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8EYL
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BU of 8eyl by Molmil
Human Carbonic Anhydrase II with Tert-butyl (2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethyl)carbamate
Descriptor: 2-[[(2~{R})-1-azanyl-5-oxidanyl-1,5-bis(oxidanylidene)pentan-2-yl]carbamoyl]-6-[2-[2-[(4-sulfamoylphenyl)carbonylamino]ethoxy]ethylamino]benzoic acid, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ...
Authors:Kohlbrand, A.J, O'Herin, C.B.
Deposit date:2022-10-27
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:Development of Human Carbonic Anhydrase II Heterobifunctional Degraders.
J.Med.Chem., 2023
7D79
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BU of 7d79 by Molmil
The structure of DcsB complex with its substrate analogue
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DltD domain-containing protein, ...
Authors:Tang, Y, Zhou, J.H, Wang, G.Q.
Deposit date:2020-10-03
Release date:2021-01-27
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.10411429 Å)
Cite:A Polyketide Cyclase That Forms Medium-Ring Lactones.
J.Am.Chem.Soc., 143, 2021
7S7S
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BU of 7s7s by Molmil
Crystal structure of hydrophobin SC16, P21212
Descriptor: Hydrophobin
Authors:Vergunst, K.L, Langelaan, D.N.
Deposit date:2021-09-17
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The N-terminal tail of the hydrophobin SC16 is not required for rodlet formation.
Sci Rep, 12, 2022
1EAD
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BU of 1ead by Molmil
ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX
Descriptor: DIHYDROLIPOYL-TRANSACETYLASE, OXIDIZED COENZYME A
Authors:Mattevi, A, Hol, W.G.J.
Deposit date:1992-12-16
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
Biochemistry, 32, 1993
7A6P
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BU of 7a6p by Molmil
Structural determinants underlying the adduct lifetime in a short LOV protein PpSB2-LOV
Descriptor: DI(HYDROXYETHYL)ETHER, FLAVIN MONONUCLEOTIDE, Putative Sensory box protein
Authors:Arinkin, V, Granzin, J, Batra-Safferling, R.
Deposit date:2020-08-26
Release date:2021-03-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structural determinants underlying the adduct lifetime in the LOV proteins of Pseudomonas putida.
Febs J., 288, 2021
7SBH
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BU of 7sbh by Molmil
Crystal structure of the iron superoxide dismutase from Acinetobacter sp. Ver3
Descriptor: FE (III) ION, FLAVIN MONONUCLEOTIDE, Superoxide dismutase
Authors:Steimbruch, B.A, Albanesi, D, Repizo, G.D, Lisa, M.N.
Deposit date:2021-09-24
Release date:2022-03-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:The distinctive roles played by the superoxide dismutases of the extremophile Acinetobacter sp. Ver3.
Sci Rep, 12, 2022
7DS8
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BU of 7ds8 by Molmil
Crystal structure of actin capping protein in complex with twinflin-1/CD2AP CPI chimera peptide (CDN-TWC)
Descriptor: CD2-associated protein,Twinfilin-1, F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7DS3
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BU of 7ds3 by Molmil
Crystal structure of actin capping protein in complex with twinflin-2 C-terminus tail
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1, Twinfilin-2
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7DS6
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BU of 7ds6 by Molmil
Crystal structure of actin capping protein in complex with twinflin-1/CD2AP CPI chimera peptide (TWN-CDC)
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1, Twinfilin-1,CD2-associated protein
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7DS4
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BU of 7ds4 by Molmil
Crystal structure of actin capping protein in complex with twinflin-1 C-terminus tail F323K mutant
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1, Twinfilin-1
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7DS2
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BU of 7ds2 by Molmil
Crystal structure of actin capping protein in complex with twinflin-1 C-terminus tail
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1, Twinfilin-1
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7DSB
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BU of 7dsb by Molmil
Crystal structure of actin capping protein in complex with V-1 and twinfilin C-terminal tail
Descriptor: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1, Myotrophin, ...
Authors:Takeda, S.
Deposit date:2020-12-30
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural Insights into the Regulation of Actin Capping Protein by Twinfilin C-terminal Tail.
J.Mol.Biol., 433, 2021
7D85
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BU of 7d85 by Molmil
Crystal structure of anti-ErbB3 Fab ISU104 in complex with human ErbB3 extracellular domain 3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-ErbB3 Fab heavy chain, Anti-ErbB3 Fab light chain, ...
Authors:Yoo, Y, Cho, H.S.
Deposit date:2020-10-07
Release date:2021-04-07
Last modified:2021-06-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Novel Therapeutic Anti-ErbB3, ISU104 Exhibits Potent Antitumorigenic Activity by Inhibiting Ligand Binding and ErbB3 Heterodimerization.
Mol.Cancer Ther., 20, 2021
7V5Y
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BU of 7v5y by Molmil
Crystal structure of hexameric complex of Sa2YoeB-Sa2YefM toxin-antitoxin from Staphylococcus aureus
Descriptor: Antitoxin, Putative mRNA interferase YoeB
Authors:Xue, L, Khan, M.H, Yue, J.
Deposit date:2021-08-18
Release date:2021-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The two paralogous copies of the YoeB-YefM toxin-antitoxin module in Staphylococcus aureus differ in DNA binding and recognition patterns.
