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3OIP
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BU of 3oip by Molmil
Crystal structure of Yeast telomere protein Cdc13 OB1
Descriptor: Cell division control protein 13
Authors:Sun, J, Yang, Y, Wan, K, Mao, N, Yu, T.Y, Lin, Y.C, DeZwaan, D.C, Freeman, B.C, Lin, J.J, Lue, N.F, Lei, M.
Deposit date:2010-08-19
Release date:2010-11-03
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha.
Cell Res., 21, 2011
3I1A
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BU of 3i1a by Molmil
Crystal Structure of apo Spectinomycin Phosphotransferase, APH(9)-Ia
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, Spectinomycin phosphotransferase, ...
Authors:Berghuis, A.M, Fong, D.H, Lemke, C.T, Hwang, J, Xiong, B.
Deposit date:2009-06-25
Release date:2010-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the antibiotic resistance factor spectinomycin phosphotransferase from Legionella pneumophila.
J.Biol.Chem., 285, 2010
5ARE
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BU of 5are by Molmil
Bovine mitochondrial ATP synthase state 1b
Descriptor: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ...
Authors:Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L.
Deposit date:2015-09-24
Release date:2015-10-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.
Elife, 4, 2015
7AJT
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BU of 7ajt by Molmil
Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome)
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
Authors:Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E.
Deposit date:2020-09-29
Release date:2020-12-30
Last modified:2021-02-03
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
Mol.Cell, 81, 2021
5CWR
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BU of 5cwr by Molmil
Crystal Structure of human DNA polymerase lambda L431A mutant in complex with a one nucleotide DNA gap and dCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-07-28
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
7ASV
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BU of 7asv by Molmil
Crystal structure of tWHD2 of Rpc5 subunit of human RNA Polymerase III
Descriptor: ACETATE ION, DNA-directed RNA polymerase III subunit RPC5
Authors:Vannini, A, Abascal-Palacios, G, Ramsay, E.P.
Deposit date:2020-10-28
Release date:2020-12-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of human RNA polymerase III.
Nat Commun, 11, 2020
5G5T
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BU of 5g5t by Molmil
Structure of the Argonaute protein from Methanocaldcoccus janaschii in complex with guide DNA
Descriptor: ARGONAUTE, GUIDE DNA, MAGNESIUM ION, ...
Authors:Schneider, S, Oellig, C.A, Keegan, R, Grohmann, D, Zander, A, Willkomm, S.
Deposit date:2016-06-03
Release date:2017-02-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein.
Nat Microbiol, 2, 2017
3I0Q
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BU of 3i0q by Molmil
Crystal Structure of the AMP-bound complex of Spectinomycin Phosphotransferase, APH(9)-Ia
Descriptor: ADENOSINE MONOPHOSPHATE, NICKEL (II) ION, Spectinomycin phosphotransferase
Authors:Berghuis, A.M, Fong, D.H, Lemke, C.T, Hwang, J.-Y, Xiong, B.
Deposit date:2009-06-25
Release date:2010-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the antibiotic resistance factor spectinomycin phosphotransferase from Legionella pneumophila.
J.Biol.Chem., 285, 2010
5G5S
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BU of 5g5s by Molmil
Structure of the Argonaute protein from Methanocaldcoccus janaschii
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ARGONAUTE, MAGNESIUM ION
Authors:Schneider, S, Oellig, C.A, Keegan, R, Grohmann, D, Zander, A, Willkomm, S.
Deposit date:2016-06-03
Release date:2017-02-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural and mechanistic insights into an archaeal DNA-guided Argonaute protein.
Nat Microbiol, 2, 2017
3MHR
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BU of 3mhr by Molmil
14-3-3 sigma in complex with YAP pS127-peptide
Descriptor: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ...
Authors:Schumacher, B, Skwarczynska, M, Rose, R, Ottmann, C.
Deposit date:2010-04-08
Release date:2010-09-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structure of a 14-3-3[sigma]-YAP phosphopeptide complex at 1.15 A resolution
Acta Crystallogr.,Sect.F, 66, 2010
6RA9
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BU of 6ra9 by Molmil
Novel structural features and post-translational modifications in eukaryotic elongation factor 1A2 from Oryctolagus cuniculus
Descriptor: Elongation factor 1-alpha 2, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Carriles, A.A, Hermoso, J, Gago, F.
Deposit date:2019-04-05
Release date:2020-06-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Cues for Understanding eEF1A2 Moonlighting.
Chembiochem, 22, 2021
5GPB
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BU of 5gpb by Molmil
COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
Descriptor: (1S)-1,5-anhydro-1-(phosphonomethyl)-D-glucitol, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Martin, J.L, Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
4EHP
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BU of 4ehp by Molmil
Crystal Structure of human vinculin head domain (residues 1-252) in complex with alpha-catenin (residues 277-382)
Descriptor: ACETATE ION, Catenin alpha-1, Vinculin
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2012-04-03
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:alpha-Catenin unfurls upon binding to vinculin
J.Biol.Chem., 287, 2012
5AGI
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BU of 5agi by Molmil
Crystal structure of the LeuRS editing domain of Candida albicans Mutant K510A in complex with the adduct formed by AN2690-AMP
Descriptor: GLYCEROL, POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE, [(6-AMINO-9H-PURIN-9-YL)-[5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE]-4'YL]METHYL DIHYDROGEN PHOSPHATE
Authors:Zhao, H, Palencia, A, Seiradake, E, Ghaemi, Z, Luthey-Schulten, Z, Cusack, S, Martinis, S.A.
