1U5C
Plasmodium falciparum lactate dehydrogenase complexed with 3,7-dihydroxynaphthalene-2-carboxylic acid and NAD+
Summary for 1U5C
| Entry DOI | 10.2210/pdb1u5c/pdb |
| Related | 1u40 1u4s 1u5a |
| Descriptor | L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 3,7-DIHYDROXY-2-NAPHTHOIC ACID, ... (4 entities in total) |
| Functional Keywords | protein-ligand complex, oxidoreductase |
| Biological source | Plasmodium falciparum (malaria parasite P. falciparum) |
| Total number of polymer chains | 1 |
| Total formula weight | 35713.99 |
| Authors | Conners, R.,Cameron, A.,Read, J.,Schambach, F.,Sessions, R.B.,Brady, R.L. (deposition date: 2004-07-27, release date: 2005-06-21, Last modification date: 2023-08-23) |
| Primary citation | Conners, R.,Schambach, F.,Read, J.,Cameron, A.,Sessions, R.B.,Vivas, L.,Easton, A.,Croft, S.L.,Brady, R.L. Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase. Mol.Biochem.Parasitol., 142:137-148, 2005 Cited by PubMed: 15978953DOI: 10.1016/j.molbiopara.2005.03.015 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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