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6H41
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BU of 6h41 by Molmil
Structure of the complex of the IL-5 inhibitory peptide AF17121 bound to the IL-5 receptor IL-5Ralpha
Descriptor: Interleukin-5 receptor subunit alpha, VAL-ASP-GLU-CYS-TRP-ARG-ILE-ILE-ALA-SER-HIS-THR-TRP-PHE-CYS-ALA-GLU-GLU
Authors:Mueller, T.D, Scheide, J.P.
Deposit date:2018-07-20
Release date:2018-12-26
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Basis of Interleukin-5 Inhibition by the Small Cyclic Peptide AF17121.
J. Mol. Biol., 431, 2019
2QUI
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BU of 2qui by Molmil
Crystal structures of human tryptophanyl-tRNA synthetase in complex with Tryptophanamide and ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, L-TRYPTOPHANAMIDE, MAGNESIUM ION, ...
Authors:Shen, N, Ding, J.P.
Deposit date:2007-08-05
Release date:2008-04-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Catalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic states
Nucleic Acids Res., 36, 2008
3E2T
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BU of 3e2t by Molmil
The catalytic domain of chicken tryptophan hydroxylase 1 with bound tryptophan
Descriptor: FE (III) ION, IMIDAZOLE, SULFATE ION, ...
Authors:Windahl, M.S, Petersen, C.R, Christensen, H.E.C, Harris, P.
Deposit date:2008-08-06
Release date:2008-11-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of tryptophan hydroxylase with bound amino acid substrate
Biochemistry, 47, 2008
1ML2
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BU of 1ml2 by Molmil
Crystal Structure of a Mutant Variant of Cytochrome c Peroxidase with Zn(II)-(20-oxo-Protoporphyrin IX)
Descriptor: 20-OXO-PROTOPORPHYRIN IX CONTAINING ZN(II), Cytochrome c Peroxidase
Authors:Bhaskar, B, Immoos, C.E, Shimizu, H, Farmer, P.J, Poulos, T.L.
Deposit date:2002-08-29
Release date:2003-04-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A Novel Heme and Peroxide-Dependent Tryptophan-Tyrosine Cross-Link in a Mutant of Cytochrome c Peroxidase
J.Mol.Biol., 328, 2003
7JLL
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BU of 7jll by Molmil
The internal aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site and L-Tryptophan at the enzyme beta-site
Descriptor: 1,2-ETHANEDIOL, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, CESIUM ION, ...
Authors:Hilario, E, Dunn, M.F, Mueller, L.J.
Deposit date:2020-07-29
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The internal aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site and L-Tryptophan at the enzyme beta-site.
To be Published
1TBQ
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BU of 1tbq by Molmil
CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN
Descriptor: RHODNIIN, THROMBIN
Authors:Van De Locht, A, Lamba, D, Bode, W.
Deposit date:1995-03-02
Release date:1996-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin.
EMBO J., 14, 1995
1TBR
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BU of 1tbr by Molmil
CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN
Descriptor: RHODNIIN, THROMBIN
Authors:Van De Locht, A, Lamba, D, Bode, W.
Deposit date:1995-03-03
Release date:1996-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin.
EMBO J., 14, 1995
6JPL
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BU of 6jpl by Molmil
The X-ray structure of yeast tRNA methyltransferase Trm7-Trm734 in complex with S-adenosyl-L-methionine
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, S-ADENOSYLMETHIONINE, SULFATE ION, ...
Authors:Hirata, A, Okada, K, Yoshii, K, Shiraisi, H, Saijo, S, Yonezawa, K, Shimizu, N, Hori, H.
Deposit date:2019-03-27
Release date:2019-10-02
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition.
Nucleic Acids Res., 47, 2019
4FAV
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BU of 4fav by Molmil
Crystal Structure of WT MauG in Complex with Pre-Methylamine Dehydrogenase Aged 50 Days
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Yukl, E.T, Wilmot, C.M.
Deposit date:2012-05-22
Release date:2013-03-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4FA1
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BU of 4fa1 by Molmil
Crystal Structure of WT MauG in Complex with Pre-Methylamine Dehydrogenase Aged 130 Days.
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, ...
Authors:Yukl, E.T, Wilmot, C.M.
Deposit date:2012-05-21
Release date:2013-03-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4FA4
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BU of 4fa4 by Molmil
Crystal Structure of WT MauG in Complex with Pre-Methylamine Dehydrogenase Aged 10 Days
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Yukl, E.T, Wilmot, C.M.
Deposit date:2012-05-21
Release date:2013-03-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4FA9
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BU of 4fa9 by Molmil
Crystal Structure of WT MauG in Complex with Pre-Methylamine Dehydrogenase Aged 30 Days
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Yukl, E.T, Wilmot, C.M.
