PDB: 648 resultsInfo pagesStatus searchChemie searchBIRD

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1GYV	Gamma-adaptin appendage domain from clathrin adaptor AP1, L762E mutant Descriptor: ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT Authors: Evans, P.R, Owen, D.J, McMahon, H.M, Kent, H.M. Deposit date: 2002-04-30 Release date: 2002-08-22 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Gamma-adaptin appendage domain: structure and binding site for Eps15 and gamma-synergin. Structure, 10, 2002
1GYU	Gamma-adaptin appendage domain from clathrin adaptor AP1 Descriptor: ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT Authors: Evans, P.R, Owen, D.J, McMahon, H.M, Kent, H.M. Deposit date: 2002-04-30 Release date: 2002-08-22 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Gamma-Adaptin Appendage Domain. Structure and Binding Site for Eps15 and Gamma-Synergin Structure, 10, 2002
1GYW	Gamma-adaptin appendage domain from clathrin adaptor AP1 A753D mutant Descriptor: ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT, CHLORIDE ION Authors: Evans, P.R, Miele, A.E, Owen, D.J, McMahon, H.M, Kent, H.M. Deposit date: 2002-04-30 Release date: 2002-08-22 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Gamma-adaptin appendage domain: structure and binding site for Eps15 and gamma-synergin. Structure, 10, 2002
2HF6	Solution structure of human zeta-COP Descriptor: Coatomer subunit zeta-1 Authors: Yu, W, Jin, C, Xia, B. Deposit date: 2006-06-23 Release date: 2007-06-12 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure of human zeta-COP: direct evidences for structural similarity between COP I and clathrin-adaptor coats J.Mol.Biol., 386, 2009
7Z5C	Chimera of AP2 with FCHO2 linker domain as a fusion on Cmu2 subunit Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... Authors: Kane Dickson, V, Qu, K, Owen, D.J, Briggs, J.A, Zaccai, N.R. Deposit date: 2022-03-09 Release date: 2022-05-11 Method: ELECTRON MICROSCOPY (4.16 Å) Cite: FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
7OHO	Crystal structure of AP2 FCHO2 chimera Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta,F-BAR domain only protein 2, AP-2 complex subunit mu, ... Authors: Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. Deposit date: 2021-05-11 Release date: 2022-06-01 Method: X-RAY DIFFRACTION (2.88 Å) Cite: FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
7OHZ	Crystal structure of AP2 Mu2 - FCHO2 chimera (His6-tagged) Descriptor: AP-2 complex subunit mu,F-BAR domain only protein 2 Authors: Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. Deposit date: 2021-05-11 Release date: 2022-06-01 Method: X-RAY DIFFRACTION (2.27 Å) Cite: FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
7OI5	Crystal structure of AP2 Mu2 - FCHO2 chimera (GST cleaved) Descriptor: AP-2 complex subunit mu,F-BAR domain only protein 2, GLYCEROL Authors: Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. Deposit date: 2021-05-11 Release date: 2022-06-01 Method: X-RAY DIFFRACTION (2.61 Å) Cite: FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
7OIQ	Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (C2 crystal form) Descriptor: AP-2 complex subunit mu, F-BAR domain only protein 2 Authors: Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. Deposit date: 2021-05-12 Release date: 2022-06-01 Method: X-RAY DIFFRACTION (1.85 Å) Cite: FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
7OIT	Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (P3221 crystal form) Descriptor: AP-2 complex subunit mu, F-BAR domain only protein 2, GLYCEROL Authors: Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. Deposit date: 2021-05-12 Release date: 2022-06-01 Method: X-RAY DIFFRACTION (1.65 Å) Cite: FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
7OHI	FCHO1-peptide-AP2 alpha ear complex Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AP-2 complex subunit alpha-2, F-BAR domain only protein 1, ... Authors: Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. Deposit date: 2021-05-11 Release date: 2022-06-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.41 Å) Cite: FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch. Sci Adv, 8, 2022
1HES	MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH P-selectin INTERNALIZATION PEPTIDE SHLGTYGVFTNAA Descriptor: CLATHRIN COAT ASSEMBLY PROTEIN AP50, P-SELECTIN PEPTIDE Authors: Owen, D.J, Evans, P.R, Green, S.A. Deposit date: 2000-11-24 Release date: 2001-05-31 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3 Å) Cite: A Third Specificity-Determining Site in Mu 2 Adaptin for Sequences Upstream of Yxx Phi Sorting Motifs Traffic, 2, 2001
