2FNN
Activation of human carbonic anhydrase II by exogenous proton donors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbonic Anhydrase 2 | polymer | 260 | 29222.0 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (human) | Carbonic anhydrase II, Carbonate dehydratase II, CA-II, Carbonic anhydrase C |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | 4-METHYLIMIDAZOLE | non-polymer | 82.1 | 1 | Chemie (4MZ) | |||
| 4 | D (A) | water | water | 18.0 | 188 | Chemie (HOH) |
Sequence modifications
A: 1 - 261 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Ala 5 | Trp 4 | engineered mutation |
| Trp 64 | His 63 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29222.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 147.5 | |
| All* | Total formula weight | 29369.5 |
