2FNN

Activation of human carbonic anhydrase II by exogenous proton donors

Summary for 2FNN

• Entry DOI: 10.2210/pdb2fnn/pdb
• Related: 2FNK 2FNM
• Descriptor: Carbonic Anhydrase 2, ZINC ION, 4-METHYLIMIDAZOLE, ... (4 entities in total)
• Functional Keywords: carbonic anhydrase, proton transfer, exogenous proton donor, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P00918
• Total number of polymer chains: 1
• Total formula weight: 29369.50

Authors

Bhatt, D.,Fisher, S.Z.,Tu, C.,McKenna, R.,Silverman, D.N. (deposition date: 2006-01-11, release date: 2006-11-28, Last modification date: 2023-08-30)

• Primary citation: Bhatt, D.,Fisher, S.Z.,Tu, C.,McKenna, R.,Silverman, D.N.; Location of binding sites in small molecule rescue of human carbonic anhydrase II.; Biophys.J., 92:562-570, 2007; PubMed: 17071654; DOI: 10.1529/biophysj.106.093203

Experimental method

X-RAY DIFFRACTION (1.8 Å)