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1U4S
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BU of 1u4s by Molmil
Plasmodium falciparum lactate dehydrogenase complexed with 2,6-naphthalenedisulphonic acid
Descriptor: L-lactate dehydrogenase, NAPHTHALENE-2,6-DISULFONIC ACID
Authors:Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L.
Deposit date:2004-07-26
Release date:2005-06-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
1U4O
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BU of 1u4o by Molmil
Plasmodium falciparum lactate dehydrogenase complexed with 2,6-naphthalenedicarboxylic acid
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2,6-DICARBOXYNAPHTHALENE, L-lactate dehydrogenase
Authors:Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L.
Deposit date:2004-07-26
Release date:2005-06-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
1U5C
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BU of 1u5c by Molmil
Plasmodium falciparum lactate dehydrogenase complexed with 3,7-dihydroxynaphthalene-2-carboxylic acid and NAD+
Descriptor: 3,7-DIHYDROXY-2-NAPHTHOIC ACID, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L.
Deposit date:2004-07-27
Release date:2005-06-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
7MDH
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BU of 7mdh by Molmil
STRUCTURAL BASIS FOR LIGHT ACITVATION OF A CHLOROPLAST ENZYME. THE STRUCTURE OF SORGHUM NADP-MALATE DEHYDROGENASE IN ITS OXIDIZED FORM
Descriptor: PROTEIN (MALATE DEHYDROGENASE), ZINC ION
Authors:Johansson, K, Ramaswamy, S, Saarinen, M, Lemaire-Chamley, M, Issakidis-Bourguet, E, Miginiac-Maslow, M, Eklund, H.
Deposit date:1999-02-16
Release date:1999-06-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for light activation of a chloroplast enzyme: the structure of sorghum NADP-malate dehydrogenase in its oxidized form.
Biochemistry, 38, 1999
7M2N
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BU of 7m2n by Molmil
Crystal structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15
Descriptor: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 5-[(5'-{1-(4-carboxy-1,3-thiazol-2-yl)-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-3-yl}-2'-fluoro[1,1'-biphenyl]-4-yl)oxy]-1H-1,2,3-triazole-4-carboxylic acid, ...
Authors:Gumpena, R, Ding, J, Powell, D.A, Lowther, W.T.
Deposit date:2021-03-17
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dual Glycolate Oxidase/Lactate Dehydrogenase A Inhibitors for Primary Hyperoxaluria
ACS Medicinal Chemistry Letters, 12, 2021
7NAY
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BU of 7nay by Molmil
Crystal structure of lactate dehydrogenase from Selenomonas ruminantium with NADH.
Descriptor: 1,2-ETHANEDIOL, BORIC ACID, L-lactate dehydrogenase, ...
Authors:Bertrand, Q, Robin, A, Girard, E, Madern, D.
Deposit date:2021-01-25
Release date:2021-02-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete allosteric regulation acquisition in the super family of lactate and malate dehydrogenases.
J.Struct.Biol., 215, 2023
3VPH
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BU of 3vph by Molmil
L-lactate dehydrogenase from Thermus caldophilus GK24 complexed with oxamate, NADH and FBP
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, L-lactate dehydrogenase, ...
Authors:Arai, K, Ohno, T, Miyanaga, A, Fushinobu, S, Taguchi, H.
Deposit date:2012-03-01
Release date:2013-03-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:The core of allosteric motion in Thermus caldophilus L-lactate dehydrogenase.
J.Biol.Chem., 2014
3VPG
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BU of 3vpg by Molmil
L-lactate dehydrogenase from Thermus caldophilus GK24
Descriptor: GLYCEROL, L-lactate dehydrogenase
Authors:Arai, K, Ohno, T, Miyanaga, A, Fushinobu, S, Taguchi, H.
Deposit date:2012-03-01
Release date:2013-03-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The core of allosteric motion in Thermus caldophilus L-lactate dehydrogenase.
J.Biol.Chem., 2014
4PLG
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BU of 4plg by Molmil
Crystal structure of ancestral apicomplexan lactate dehydrogenase with oxamate.
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, OXAMIC ACID, SODIUM ION, ...
Authors:Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L.
Deposit date:2014-05-16
Release date:2014-07-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.192 Å)
Cite:An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases.
Elife, 3, 2014
4PLY
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BU of 4ply by Molmil
Crystal structure of ancestral apicomplexan malate dehydrogenase with malate.
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, PYRUVIC ACID, malate dehydrogenase
Authors:Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L.
Deposit date:2014-05-19
Release date:2014-07-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases.
Elife, 3, 2014
4Q3N
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BU of 4q3n by Molmil
Crystal structure of MGS-M5, a lactate dehydrogenase enzyme from a Medee basin deep-sea metagenome library
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CHLORIDE ION, ...
Authors:Stogios, P.J, Xu, X, Cui, H, Alcaide, M, Ferrer, M, Savchenko, A.
Deposit date:2014-04-11
Release date:2015-02-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Pressure adaptation is linked to thermal adaptation in salt-saturated marine habitats.
Environ Microbiol, 17, 2015
4PLH
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BU of 4plh by Molmil
Crystal structure of ancestral apicomplexan malate dehydrogenase with oxamate.
