3LZC

Crystal structure of Dph2 from Pyrococcus horikoshii

Summary for 3LZC

• Entry DOI: 10.2210/pdb3lzc/pdb
• Related: 3LZD
• Descriptor: Dph2 (2 entities in total)
• Functional Keywords: diphthamide biosynthesis, radical sam enzyme, gene triplication, biosynthetic protein
• Biological source: Pyrococcus horikoshii
• Total number of polymer chains: 2
• Total formula weight: 85076.58

Authors

Zhang, Y.,Zhu, X.,Torelli, A.T.,Lee, M.,Dzikovski, B.,Koralewski, R.M.,Wang, E.,Freed, J.,Krebs, C.,Lin, H.,Ealick, S.E. (deposition date: 2010-03-01, release date: 2010-06-23, Last modification date: 2024-02-21)

• Primary citation: Zhang, Y.,Zhu, X.,Torelli, A.T.,Lee, M.,Dzikovski, B.,Koralewski, R.M.,Wang, E.,Freed, J.,Krebs, C.,Ealick, S.E.,Lin, H.; Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme.; Nature, 465:891-896, 2010; PubMed: 20559380; DOI: 10.1038/nature09138

Experimental method

X-RAY DIFFRACTION (2.261 Å)