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6GGR
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BU of 6ggr by Molmil
Crystal structure of Salmonella zinc metalloprotease effector GtgA in complex with p65
Descriptor: Bacteriophage virulence determinant, CHLORIDE ION, Transcription factor p65
Authors:Jennings, E, Esposito, D, Rittinger, K, Thurston, T.
Deposit date:2018-05-03
Release date:2018-08-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Structure-function analyses of the bacterial zinc metalloprotease effector protein GtgA uncover key residues required for deactivating NF-kappa B.
J. Biol. Chem., 293, 2018
7KOH
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BU of 7koh by Molmil
Crystal structure of antigen 43 from Escherichia coli EDL933
Descriptor: Antigen 43, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Vo, J.L, Paxman, J.J, Heras, B.
Deposit date:2020-11-09
Release date:2022-03-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Variation of Antigen 43 self-association modulates bacterial compacting within aggregates and biofilms.
NPJ Biofilms Microbiomes, 8, 2022
6CRQ
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BU of 6crq by Molmil
Glutaraldehyde-treated BG505 SOSIP.664 Env in complex with PGV04 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Pallesen, J, Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-18
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.
PLoS Pathog., 14, 2018
6CYQ
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BU of 6cyq by Molmil
Crystal structure of CTX-M-14 S70G/N106S beta-lactamase in complex with hydrolyzed cefotaxime
Descriptor: (2R)-2-[(R)-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}(carboxy)methyl]-5-methylidene-5,6-dihydro -2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase, GLYCEROL
Authors:Patel, M.P, Hu, L, Sankaran, B, Brown, C, Prasad, B.V.V, Palzkill, T.
Deposit date:2018-04-06
Release date:2018-10-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Synergistic effects of functionally distinct substitutions in beta-lactamase variants shed light on the evolution of bacterial drug resistance.
J. Biol. Chem., 293, 2018
6CRX
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BU of 6crx by Molmil
SARS Spike Glycoprotein, Stabilized variant, two S1 CTDs in the upwards conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ...
Authors:Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
5V7J
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BU of 5v7j by Molmil
Crystal Structure at 3.7 A Resolution of Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer with Four Glycans (N197, N276, N362, and N462) removed in Complex with Neutralizing Antibodies 3H+109L and 35O22.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 35O22 Fab heavy chain, ...
Authors:Stewart-Jones, G.B.E, Zhou, T, Kwong, P.D.
Deposit date:2017-03-20
Release date:2017-06-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.907 Å)
Cite:Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation.
Cell Rep, 19, 2017
7M4N
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BU of 7m4n by Molmil
Crystal structure of RBR E3 ligase RNF216 in complex with K63-linked di-ubiquitin
Descriptor: E3 ubiquitin-protein ligase RNF216, GLYCEROL, SULFATE ION, ...
Authors:Cotton, T.R, Lechtenberg, B.C.
Deposit date:2021-03-21
Release date:2022-01-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216.
Mol.Cell, 82, 2022
1QTQ
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BU of 1qtq by Molmil
GLUTAMINYL-TRNA SYNTHETASE COMPLEXED WITH TRNA AND AN AMINO ACID ANALOG
Descriptor: 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE, PROTEIN (GLUTAMINYL-TRNA SYNTHETASE), RNA (TRNA GLN II ), ...
Authors:Rath, V.L, Silvian, L.F, Beijer, B, Sproat, B.S, Steitz, T.A.
Deposit date:1998-01-28
Release date:1998-05-27
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:How glutaminyl-tRNA synthetase selects glutamine.
Structure, 6, 1998
8BR1
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BU of 8br1 by Molmil
ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to Latrunculin-B-ATP-Mg-actin, and 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE and 2 Mg ions
Descriptor: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Teixeira-Nunes, M, Renault, L, Retailleau, P.
Deposit date:2022-11-22
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.044 Å)
Cite:Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.
Plos Pathog., 19, 2023
5JYQ
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BU of 5jyq by Molmil
Structure of Conus Geographus insulin G1
Descriptor: Insulin 1, Insulin 1b, SULFATE ION
Authors:Lawrence, M.C, Menting, J, Norton, R.S, Safavi-Hemami, H.
Deposit date:2016-05-15
Release date:2016-09-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.
Nat.Struct.Mol.Biol., 23, 2016
6TW1
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BU of 6tw1 by Molmil
Bat Influenza A polymerase termination complex with pyrophosphate using 44-mer vRNA template with mutated oligo(U) sequence
Descriptor: 5-oxidanyl-4-oxidanylidene-1-[(1-pyrrolo[2,3-b]pyridin-1-ylcyclopentyl)methyl]pyridine-3-carboxylic acid, MAGNESIUM ION, PYROPHOSPHATE 2-, ...
Authors:Wandzik, J.M, Kouba, T, Cusack, S.
Deposit date:2020-01-11
Release date:2020-04-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 2020
8TTT
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BU of 8ttt by Molmil
Structure of SNX27 FERM complexed with Fam21A repeat 15 (1124-1140)
Descriptor: DI(HYDROXYETHYL)ETHER, Fam21A repeat 15 peptide, GLYCEROL, ...
Authors:Guo, Q, Chen, K.-E, Collins, B.M.
Deposit date:2023-08-15
Release date:2024-08-21
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8RJX
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BU of 8rjx by Molmil
Solution structure of osmoregulator OsmY from E. coli.
