4PLY

Crystal structure of ancestral apicomplexan malate dehydrogenase with malate.

Summary for 4PLY

Entry DOI	10.2210/pdb4ply/pdb
Related	4PLC 4PLF 4PLG 4PLH 4PLT 4PLV 4PLW 4PLZ
Descriptor	malate dehydrogenase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, PYRUVIC ACID, ... (4 entities in total)
Functional Keywords	ancestral sequence reconstruction, dehydrogenase, apicomplexa, specificity, oxidoreductase
Biological source	Apicomplexa
Total number of polymer chains	8
Total formula weight	297523.59
Authors	Boucher, J.I.,Jacobowitz, J.R.,Beckett, B.C.,Classen, S.,Theobald, D.L. (deposition date: 2014-05-19, release date: 2014-07-02, Last modification date: 2023-11-15)
Primary citation	Boucher, J.I.,Jacobowitz, J.R.,Beckett, B.C.,Classen, S.,Theobald, D.L. An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases. Elife, 3:e02304-e02304, 2014 Cited by PubMed: 24966208 DOI: 10.7554/eLife.02304 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation