7VSG

Cryo-EM structure of a human ATP11C-CDC50A flippase reconstituted in the Nanodisc in PtdSer-occluded E2-Pi state.

Summary for 7VSG

Entry DOI	10.2210/pdb7vsg/pdb
EMDB information	32110
Descriptor	Phospholipid-transporting ATPase IG, Cell cycle control protein 50A, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	flippase, p4-atpase, membrane protein, phospholipid transporter, transport protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	167013.14
Authors	Nakanishii, H.,Abe, K. (deposition date: 2021-10-26, release date: 2021-12-29, Last modification date: 2022-02-16)
Primary citation	Nakanishi, H.,Hayashida, K.,Nishizawa, T.,Oshima, A.,Abe, K. Cryo-EM of the ATP11C flippase reconstituted in Nanodiscs shows a distended phospholipid bilayer inner membrane around transmembrane helix 2. J.Biol.Chem., 298:101498-101498, 2022 Cited by PubMed: 34922944 DOI: 10.1016/j.jbc.2021.101498 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation