Singh, A.K.,Sobolevsky, A.I. (deposition date: 2020-09-15, release date: 2020-12-09, Last modification date: 2024-03-06)

• Primary citation: Bhardwaj, R.,Lindinger, S.,Neuberger, A.,Nadezhdin, K.D.,Singh, A.K.,Cunha, M.R.,Derler, I.,Gyimesi, G.,Reymond, J.L.,Hediger, M.A.,Romanin, C.,Sobolevsky, A.I.; Inactivation-mimicking block of the epithelial calcium channel TRPV6.; Sci Adv, 6:-, 2020; PubMed: 33246965; DOI: 10.1126/sciadv.abe1508

Experimental method

ELECTRON MICROSCOPY (3.26 Å)