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, OXAMIC ACID, SODIUM ION, ...
Authors:Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L.
Deposit date:2014-05-16
Release date:2014-07-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases.
Elife, 3, 2014
4PLW
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BU of 4plw by Molmil
Crystal structure of ancestral apicomplexan malate dehydrogenase with lactate.
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, PHOSPHATE ION, malate dehydrogenase
Authors:Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L.
Deposit date:2014-05-19
Release date:2014-07-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases.
Elife, 3, 2014
4PLC
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BU of 4plc by Molmil
Crystal structure of ancestral apicomplexan lactate dehydrogenase with malate.
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID, ...
Authors:Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L.
Deposit date:2014-05-16
Release date:2014-07-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases.
Elife, 3, 2014
3ZH2
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BU of 3zh2 by Molmil
Structure of Plasmodium falciparum lactate dehydrogenase in complex with a DNA aptamer
Descriptor: DNA APTAMER, L-LACTATE DEHYDROGENASE
Authors:Cheung, Y.W, Kwok, J, Law, A.W.L, Watt, R.M, Kotaka, M, Tanner, J.A.
Deposit date:2012-12-20
Release date:2013-09-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Discriminatory Recognition of Plasmodium Lactate Dehydrogenase by a DNA Aptamer
Proc.Natl.Acad.Sci.USA, 110, 2013
4PLV
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BU of 4plv by Molmil
Crystal structure of ancestral apicomplexan malate dehydrogenase with lactate.
Descriptor: (2S)-2-HYDROXYPROPANOIC ACID, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, malate dehydrogenase
Authors:Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L.
Deposit date:2014-05-19
Release date:2014-07-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases.
Elife, 3, 2014
4PLF
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BU of 4plf by Molmil
Crystal structure of ancestral apicomplexan lactate dehydrogenase with lactate.
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID, ...
Authors:Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L.
Deposit date:2014-05-16
Release date:2014-07-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases.
Elife, 3, 2014
4PLZ
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BU of 4plz by Molmil
Crystal structure of Plasmodium falciparum lactate dehydrogenase mutant W107fA.
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase, OXAMIC ACID
Authors:Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L.
Deposit date:2014-05-20
Release date:2014-07-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases.
Elife, 3, 2014
4PLT
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BU of 4plt by Molmil
Crystal structure of ancestral apicomplexan malate dehydrogenase with oxamate.
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, OXAMIC ACID, malate dehydrogenase
Authors:Boucher, J.I, Jacobowitz, J.R, Beckett, B.C, Classen, S, Theobald, D.L.
Deposit date:2014-05-19
Release date:2014-07-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases.
Elife, 3, 2014
4B7U
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BU of 4b7u by Molmil
PLASMODIUM FALCIPARUM L-LACTATE DEHYDROGENASE COMPLEXED WITH BICINE
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, BICINE, ...
Authors:Birkinshaw, R.W, Brady, R.L.
Deposit date:2012-08-22
Release date:2012-10-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:The Crystal Structure of Plasmodium Falciparum L- Lactate Dehydrogenase in Complex with a Novel Bicine Ligand
To be Published
3CZM
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BU of 3czm by Molmil
T. Gondii bradyzoite-specific LDH (LDH2) in complex with NAD and OXQ
Descriptor: 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Wilson, D.K, Susko, M.S.
Deposit date:2008-04-29
Release date:2009-06-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:T. Gondii bradyzoite-specific LDH (LDH2) in complex with NAD and OXQ
To be Published
3D5T
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BU of 3d5t by Molmil
Crystal structure of malate dehydrogenase from Burkholderia pseudomallei
Descriptor: MAGNESIUM ION, Malate dehydrogenase, SODIUM ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-05-16
Release date:2008-06-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal Structure of Malate Dehydrogenase from Burkholderia pseudomallei.
To be Published
3D0O
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BU of 3d0o by Molmil
Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus
Descriptor: L-lactate dehydrogenase 1
Authors:Ho, M, Gutierrez, J.A, Almo, S.C, Schramm, V.L.
Deposit date:2008-05-02
Release date:2009-05-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus
To be Published
3D4P
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BU of 3d4p by Molmil
Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus complexed with NAD and pyruvate
Descriptor: L-lactate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID
Authors:Schramm, V.L, Almo, S.C, Gutierrez, J.A, Ho, M.
Deposit date:2008-05-14
Release date:2009-06-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of Lactate Dehydrogenase from Staphylococcus Aureus complexed with NAD and pyruvate
To be Published
6SBU
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BU of 6sbu by Molmil
X-ray Structure of Human LDHA with an Allosteric Inhibitor (Compound 3)
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-[[4-[(5-chloranylthiophen-2-yl)carbonylamino]-1,3-bis(oxidanylidene)isoindol-2-yl]methyl]benzoic acid, L-lactate dehydrogenase A chain
Authors:Friberg, A, Puetter, V, Nguyen, D, Rehwinkel, H.
Deposit date:2019-07-22
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structural Evidence for Isoform-Selective Allosteric Inhibition of Lactate Dehydrogenase A.
Acs Omega, 5, 2020

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