8QOJ

human connexin-36 gap junction channel in complex with mefloquine

Summary for 8QOJ

• Entry DOI: 10.2210/pdb8qoj/pdb
• EMDB information: 18540
• Descriptor: Gap junction delta-2 protein, (11R,12S)- Mefloquine (3 entities in total)
• Functional Keywords: membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 12
• Total formula weight: 449484.94

Authors

Ding, X.Y.,Blum, T.B.,Korkhov, V.M. (deposition date: 2023-09-29, release date: 2024-07-03, Last modification date: 2024-11-13)

• Primary citation: Ding, X.,Aureli, S.,Vaithia, A.,Lavriha, P.,Schuster, D.,Khanppnavar, B.,Li, X.,Blum, T.B.,Picotti, P.,Gervasio, F.L.,Korkhov, V.M.; Structural basis of connexin-36 gap junction channel inhibition.; Cell Discov, 10:68-68, 2024; PubMed: 38890333; DOI: 10.1038/s41421-024-00691-y

Experimental method

ELECTRON MICROSCOPY (2.13 Å)