4YZY
Crystal structures reveal transient PERK luminal domain tetramerization in ER stress signaling
Summary for 4YZY
| Entry DOI | 10.2210/pdb4yzy/pdb |
| Descriptor | Eukaryotic translation initiation factor 2-alpha kinase 3 (1 entity in total) |
| Functional Keywords | upr, er stress sensing, proteostasis, perk, dimer, signaling protein |
| Biological source | Mus musculus (Mouse) |
| Cellular location | Endoplasmic reticulum membrane; Single-pass type I membrane protein: Q9Z2B5 |
| Total number of polymer chains | 1 |
| Total formula weight | 33509.50 |
| Authors | Carrara, M.,Prischi, F.,Ali, M.M.U. (deposition date: 2015-03-25, release date: 2015-05-13, Last modification date: 2024-01-10) |
| Primary citation | Carrara, M.,Prischi, F.,Nowak, P.R.,Ali, M.M. Crystal structures reveal transient PERK luminal domain tetramerization in endoplasmic reticulum stress signaling. Embo J., 34:1589-1600, 2015 Cited by PubMed: 25925385DOI: 10.15252/embj.201489183 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
Download full validation report
