7S7I

Crystal structure of Fab in complex with MICA alpha3 domain

Summary for 7S7I

• Entry DOI: 10.2210/pdb7s7i/pdb
• Descriptor: MHC class I chain-related protein A, Fab heavy chain, Fab light chain, ... (6 entities in total)
• Functional Keywords: immunoglobulin, checkpoint, antibody, complex, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 18
• Total formula weight: 359110.35

Authors

Lee, P.S.,Strop, P. (deposition date: 2021-09-16, release date: 2022-10-05, Last modification date: 2023-10-25)

• Primary citation: Hogan, J.M.,Lee, P.S.,Wong, S.C.,West, S.M.,Morishige, W.H.,Bee, C.,Tapia, G.C.,Rajpal, A.,Strop, P.,Dollinger, G.; Residue-Level Characterization of Antibody Binding Epitopes Using Carbene Chemical Footprinting.; Anal.Chem., 95:3922-3931, 2023; PubMed: 36791402; DOI: 10.1021/acs.analchem.2c03091

Experimental method

X-RAY DIFFRACTION (2.4 Å)