7K4A
Cryo-EM structure of human TRPV6 in the open state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Transient receptor potential cation channel subfamily V member 6 | polymer | 670 | 77021.8 | 4 | UniProt (Q9H1D0) Pfam (PF12796) Pfam (PF00023) Pfam (PF00520) | Homo sapiens (Human) | TrpV6,CaT-like,CaT-L,Calcium transport protein 1,CaT1,Epithelial calcium channel 2,ECaC2 |
| 2 | AA, E, F, HB, IB... (B, A, D, C) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 12 | Chemie (Y01) | |||
| 3 | AB, BA, BB, CA, CB... (C, B, D, A) | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 52 | Chemie (PCW) | |||
| 4 | U (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence modifications
A, B, C, D: 1 - 667 (UniProt: Q9H1D0)
| PDB | External Database | Details |
|---|---|---|
| Val 668 | - | expression tag |
| Pro 669 | - | expression tag |
| Arg 670 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 308087.2 | |
| Non-Polymers* | Number of molecules | 65 |
| Total formula weight | 46811.1 | |
| All* | Total formula weight | 354898.3 |
