7M2N
Crystal structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15
Summary for 7M2N
| Entry DOI | 10.2210/pdb7m2n/pdb |
| Descriptor | L-lactate dehydrogenase A chain, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, SULFATE ION, ... (8 entities in total) |
| Functional Keywords | oxidoreductase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 162655.83 |
| Authors | Gumpena, R.,Ding, J.,Powell, D.A.,Lowther, W.T. (deposition date: 2021-03-17, release date: 2021-07-14, Last modification date: 2023-10-18) |
| Primary citation | Ding, J.,Gumpena, R.,Boily, M.O.,Caron, A.,Chong, O.,Cox, J.H.,Dumais, V.,Gaudreault, S.,Graff, A.H.,King, A.,Knight, J.,Oballa, R.,Surendradoss, J.,Tang, T.,Wu, J.,Lowther, W.T.,Powell, D.A. Dual Glycolate Oxidase/Lactate Dehydrogenase A Inhibitors for Primary Hyperoxaluria ACS Medicinal Chemistry Letters, 12:1116-1123, 2021 Cited by DOI: 10.1021/acsmedchemlett.1c00196PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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