8SNX
 
 | | Cryo-EM structure of the respiratory syncytial virus polymerase (L:P) bound to the leader promoter | | Descriptor: | Phosphoprotein, RNA (5'-R(*UP*UP*UP*UP*UP*CP*GP*CP*GP*U)-3'), RNA-directed RNA polymerase L | | Authors: | Cao, D, Gao, Y, Chen, Z, Gooneratne, I, Roesler, C, Mera, C, Liang, B. | | Deposit date: | 2023-04-28 | | Release date: | 2023-12-20 | | Last modified: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures of the promoter-bound respiratory syncytial virus polymerase.
Nature, 625, 2024
|
|
8SNY
 | | Cryo-EM structure of the respiratory syncytial virus polymerase (L:P) bound to the trailer complementary promoter | | Descriptor: | Phosphoprotein, RNA (5'-R(*UP*UP*UP*UP*UP*CP*UP*CP*GP*U)-3'), RNA-directed RNA polymerase L | | Authors: | Cao, D, Gao, Y, Chen, Z, Gooneratne, I, Roesler, C, Mera, C, Liang, B. | | Deposit date: | 2023-04-28 | | Release date: | 2023-12-20 | | Last modified: | 2024-01-31 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Structures of the promoter-bound respiratory syncytial virus polymerase.
Nature, 625, 2024
|
|
8YOO
 | | Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | Authors: | Li, X, Wang, M, Denk, T, Cheng, J. | | Deposit date: | 2024-03-13 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2 Å) | | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
|
|
8YOP
 | | Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline | | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | Authors: | Li, X, Wang, M, Denk, T, Cheng, J. | | Deposit date: | 2024-03-13 | | Release date: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
|
|
6WRE
 | |
8XZE
 | | Crystal structure of THF-II riboswitch with THF and soaked with Ir | | Descriptor: | (6S)-5,6,7,8-TETRAHYDROFOLATE, IRIDIUM ION, MAGNESIUM ION, ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 2024
|
|
8XZP
 | | Crystal structure of folE riboswitch with 8-CH3 Guanine | | Descriptor: | 2-azanyl-8-methyl-1,9-dihydropurin-6-one, MAGNESIUM ION, RNA (53-MER), ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 2024
|
|
8XZR
 | |
8XZQ
 | | Crystal structure of folE riboswitch with 8-N Guanine | | Descriptor: | 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, MAGNESIUM ION, RNA (53-MER), ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 2024
|
|
8XZL
 | | Crystal structure of folE riboswitch with DHF | | Descriptor: | DIHYDROFOLIC ACID, MAGNESIUM ION, RNA (53-MER), ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 2024
|
|
8XZW
 | | Crystal structure of THF-II riboswitch with THF and soaked with Ir | | Descriptor: | (6S)-5,6,7,8-TETRAHYDROFOLATE, MAGNESIUM ION, RNA (53-MER), ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 2024
|
|
8XZN
 | | Crystal structure of folE riboswitch with BH4 | | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, MAGNESIUM ION, RNA (53-MER), ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 2024
|
|
8XZM
 | | Crystal structure of folE riboswitch with DHN | | Descriptor: | 2-AMINO-7,8-DIHYDRO-6-(1,2,3-TRIHYDROXYPROPYL)-4(1H)-PTERIDINONE, MAGNESIUM ION, RNA (53-MER), ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 2024
|
|
8XZO
 | | Crystal structure of folE riboswitch with Guanine | | Descriptor: | GUANINE, MAGNESIUM ION, RNA (53-MER), ... | | Authors: | Li, C.Y, Ren, A.M. | | Deposit date: | 2024-01-21 | | Release date: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Structure-based characterization and compound identification of the wild-type THF class-II riboswitch.
Nucleic Acids Res., 2024
|
|
7C5C
 | |
8SCB
 | | Terminating ribosome with SRI-41315 | | Descriptor: | (2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione, 18S_rRNA, 28S_rRNA, ... | | Authors: | Yip, M.C.J, Coelho, J.P.L, Oltion, K, Tauton, J, Shao, S. | | Deposit date: | 2023-04-05 | | Release date: | 2023-12-27 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center.