Descriptor: Osmotically-inducible protein Y
Authors:Iyer, A, Luo, Y, le Paige, U.B.A, van Ingen, H.
Deposit date:2023-12-22
Release date:2024-07-03
Last modified:2024-07-17
Method:SOLUTION NMR
Cite:The Structure and Function of the Bacterial Osmotically Inducible Protein Y.
J.Mol.Biol., 436, 2024
4ZH1
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BU of 4zh1 by Molmil
Complement factor H in complex with the GM1 glycan
Descriptor: Complement C3, Complement factor H, GLYCEROL, ...
Authors:Blaum, B.S, Stehle, T.
Deposit date:2015-04-24
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Complement Factor H and Simian Virus 40 bind the GM1 ganglioside in distinct conformations.
Glycobiology, 26, 2016
8R7Q
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BU of 8r7q by Molmil
human connexin-36 gap junction channel in complex with quinine
Descriptor: Gap junction delta-2 protein, Quinine
Authors:Ding, X.Y, Blum, T.B, Korkhov, V.M.
Deposit date:2023-11-27
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:Structural basis of connexin-36 gap junction channel inhibition.
Cell Discov, 10, 2024
4CSU
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BU of 4csu by Molmil
Cryo-EM structures of the 50S ribosome subunit bound with ObgE
Descriptor: 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L11, ...
Authors:Feng, B, Mandava, C.S, Guo, Q, Wang, J, Cao, W, Li, N, Zhang, Y, Zhang, Y, Wang, Z, Wu, J, Sanyal, S, Lei, J, Gao, N.
Deposit date:2014-03-10
Release date:2014-06-04
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase.
Plos Biol., 12, 2014
8R7P
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BU of 8r7p by Molmil
human connexin-36 gap junction channel
Descriptor: Gap junction delta-2 protein
Authors:Ding, X.Y, Blum, T.B, Korkhov, V.M.
Deposit date:2023-11-27
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Structural basis of connexin-36 gap junction channel inhibition.
Cell Discov, 10, 2024
4WCZ
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BU of 4wcz by Molmil
Crystal structure of a putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans
Descriptor: Enoyl-CoA hydratase/isomerase
Authors:Tkaczuk, K.L, Cooper, D.R, Chapman, H.C, Niedzialkowska, E, Cymborowski, M.T, Hillerich, B.S, Stead, M, Ahmed, M, Hammonds, J, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2014-09-05
Release date:2014-12-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal structure of a putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans
to be published
4V55
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BU of 4v55 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with gentamicin and ribosome recycling factor (RRF).
Descriptor: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, 23S rRNA, ...
Authors:Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
Deposit date:2007-06-17
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
8QOJ
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BU of 8qoj by Molmil
human connexin-36 gap junction channel in complex with mefloquine
Descriptor: Gap junction delta-2 protein, Mefloquine
Authors:Ding, X.Y, Blum, T.B, Korkhov, V.M.
Deposit date:2023-09-29
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (2.13 Å)
Cite:Structural basis of connexin-36 gap junction channel inhibition.
Cell Discov, 10, 2024
8EN9
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BU of 8en9 by Molmil
TehA native-SAD structure determined at 5 keV with a helium environment
Descriptor: CHLORIDE ION, SODIUM ION, Tellurite resistance protein TehA homolog, ...
Authors:Karasawa, A, Andi, B, Ruchs, M.R, Shi, W, McSweeney, S, Hendrickson, W.A, Liu, Q.
Deposit date:2022-09-29
Release date:2022-11-02
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Multi-crystal native-SAD phasing at 5 keV with a helium environment.
Iucrj, 9, 2022
6L2P
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BU of 6l2p by Molmil
Threonyl-tRNA synthetase from Salmonella enterica in the apo form
Descriptor: Threonine--tRNA ligase, ZINC ION
Authors:Guo, J, Chen, B, Zhou, H.
Deposit date:2019-10-05
Release date:2020-01-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of novel tRNA-amino acid dual-site inhibitors against threonyl-tRNA synthetase by fragment-based target hopping.
Eur.J.Med.Chem., 187, 2019
7SL7
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BU of 7sl7 by Molmil
Full-length insulin receptor bound with both site 1 binding deficient mutant insulin (A-V3E) and site 2 binding deficient mutant insulin (A-L13R)
Descriptor: Insulin A chain (L13R), Insulin A chain (V3E), Insulin B chain, ...
Authors:Bai, X.C, Choi, E.
Deposit date:2021-10-22
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
6U4X
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BU of 6u4x by Molmil
Crystal structure of Equine Serum Albumin complex with ibuprofen
Descriptor: IBUPROFEN, SULFATE ION, Serum albumin, ...
Authors:Czub, M.P, Handing, K.B, Venkataramany, B.S, Steen, E.H, Shabalin, I.G, Satchell, K.J, Joachimiak, A, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2019-08-26
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Albumin-Based Transport of Nonsteroidal Anti-Inflammatory Drugs in Mammalian Blood Plasma.
J.Med.Chem., 63, 2020
7SL2
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BU of 7sl2 by Molmil
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- asymmetric conformation
Descriptor: Insulin A chain, Insulin B chain, Insulin receptor
Authors:Bai, X.C, Choi, E.
Deposit date:2021-10-22
Release date:2022-03-30
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022

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