7S7I

Crystal structure of Fab in complex with MICA alpha3 domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	MHC class I chain-related protein A	polymer	103	11608.7	6	UniProt (H9CTV0) Pfam (PF07654) In PDB	Homo sapiens (Human)
2	H, I, J, U, W...	Fab heavy chain	polymer	230	24751.6	6		Homo sapiens (Human)
3	L, M, N, V, X...	Fab light chain	polymer	214	23265.8	6		Homo sapiens (Human)
4	F, A, B, E	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
5	L, B, U, E	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
6		water	water		18.0	422	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 204 - 298 (UniProt: H9CTV0)

PDB	External Database	Details
Gly 202	-	expression tag
Ser 203	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	18
	Total formula weight	357756.0
Non-Polymers*	Number of molecules	9
	Total formula weight	1354.3
All*	Total formula weight	359110.4

*Water molecules are not included.