Nat.Chem.Biol., 20, 2024
|
|
4V4H
 | | Crystal structure of the bacterial ribosome from Escherichia coli in complex with the antibiotic kasugamyin at 3.5A resolution. | | Descriptor: | (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, ... | | Authors: | Schuwirth, B.S, Vila-Sanjurjo, A, Cate, J.H.D. | | Deposit date: | 2006-08-04 | | Release date: | 2014-07-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.46 Å) | | Cite: | Structural analysis of kasugamycin inhibition of translation.
Nat.Struct.Mol.Biol., 13, 2006
|
|
5KTJ
 | | Crystal structure of Pistol, a class of self-cleaving ribozyme | | Descriptor: | COBALT HEXAMMINE(III), MAGNESIUM ION, Pistol (50-MER), ... | | Authors: | Nguyen, L.A, Wang, J, Steitz, T.A. | | Deposit date: | 2016-07-11 | | Release date: | 2016-10-05 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.97 Å) | | Cite: | Crystal structure of Pistol, a class of self-cleaving ribozyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
6DJT
 | | Structure of TYW1 with a lysine-pyruvate adduct bound | | Descriptor: | DI(HYDROXYETHYL)ETHER, FE2/S3 CLUSTER, GLYCEROL, ... | | Authors: | Grell, T.A.J, Drennan, C.L. | | Deposit date: | 2018-05-26 | | Release date: | 2018-06-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4-Demethylwyosine by TYW1.
J. Am. Chem. Soc., 140, 2018
|
|
4V48
 | | Real space refined coordinates of the 30S and 50S subunits fitted into the low resolution cryo-EM map of the initiation-like state of E. coli 70S ribosome | | Descriptor: | 16S RIBOSOMAL RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | | Authors: | Gao, H, Sengupta, J, Valle, M, Korostelev, A, Eswar, N, Stagg, S.M, Van Roey, P, Agrawal, R.K, Harvey, S.T, Sali, A, Chapman, M.S, Frank, J. | | Deposit date: | 2003-05-06 | | Release date: | 2014-07-09 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (11.5 Å) | | Cite: | Study of the structural dynamics of the E. coli 70S ribosome using real space refinement
Cell(Cambridge,Mass.), 113, 2003
|
|
4V4J
 | | Interactions and Dynamics of the Shine-Dalgarno Helix in the 70S Ribosome. | | Descriptor: | 16S RNA, 23S LARGE SUBUNIT RIBOSOMAL RNA, 30S ribosomal protein S10, ... | | Authors: | Korostelev, A, Trakhanov, S, Asahara, H, Laurberg, M, Noller, H.F. | | Deposit date: | 2007-07-18 | | Release date: | 2014-07-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.83 Å) | | Cite: | Interactions and dynamics of the Shine Dalgarno helix in the 70S ribosome.
Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
4U4N
 | | Crystal structure of Edeine bound to the yeast 80S ribosome | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | Deposit date: | 2014-07-24 | | Release date: | 2014-10-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
|
|
4U4Q
 | | Crystal structure of Homoharringtonine bound to the yeast 80S ribosome | | Descriptor: | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S ribosomal RNA, 25S ribosomal RNA, ... | | Authors: | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | Deposit date: | 2014-07-24 | | Release date: | 2014-10-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
|
|
4U6F
 | | Crystal structure of T-2 toxin bound to the yeast 80S ribosome | | Descriptor: | 12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol-4,15-diacetate-8-isovalerate, 18S ribosomal RNA, 25S ribosomal RNA, ... | | Authors: | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | Deposit date: | 2014-07-28 | | Release date: | 2014-10-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
|
|
4U4U
 | | Crystal structure of Lycorine bound to the yeast 80S ribosome | | Descriptor: | (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 18S ribosomal RNA, 25S ribosomal RNA, ... | | Authors: | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | | Deposit date: | 2014-07-24 | | Release date: | 2014-10-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
|
|