J.Biol.Chem., 298, 2022
7V5Z
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BU of 7v5z by Molmil
Crystal structure of heterotetrameric complex of Sa2YoeB-Sa2YefM toxin-antitoxin from Staphylococcus aureus
Descriptor: Antitoxin, Putative mRNA interferase YoeB
Authors:Xue, L, Khan, M.H, Yue, J.
Deposit date:2021-08-18
Release date:2021-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The two paralogous copies of the YoeB-YefM toxin-antitoxin module in Staphylococcus aureus differ in DNA binding and recognition patterns.
J.Biol.Chem., 298, 2022
7DP3
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BU of 7dp3 by Molmil
Human MCM8 N-terminal domain
Descriptor: DNA helicase MCM8, ZINC ION
Authors:Li, J, Liu, L, Liu, Y.
Deposit date:2020-12-17
Release date:2021-05-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural study of the N-terminal domain of human MCM8/9 complex.
Structure, 29, 2021
7VSG
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BU of 7vsg by Molmil
Cryo-EM structure of a human ATP11C-CDC50A flippase reconstituted in the Nanodisc in PtdSer-occluded E2-Pi state.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell cycle control protein 50A, O-[(S)-({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine, ...
Authors:Nakanishii, H, Abe, K.
Deposit date:2021-10-26
Release date:2021-12-29
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM of the ATP11C flippase reconstituted in Nanodiscs shows a distended phospholipid bilayer inner membrane around transmembrane helix 2.
J.Biol.Chem., 298, 2022
7VSH
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BU of 7vsh by Molmil
Cryo-EM structure of a human ATP11C-CDC50A flippase reconstituted in the Nanodisc in E1P state.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell cycle control protein 50A, MAGNESIUM ION, ...
Authors:Nakanishii, H, Abe, K.
Deposit date:2021-10-26
Release date:2021-12-29
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM of the ATP11C flippase reconstituted in Nanodiscs shows a distended phospholipid bilayer inner membrane around transmembrane helix 2.
J.Biol.Chem., 298, 2022
7DQK
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BU of 7dqk by Molmil
A nicotine MATE transporter, Nicotiana tabacum MATE2 (NtMATE2)
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Tanaka, Y, Tsukazaki, T, Sasaki, A, Iwaki, S.
Deposit date:2020-12-24
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structures of a nicotine MATE transporter provide insight into its mechanism of substrate transport.
Febs Lett., 595, 2021
5F1M
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BU of 5f1m by Molmil
Crystal structure of Serine/threonine phosphatase Stp1 from Staphylococcus aureus
Descriptor: MANGANESE (II) ION, Phosphorylated protein phosphatase
Authors:Zheng, W.H, Wang, T, Li, Z.G.
Deposit date:2015-11-30
Release date:2016-08-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.322 Å)
Cite:Structure-Based Identification of a Potent Inhibitor Targeting Stp1-Mediated Virulence Regulation in Staphylococcus aureus
Cell Chem Biol, 23, 2016
7S8D
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BU of 7s8d by Molmil
Structure of DNA-free SgrAI
Descriptor: CALCIUM ION, SgraIR restriction enzyme
Authors:Horton, N.C.
Deposit date:2021-09-17
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Pretransition state and apo structures of the filament-forming enzyme SgrAI elucidate mechanisms of activation and substrate specificity.
J.Biol.Chem., 298, 2022
7DDE
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BU of 7dde by Molmil
Cryo-EM structure of the Ape4 and Nbr1 complex
Descriptor: Aspartyl aminopeptidase 1,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION
Authors:Zhang, J, Ye, K.
Deposit date:2020-10-28
Release date:2021-07-14
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.
Embo J., 40, 2021
7DD9
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BU of 7dd9 by Molmil
Cryo-EM structure of the Ams1 and Nbr1 complex
Descriptor: Alpha-mannosidase,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION
Authors:Zhang, J, Ye, K.
Deposit date:2020-10-28
Release date:2021-07-14
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.
Embo J., 40, 2021
5EZD
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BU of 5ezd by Molmil
Crystal structure of a Hepatocyte growth factor activator inhibitor-1 (HAI-1) fragment covering the PKD-like 'internal' domain and Kunitz domain 1
Descriptor: ACETATE ION, Kunitz-type protease inhibitor 1, POTASSIUM ION
Authors:Hong, Z, Andreasen, P.A, Morth, J.P, Jensen, J.K.
Deposit date:2015-11-26
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of a Two-domain Fragment of Hepatocyte Growth Factor Activator Inhibitor-1: FUNCTIONAL INTERACTIONS BETWEEN THE KUNITZ-TYPE INHIBITOR DOMAIN-1 AND THE NEIGHBORING POLYCYSTIC KIDNEY DISEASE-LIKE DOMAIN.
J.Biol.Chem., 291, 2016
7S7I
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BU of 7s7i by Molmil
Crystal structure of Fab in complex with MICA alpha3 domain
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, ...
Authors:Lee, P.S, Strop, P.
Deposit date:2021-09-16
Release date:2022-10-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Residue-Level Characterization of Antibody Binding Epitopes Using Carbene Chemical Footprinting.
Anal.Chem., 95, 2023

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