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1ZT3
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C-terminal domain of Insulin-like Growth Factor Binding Protein-1 isolated from human amniotic fluid
Descriptor: 1,4-DIETHYLENE DIOXIDE, Insulin-like growth factor binding protein 1
Authors:Sala, A, Capaldi, S, Campagnoli, M, Faggion, B, Labo, S, Perduca, M, Romano, A, Carrizo, M.E, Valli, M, Visai, L, Minchiotti, L, Galliano, M, Monaco, H.L.
Deposit date:2005-05-26
Release date:2005-06-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and Properties of the C-terminal Domain of Insulin-like Growth Factor-binding Protein-1 Isolated from Human Amniotic Fluid
J.Biol.Chem., 280, 2005
4YZY
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Crystal structures reveal transient PERK luminal domain tetramerization in ER stress signaling
Descriptor: Eukaryotic translation initiation factor 2-alpha kinase 3
Authors:Carrara, M, Prischi, F, Ali, M.M.U.
Deposit date:2015-03-25
Release date:2015-05-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling.
Embo J., 34, 2015
4TZ7
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Crystal structure of type I phosphatidylinositol 4-phosphate 5-kinase alpha from Zebrafish
Descriptor: Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
Authors:Hu, J, Qin, Y, Wang, J, Li, L, Wu, D, Ha, Y.
Deposit date:2014-07-09
Release date:2015-09-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled.
Nat Commun, 6, 2015
1YGO
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Solution Structure of the pelle Death Domain
Descriptor: Probable serine/threonine-protein kinase pelle
Authors:Moncrieffe, M.C, Stott, K.M, Gay, N.J.
Deposit date:2005-01-05
Release date:2005-07-26
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the isolated Pelle death domain.
Febs Lett., 579, 2005
1CHQ
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BU of 1chq by Molmil
SURPRISING LEADS FOR A CHOLERA TOXIN RECEPTOR BINDING ANTAGONIST; CRYSTALLOGRAPHIC STUDIES OF CTB MUTANTS
Descriptor: CHOLERA TOXIN B PENTAMER
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1995-02-15
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Surprising leads for a cholera toxin receptor-binding antagonist: crystallographic studies of CTB mutants.
Structure, 3, 1995
2PYO
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Drosophila nucleosome core
Descriptor: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
Authors:Clapier, C.R, Petosa, C, Mueller, C.W.
Deposit date:2007-05-16
Release date:2007-11-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer.
Proteins, 71, 2007
1Y9I
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Crystal structure of low temperature requirement C protein from Listeria monocytogenes
Descriptor: CALCIUM ION, GLYCEROL, MAGNESIUM ION, ...
Authors:Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2004-12-15
Release date:2004-12-28
Last modified:2021-02-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of phosphatidylglycerophosphatase (PGPase), a putative membrane-bound lipid phosphatase, reveals a novel binuclear metal binding site and two "proton wires".
Proteins, 64, 2006
1CHP
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SURPRISING LEADS FOR A CHOLERA TOXIN RECEPTOR BINDING ANTAGONIST; CRYSTALLOGRAPHIC STUDIES OF CTB MUTANTS
Descriptor: CHLORIDE ION, CHOLERA TOXIN B PENTAMER
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1995-02-15
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Surprising leads for a cholera toxin receptor-binding antagonist: crystallographic studies of CTB mutants.
Structure, 3, 1995
8EHO
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PRRSV-1 PLP2 domain bound to ubiquitin
Descriptor: 3-AMINOPROPANE, GLYCEROL, NITRATE ION, ...
Authors:Bailey-Elkin, B.A, Mark, B.L.
Deposit date:2022-09-14
Release date:2023-12-06
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis.
Plos Pathog., 19, 2023
8EHN
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PRRSV-1 PLP2 domain
Descriptor: ACETATE ION, Papain-like protease 2, ZINC ION
Authors:Bailey-Elkin, B.A, Mark, B.L.
Deposit date:2022-09-14
Release date:2023-12-06
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis.