Deposit date:2015-02-02
Release date:2015-07-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Analysis of the Resistance Mechanism of a Benzoxaborole Inhibitor Reveals Insight Into the Leucyl-tRNA Synthetase Editing Mechanism.
Acs Chem.Biol., 10, 2015
2BNK
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BU of 2bnk by Molmil
The structure of phage phi29 replication organizer protein p16.7
Descriptor: EARLY PROTEIN GP16.7
Authors:Albert, A, Asensio, J.L, Munoz-Espin, D, Gonzalez, C, Hermoso, J.A, Villar, L, Jimenez-Barbero, J, Salas, M, Meijer, W.J.J.
Deposit date:2005-03-28
Release date:2005-04-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the Functional Domain of {Varphi}29 Replication Organizer: Insights Into Oligomerization and DNA Binding.
J.Biol.Chem., 280, 2005
4IB0
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BU of 4ib0 by Molmil
X-ray Structure of cAMP dependent protein kinase A in complex with high Na+ concentration, ADP and phosphorylated peptide pSP20
Descriptor: ADENOSINE-5'-DIPHOSPHATE, SODIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ...
Authors:Gerlits, O, Kovalevsky, A.
Deposit date:2012-12-07
Release date:2013-12-11
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer.
Biochemistry, 53, 2014
6H9B
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BU of 6h9b by Molmil
1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation
Descriptor: 9-methyl-3-[1-(2-methylquinolin-4-yl)ethenyl]carbazole, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Varela, P.F, Gigant, B.
Deposit date:2018-08-03
Release date:2018-12-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation.
J. Med. Chem., 62, 2019
4PYW
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BU of 4pyw by Molmil
1.92 angstrom crystal structure of A1AT:TTAI ternary complex
Descriptor: ACE-THR-THR-ALA-ILE-NH2, Alpha-1-antitrypsin, GLYCEROL
Authors:Nyon, M.P, Day, J, Gooptu, B.
Deposit date:2014-03-28
Release date:2015-06-10
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of alpha 1 -antitrypsin upon ligand binding.
Protein Sci., 24, 2015
4O1O
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BU of 4o1o by Molmil
Crystal Structure of RNase L in complex with 2-5A
Descriptor: Ribonuclease L, [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
Authors:Huang, H, Zeqiraj, E, Ceccarelli, D.F, Sicheri, F.
Deposit date:2013-12-16
Release date:2014-02-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.
Mol.Cell, 53, 2014
3LZC
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BU of 3lzc by Molmil
Crystal structure of Dph2 from Pyrococcus horikoshii
Descriptor: Dph2
Authors:Zhang, Y, Zhu, X, Torelli, A.T, Lee, M, Dzikovski, B, Koralewski, R.M, Wang, E, Freed, J, Krebs, C, Lin, H, Ealick, S.E.
Deposit date:2010-03-01
Release date:2010-06-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.261 Å)
Cite:Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme.
Nature, 465, 2010
4NN6
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BU of 4nn6 by Molmil
Cytokine receptor complex - Crystal form 1B
Descriptor: Cytokine receptor-like factor 2, Interleukin-7 receptor subunit alpha, Thymic stromal lymphopoietin
Authors:Verstraete, K, van Schie, L, Savvides, S.N.
Deposit date:2013-11-16
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.545 Å)
Cite:Structural basis of the proinflammatory signaling complex mediated by TSLP.
Nat.Struct.Mol.Biol., 21, 2014
3NGR
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BU of 3ngr by Molmil
Crystal structure of Leishmania nucleoside diphosphate kinase b with unordered nucleotide-binding loop.
Descriptor: Nucleoside diphosphate kinase, PHOSPHATE ION
Authors:Trindade, D.M, Sousa, T.A.C.B, Tonoli, C.C.C, Santos, C.R, Arni, R.K, Ward, R.J, Oliveira, A.H.C, Murakami, M.T.
Deposit date:2010-06-13
Release date:2011-04-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Molecular adaptability of nucleoside diphosphate kinase b from trypanosomatid parasites: stability, oligomerization and structural determinants of nucleotide binding.
Mol Biosyst, 7, 2011
3KHU
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BU of 3khu by Molmil
Crystal structure of human UDP-glucose dehydrogenase Glu161Gln, in complex with thiohemiacetal intermediate
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, UDP-glucose 6-dehydrogenase, ...
Authors:Chaikuad, A, Egger, S, Yue, W.W, Guo, K, Sethi, R, Filippakopoulos, P, Muniz, J.R.C, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Kavanagh, K.L, Nidetzky, B, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2009-10-30
Release date:2009-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Kinetic Evidence That Catalytic Reaction of Human UDP-glucose 6-Dehydrogenase Involves Covalent Thiohemiacetal and Thioester Enzyme Intermediates.
J.Biol.Chem., 287, 2012
4RPX
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BU of 4rpx by Molmil
Precatalytic ternary complex of Human DNA Polymerase Beta With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine (8-oxoG) and dCTP in the presence of CaCl2
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, ACETATE ION, CALCIUM ION, ...
Authors:Vyas, R, Suo, Z.
Deposit date:2014-10-31
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Viewing Human DNA Polymerase beta Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography.
J.Am.Chem.Soc., 137, 2015
4NN7
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BU of 4nn7 by Molmil
Cytokine receptor complex - Crystal form 2
Descriptor: Cytokine receptor-like factor 2, Interleukin-7 receptor subunit alpha, Thymic stromal lymphopoietin
Authors:Verstraete, K, van Schie, L, Savvides, S.N.
Deposit date:2013-11-16
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.775 Å)
Cite:Structural basis of the proinflammatory signaling complex mediated by TSLP.
Nat.Struct.Mol.Biol., 21, 2014

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