7VSH
Cryo-EM structure of a human ATP11C-CDC50A flippase reconstituted in the Nanodisc in E1P state.
Summary for 7VSH
Entry DOI | 10.2210/pdb7vsh/pdb |
EMDB information | 32111 |
Descriptor | Phospholipid-transporting ATPase IG, Cell cycle control protein 50A, alpha-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | flippase, p4-atpase, membrane protein, phospholipid transporter, transport protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 167075.42 |
Authors | Nakanishii, H.,Abe, K. (deposition date: 2021-10-26, release date: 2021-12-29, Last modification date: 2022-02-16) |
Primary citation | Nakanishi, H.,Hayashida, K.,Nishizawa, T.,Oshima, A.,Abe, K. Cryo-EM of the ATP11C flippase reconstituted in Nanodiscs shows a distended phospholipid bilayer inner membrane around transmembrane helix 2. J.Biol.Chem., 298:101498-101498, 2022 Cited by PubMed: 34922944DOI: 10.1016/j.jbc.2021.101498 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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