8QOJ
human connexin-36 gap junction channel in complex with mefloquine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Gap junction delta-2 protein | polymer | 330 | 37078.8 | 12 | UniProt (Q9UKL4) Pfam (PF00029) | Homo sapiens (human) | |
| 2 | M, N, O, P, Q... (A, B, C, D, E...) | (11R,12S)- Mefloquine | non-polymer | 378.3 | 12 | Chemie (YMZ) | |||
| 3 | AA, BA, CA, DA, EA... (C, D, E, F, G...) | water | water | 18.0 | 162 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 321 (UniProt: Q9UKL4)
| PDB | External Database | Details |
|---|---|---|
| Ala 322 | - | expression tag |
| Ala 323 | - | expression tag |
| Ala 324 | - | expression tag |
| Leu 325 | - | expression tag |
| Glu 326 | - | expression tag |
| Val 327 | - | expression tag |
| Leu 328 | - | expression tag |
| Phe 329 | - | expression tag |
| Gln 330 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 444945.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4539.7 | |
| All* | Total formula weight | 449484.9 |