Plos Pathog., 19, 2023
4YZD
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Crystal Structure of human phosphorylated IRE1alpha in complex with ADP-Mg
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Serine/threonine-protein kinase/endoribonuclease IRE1
Authors:Concha, N.O.
Deposit date:2015-03-24
Release date:2015-11-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.102 Å)
Cite:Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1 alpha Endoribonuclease Activity.
Mol.Pharmacol., 88, 2015
4RQK
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Crystal structure of PDK1 in complex with ATP and the PIF-pocket ligand RS1
Descriptor: 3-phosphoinositide-dependent protein kinase 1, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Rettenmaier, T.J, Wells, J.A.
Deposit date:2014-11-03
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1.
Proc.Natl.Acad.Sci.USA, 111, 2014
1TCB
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THE SEQUENCE, CRYSTAL STRUCTURE DETERMINATION AND REFINEMENT OF TWO CRYSTAL FORMS OF LIPASE B FROM CANDIDA ANTARCTICA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LIPASE, octyl beta-D-glucopyranoside
Authors:Uppenberg, J, Jones, T.A.
Deposit date:1994-02-28
Release date:1994-05-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The sequence, crystal structure determination and refinement of two crystal forms of lipase B from Candida antarctica.
Structure, 2, 1994
2VM2
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Crystal structure of barley thioredoxin h isoform 1 crystallized using PEG as precipitant
Descriptor: THIOREDOXIN H ISOFORM 1.
Authors:Maeda, K, Hagglund, P, Finnie, C, Svensson, B, Henriksen, A.
Deposit date:2008-01-21
Release date:2008-04-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Barley Thioredoxin H Isoforms Hvtrxh1 and Hvtrxh2 Reveal Features Involved in Protein Recognition and Possibly in Discriminating the Isoform Specificity.
Protein Sci., 17, 2008
1YI5
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Crystal structure of the a-cobratoxin-AChBP complex
Descriptor: Acetylcholine-binding protein, Long neurotoxin 1
Authors:Bourne, Y, Talley, T.T, Hansen, S.B, Taylor, P, Marchot, P.
Deposit date:2005-01-11
Release date:2005-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors
Embo J., 24, 2005
4XYN
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BU of 4xyn by Molmil
X-ray structure of Ca(2+)-S100B with human RAGE-derived W61 peptide
Descriptor: CALCIUM ION, Protein S100-B, Receptor for advanced glycation endproducts-derived peptide (W61)
Authors:Jensen, J.L, Indurthi, V.S.K, Neau, D, Vetter, S.W, Colbert, C.L.
Deposit date:2015-02-02
Release date:2015-05-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural insights into the binding of the human receptor for advanced glycation end products (RAGE) by S100B, as revealed by an S100B-RAGE-derived peptide complex.
Acta Crystallogr.,Sect.D, 71, 2015
1ZR0
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BU of 1zr0 by Molmil
Crystal Structure of Kunitz Domain 1 of Tissue Factor Pathway Inhibitor-2 with Bovine Trypsin
Descriptor: CALCIUM ION, Cationic trypsin, Tissue factor pathway inhibitor 2
Authors:Schmidt, A.E, Chand, H.S, Cascio, D, Kisiel, W, Bajaj, S.P.
Deposit date:2005-05-18
Release date:2005-06-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Crystal structure of Kunitz domain 1 (KD1) of tissue factor pathway inhibitor-2 in complex with trypsin. Implications for KD1 specificity of inhibition
J.Biol.Chem., 280, 2005
1ZT5
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C-terminal domain of Insulin-like Growth Factor Binding Protein-1 isolated from human amniotic fluid complexed with Iron(II)
Descriptor: 1,4-DIETHYLENE DIOXIDE, FE (II) ION, Insulin-like growth factor binding protein 1
Authors:Sala, A, Capaldi, S, Campagnoli, M, Faggion, B, Labo, S, Perduca, M, Romano, A, Carrizo, M.E, Valli, M, Visai, L, Minchiotti, L, Galliano, M, Monaco, H.L.