5ODS	Structure of a phosphoprotein-protein complex Descriptor: Clathrin heavy chain 1, LYS-GLU-SER-ALA-LEU-ARG-LYS-GLN-SEP-LEU-TYR-LEU-LYS-PHE-ASP-PRO-LEU-LEU Authors: Mukherjee, M, Bayliss, R. Deposit date: 2017-07-06 Release date: 2018-03-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.09 Å) Cite: Structure of a phosphoprotein-protein complex Embo J., 2018
6YIG	Crystal structure of the N-terminal EF-hand domain of Arabidopsis thaliana AtEH1/Pan1 Descriptor: CALCIUM ION, Calcium-binding EF hand family protein, SODIUM ION Authors: Yperman, K, Merceron, R, De Munck, S, Bloch, Y, Savvides, S.N, Pleskot, R, Van Damme, D. Deposit date: 2020-04-01 Release date: 2021-04-14 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding. Nat Commun, 12, 2021
6D83	Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer monomeric subunit Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... Authors: Buffalo, C.Z, Morris, K.L, Hurley, J.H. Deposit date: 2018-04-25 Release date: 2018-08-08 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (4.27 Å) Cite: HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
6OWO	CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 CORE BOUND TO NECAP Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... Authors: Partlow, E.A, Baker, R.W, Beacham, G.M, Chappie, J.S, Leschziner, A.E, Hollopeter, G. Deposit date: 2019-05-10 Release date: 2019-09-11 Last modified: 2020-01-08 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex. Elife, 8, 2019
6OXL	CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 (mu E302K) BOUND TO NECAP IN THE PRESENCE OF SS DNA Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... Authors: Partlow, E.A, Baker, R.W, Beacham, G.M, Chappie, J, Leschziner, A.E, Hollopeter, G. Deposit date: 2019-05-13 Release date: 2019-09-11 Last modified: 2020-01-08 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: A structural mechanism for phosphorylation-dependent inactivation of the AP2 complex. Elife, 8, 2019
1N11	D34 REGION OF HUMAN ANKYRIN-R AND LINKER Descriptor: Ankyrin, BROMIDE ION, CHLORIDE ION Authors: Michaely, P, Tomchick, D.R, Machius, M, Anderson, R.G.W. Deposit date: 2002-10-16 Release date: 2002-12-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of a 12 ANK repeat stack from human ankyrinR Embo J., 21, 2002
5FPI	Mu2 adaptin subunit of the AP2 adaptor (C-terminal domain) complexed with Integrin alpha4 internalisation peptide QYKSILQE Descriptor: AP-2 COMPLEX SUBUNIT MU, INTEGRIN ALPHA-4 SUBUNIT Authors: Owen, D.J, Evans, P.R, Ivaska, J. Deposit date: 2015-11-30 Release date: 2016-01-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.77 Å) Cite: Selective Integrin Endocytosis is Driven by Alpha Chain:Ap2 Interactions Nat.Struct.Mol.Biol., 23, 2016
6CM9	Structure of the cargo bound AP-1:Arf1:tetherin-Nef closed trimer monomeric subunit Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... Authors: Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. Deposit date: 2018-03-03 Release date: 2018-08-08 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.73 Å) Cite: HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
6CRI	Structure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimer Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... Authors: Morris, K.L, Buffalo, C.Z, Hurley, J.H. Deposit date: 2018-03-18 Release date: 2018-08-01 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (6.8 Å) Cite: HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
8T1O	AP2 bound to MSP2N2 nanodisc with Tgn38 cargo peptide; composite map Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... Authors: Baker, R.W, Cannon, K.S, Reta, S. Deposit date: 2023-06-02 Release date: 2023-07-12 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Lipid nanodiscs as a template for high-resolution cryo-EM structures of peripheral membrane proteins. J.Struct.Biol., 215, 2023
6D84	Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... Authors: Buffalo, C.Z, Morris, K.L, Hurley, J.H. Deposit date: 2018-04-25 Release date: 2018-08-08 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (6.72 Å) Cite: HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
6DFF	Structure of the cargo bound AP-1:Arf1:tetherin-Nef monomer Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ... Authors: Morris, K.L, Buffalo, C.Z, Ren, X, Hurley, J.H. Deposit date: 2018-05-14 Release date: 2018-08-08 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: HIV-1 Nefs Are Cargo-Sensitive AP-1 Trimerization Switches in Tetherin Downregulation. Cell, 174, 2018
4EN2	HIV-1 Nef in complex with MHC-I cytoplasmic domain and Mu1 adaptin subunit of AP1 adaptor (second domain) Descriptor: AP-1 complex subunit mu-1, MHC-I, Protein Nef Authors: Jia, X, Xiong, Y. Deposit date: 2012-04-12 Release date: 2012-06-20 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Structural basis of evasion of cellular adaptive immunity by HIV-1 Nef. Nat.Struct.Mol.Biol., 19, 2012

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