1U5C

Plasmodium falciparum lactate dehydrogenase complexed with 3,7-dihydroxynaphthalene-2-carboxylic acid and NAD+

Summary for 1U5C
Related1u40 1u4s 1u5a
DescriptorL-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 3,7-DIHYDROXY-2-NAPHTHOIC ACID, ... (4 entities in total)
Functional Keywordsprotein-ligand complex, oxidoreductase
Biological sourcePlasmodium falciparum (malaria parasite P. falciparum)
Total number of polymer chains1
Total formula weight35713.99
Authors
Conners, R.,Cameron, A.,Read, J.,Schambach, F.,Sessions, R.B.,Brady, R.L. (deposition date: 2004-07-27, release date: 2005-06-21, Last modification date: 2011-07-13)
Primary citationBrady, R.L.,Cameron, A.,Conners, R.,Croft, S.L.,Easton, A.,Read, J.,Schambach, F.,Sessions, R.B.,Vivas, L.
Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142:137-148, 2005
PubMed: 15978953
DOI: 110.1016/j.molbiopara.2005.03.015
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.65 Å)
Structure validation
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PDB entries from 2021-06-16