Deposit date:2005-05-26
Release date:2005-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.818 Å)
Cite:Structure and Properties of the C-terminal Domain of Insulin-like Growth Factor-binding Protein-1 Isolated from Human Amniotic Fluid
J.Biol.Chem., 280, 2005
1ZU1
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BU of 1zu1 by Molmil
Solution Structure of the N-terminal Zinc Fingers of the Xenopus laevis double stranded RNA binding protein ZFa
Descriptor: RNA binding protein ZFa, ZINC ION
Authors:Moller, H.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E.
Deposit date:2005-05-29
Release date:2005-09-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal zinc fingers of the Xenopus laevis double-stranded RNA-binding protein ZFa
J.Mol.Biol., 351, 2005
1BKJ
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BU of 1bkj by Molmil
NADPH:FMN OXIDOREDUCTASE FROM VIBRIO HARVEYI
Descriptor: FLAVIN MONONUCLEOTIDE, NADPH-FLAVIN OXIDOREDUCTASE, PHOSPHATE ION
Authors:Tanner, J.J, Lei, B, TU, S.-C, Krause, K.L.
Deposit date:1998-07-08
Release date:1999-01-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Flavin reductase P: structure of a dimeric enzyme that reduces flavin.
Biochemistry, 35, 1996
1V5F
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BU of 1v5f by Molmil
Crystal Structure of Pyruvate oxidase complexed with FAD and TPP, from Aerococcus viridans
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, Pyruvate oxidase, ...
Authors:Hossain, M.T, Suzuki, K, Yamamoto, T, Imamura, S, Sekiguchi, T, Takenaka, A.
Deposit date:2003-11-22
Release date:2005-06-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structures of pyruvate oxidase from Aerococcus viridans with cofactors and with a reaction intermediate reveal the flexibility of the active-site tunnel for catalysis.
Acta Crystallogr.,Sect.F, 63, 2007
2W4X
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BtGH84 in complex with STZ
Descriptor: CALCIUM ION, GLYCEROL, O-GLCNACASE BT_4395, ...
Authors:He, Y, Bubb, A, Martinez-Fleites, C, Davies, G.J.
Deposit date:2008-12-02
Release date:2009-02-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Insight Into the Mechanism of Streptozotocin Inhibition of O-Glcnacase.
Carbohydr.Res., 344, 2009
2PO3
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Crystal Structure Analysis of DesI in the presence of its TDP-sugar product
Descriptor: (2R,3R,4S,5S,6R)-3,4-DIHYDROXY-5-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)IMINO]-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL [(2R,3S,5R)-3-HYDROXY-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE, 4-dehydrase
Authors:Burgie, E.S, Holden, H.M.
Deposit date:2007-04-25
Release date:2007-08-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular Architecture of DesI: A Key Enzyme in the Biosynthesis of Desosamine
Biochemistry, 46, 2007
8QU9
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Structure of the NCOA4 (Nuclear Receptor Coactivator 4)-FTH1 (H-Ferritin) complex
Descriptor: FE (III) ION, Ferritin heavy chain, NCOA4 (Nuclear Receptor Coactivator 4)
Authors:Hoelzgen, F, Klukin, E, Zalk, R, Shahar, A, Cohen-Schwartz, S, Frank, G.A.
Deposit date:2023-10-15
Release date:2024-05-15
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structural basis for the intracellular regulation of ferritin degradation.
Nat Commun, 15, 2024
8FFD
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Crystal structure of manganeese bound Dps protein (PA0962) from Pseudomonas aeruginosa (cubic form)
Descriptor: L(+)-TARTARIC ACID, MANGANESE (II) ION, Probable dna-binding stress protein
Authors:Lovell, S, Seibold, S, Battaile, K.P, Rivera, M.
Deposit date:2022-12-08
Release date:2023-03-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Pseudomonas aeruginosa Dps (PA0962) Functions in H 2 O 2 Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity.
Int J Mol Sci, 24, 2023

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