6DJT

Structure of TYW1 with a lysine-pyruvate adduct bound

Summary for 6DJT

Entry DOI	10.2210/pdb6djt/pdb
Descriptor	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, IRON/SULFUR CLUSTER, GLYCEROL, ... (6 entities in total)
Functional Keywords	s-adenosylmethionine radical enzymes, trna biosynthetic enzyme, metal binding protein
Biological source	Methanocaldococcus jannaschii (Methanococcus jannaschii)
Total number of polymer chains	1
Total formula weight	40520.74
Authors	Grell, T.A.J.,Drennan, C.L. (deposition date: 2018-05-26, release date: 2018-06-13, Last modification date: 2023-11-29)
Primary citation	Grell, T.A.J.,Young, A.P.,Drennan, C.L.,Bandarian, V. Biochemical and Structural Characterization of a Schiff Base in the Radical-Mediated Biosynthesis of 4-Demethylwyosine by TYW1. J. Am. Chem. Soc., 140:6842-6852, 2018 Cited by PubMed: 29792696 DOI: 10.1021/jacs.8b01493 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.64 Å)

Structure validation