Deposit date:2012-05-21
Release date:2013-03-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4FA5
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BU of 4fa5 by Molmil
Crystal Structure of WT MauG in Complex with Pre-Methylamine Dehydrogenase Aged 20 Days
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Yukl, E.T, Wilmot, C.M.
Deposit date:2012-05-21
Release date:2013-03-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4FAN
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BU of 4fan by Molmil
Crystal Structure of WT MauG in Complex with Pre-Methylamine Dehydrogenase Aged 40 Days
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, ...
Authors:Yukl, E.T, Wilmot, C.M.
Deposit date:2012-05-22
Release date:2013-03-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4FB1
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BU of 4fb1 by Molmil
Crystal Structure of WT MauG in Complex with Pre-Methylamine Dehydrogenase Aged 60 Days
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, HEME C, ...
Authors:Yukl, E.T, Wilmot, C.M.
Deposit date:2012-05-22
Release date:2013-03-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4ICT
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BU of 4ict by Molmil
Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121
Descriptor: (3S,6S)-3-benzyl-6-(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Fonvielle, M, Le Du, M.-H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P.
Deposit date:2012-12-11
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES.
J.Biol.Chem., 288, 2013
4IPS
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BU of 4ips by Molmil
Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121
Descriptor: (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazin-2-one, Cytochrome P450 121, GLYCEROL, ...
Authors:Fonvielle, M, LeDu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P.
Deposit date:2013-01-10
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES.
J.Biol.Chem., 288, 2013
4IPW
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BU of 4ipw by Molmil
Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121
Descriptor: (3S,6S)-3-(3,4-dihydroxybenzyl)-6-(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, GLYCEROL, ...
Authors:Fonvielle, M, Ledu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P.
Deposit date:2013-01-10
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES.
J.Biol.Chem., 288, 2013
4IQ7
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BU of 4iq7 by Molmil
Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121
Descriptor: (3S,6S)-3-(4-hydroxybenzyl)-6-methylpiperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Fonvielle, M, Ledu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P.
Deposit date:2013-01-11
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES.
J.Biol.Chem., 288, 2013
5E7Z
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BU of 5e7z by Molmil
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis in complex with D/L-tryptophan and D-phenylalanine
Descriptor: 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase, D-PHENYLALANINE, D-TRYPTOPHAN, ...
Authors:Reichau, S, Jiao, W, Parker, E.J.
Deposit date:2015-10-13
Release date:2016-06-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using -Amino Acids.
Plos One, 11, 2016
5JHX
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BU of 5jhx by Molmil
Crystal Structure of Fungal MagKatG2 at pH 3.0
Descriptor: CITRATE ANION, Catalase-peroxidase 2, PROTOPORPHYRIN IX CONTAINING FE
Authors:Gasselhuber, B, Obinger, C, Carpena, X.
Deposit date:2016-04-21
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Interaction with the Redox Cofactor MYW and Functional Role of a Mobile Arginine in Eukaryotic Catalase-Peroxidase.
Biochemistry, 55, 2016
2FNM
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BU of 2fnm by Molmil
Activation of human carbonic anhdyrase II by exogenous proton donors
Descriptor: ZINC ION, carbonic anhydrase 2
Authors:Bhatt, D, Fisher, S.Z, Tu, C, McKenna, R, Silverman, D.N.
Deposit date:2006-01-11
Release date:2006-11-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Location of binding sites in small molecule rescue of human carbonic anhydrase II.
Biophys.J., 92, 2007
2FNK
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BU of 2fnk by Molmil
Activation of Human Carbonic Anhydrase II by exogenous proton donors
Descriptor: Carbonic anhydrase 2, ZINC ION
Authors:Bhatt, D, Fisher, S.Z, Tu, C, McKenna, R, Silverman, D.N.
Deposit date:2006-01-11
Release date:2006-11-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Location of binding sites in small molecule rescue of human carbonic anhydrase II.
Biophys.J., 92, 2007
2FNN
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BU of 2fnn by Molmil
Activation of human carbonic anhydrase II by exogenous proton donors
Descriptor: 4-METHYLIMIDAZOLE, Carbonic Anhydrase 2, ZINC ION
Authors:Bhatt, D, Fisher, S.Z, Tu, C, McKenna, R, Silverman, D.N.
Deposit date:2006-01-11
Release date:2006-11-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Location of binding sites in small molecule rescue of human carbonic anhydrase II.
Biophys.J., 92, 2007
1MKR
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BU of 1mkr by Molmil
Crystal Structure of a Mutant Variant of Cytochrome c Peroxidase (Plate like crystals)
Descriptor: Cytochrome c Peroxidase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Bhaskar, B, Immoos, C.E, Shimizu, H, Farmer, P.J, Poulos, T.L.
Deposit date:2002-08-29
Release date:2003-04-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:A Novel Heme and Peroxide-Dependent Tryptophan-Tyrosine Cross-Link in a Mutant of Cytochrome c Peroxidase
J.Mol.Biol., 328, 2003

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