PDB: 8631 resultsInfo pagesStatus searchChemie searchBIRD

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6X43	Mfd-bound E.coli RNA polymerase elongation complex - II state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. Deposit date: 2020-05-22 Release date: 2021-02-03 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural basis for transcription complex disruption by the Mfd translocase. Elife, 10, 2021
7XW2	Cryo-EM structure of human DICER-pre-miRNA in a dicing state Descriptor: CALCIUM ION, Endoribonuclease Dicer, RNA (73-MER) Authors: Lee, H, Roh, S.-H. Deposit date: 2022-05-26 Release date: 2023-03-08 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.04 Å) Cite: Structure of the human DICER-pre-miRNA complex in a dicing state. Nature, 615, 2023
6PB4	The E. coli class-II CAP-dependent transcription activation complex with de novo RNA transcript at the state 2 Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Liu, B, Shi, W. Deposit date: 2019-06-13 Release date: 2020-03-18 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.35 Å) Cite: Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
6PB6	The E. coli class-II CAP-dependent transcription activation complex at the state 2 Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Liu, B, Shi, W. Deposit date: 2019-06-13 Release date: 2020-03-18 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (4.29 Å) Cite: Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
6PB5	The E. coli class-II CAP-dependent transcription activation complex at the state 1 architecture Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Liu, B, Shi, W. Deposit date: 2019-06-13 Release date: 2020-03-18 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (4.52 Å) Cite: Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
5M9Z	Second zinc-binding domain from yeast Pcf11 Descriptor: Protein PCF11, ZINC ION Authors: Mackereth, C. Deposit date: 2016-11-02 Release date: 2017-08-02 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Distinct roles of Pcf11 zinc-binding domains in pre-mRNA 3'-end processing. Nucleic Acids Res., 45, 2017
6XH8	CueR-transcription activation complex with RNA transcript Descriptor: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Liu, B, Shi, W, Yang, Y. Deposit date: 2020-06-18 Release date: 2021-04-14 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural basis of copper-efflux-regulator-dependent transcription activation. Iscience, 24, 2021
6X50	Mfd-bound E.coli RNA polymerase elongation complex - V state Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Llewelyn, E, Chen, J, Kang, J.Y, Darst, S.A. Deposit date: 2020-05-24 Release date: 2021-02-03 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis for transcription complex disruption by the Mfd translocase. Elife, 10, 2021
6XH7	CueR-TAC without RNA Descriptor: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Liu, B, Shi, W, Yang, Y. Deposit date: 2020-06-18 Release date: 2021-04-14 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural basis of copper-efflux-regulator-dependent transcription activation. Iscience, 24, 2021
5N9J	Core Mediator of transcriptional regulation Descriptor: Mediator Complex Subunit 9, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... Authors: Nozawa, K, Schneider, T.R, Cramer, P. Deposit date: 2017-02-25 Release date: 2017-05-17 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Core Mediator structure at 3.4 Angstrom extends model of transcription initiation complex. Nature, 545, 2017
8PNT	Structure of the human nuclear cap-binding complex bound to PHAX and m7G-capped RNA Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... Authors: Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. Deposit date: 2023-07-01 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (3.46 Å) Cite: Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
6XZG	Influenza C virus polymerase in complex with chicken ANP32A - Subclass 3 Descriptor: Influenza viral RNA (vRNA) promoter 47mer, LRRcap domain-containing protein, Polymerase acidic protein, ... Authors: Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. Deposit date: 2020-02-04 Release date: 2020-11-25 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
6XZR	Influenza C virus polymerase in complex with chicken ANP32A - Subclass 1 Descriptor: LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. Deposit date: 2020-02-05 Release date: 2020-11-25 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
6XZP	Influenza C virus polymerase in complex with chicken ANP32A - Subclass 4 Descriptor: LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. Deposit date: 2020-02-05 Release date: 2020-11-25 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
6CCE	Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Kanglemycin A Descriptor: 1,2-ETHANEDIOL, DNA (57-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Lilic, M, Darst, S.A, Campbell, E.A. Deposit date: 2018-02-07 Release date: 2018-08-15 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.05 Å) Cite: Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nat Commun, 9, 2018
5D4D	Crystal structure of Thermus thermophilus product complex for transcription initiation with NAD and CTP Descriptor: ADENOSINE MONOPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, ... Authors: Zhang, Y, Ebright, R.H. Deposit date: 2015-08-07 Release date: 2016-07-06 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (3 Å) Cite: The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA. Nature, 535, 2016
5D4C	Crystal structure of Thermus thermophilus product complex for transcription initiation with ATP and CTP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, ... Authors: Zhang, Y, Ebright, R.H. Deposit date: 2015-08-07 Release date: 2016-07-06 Last modified: 2024-07-03 Method: X-RAY DIFFRACTION (3.28 Å) Cite: The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA. Nature, 535, 2016
6JCY	Mycobacterium tuberculosis RNA polymerase transcription initiation open complex with a chimeric ECF sigma factor sigH/E Descriptor: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Li, L, Zhang, Y. Deposit date: 2019-01-30 Release date: 2019-05-29 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.106 Å) Cite: Structures and mechanism of transcription initiation by bacterial ECF factors. Nucleic Acids Res., 47, 2019
1Q79	CRYSTAL STRUCTURE OF MAMMALIAN POLY(A) POLYMERASE Descriptor: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MANGANESE (II) ION, ... Authors: Martin, G, Moglich, A, Keller, W, Doublie, S. Deposit date: 2003-08-16 Release date: 2004-09-07 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Biochemical and structural insights into substrate binding and catalytic mechanism of mammalian poly(A) polymerase. J.Mol.Biol., 341, 2004
1N35	lambda3 elongation complex with four phosphodiester bond formed Descriptor: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*CP*CP*CP*CP*C)-3', 5'-R(P*GP*GP*GP*GP*G)-3', ... Authors: Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. Deposit date: 2002-10-25 Release date: 2002-12-25 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3 Cell(Cambridge,Mass.), 111, 2002
3K5M	Crystal structure of E.coli Pol II-abasic DNA-ddGTP Lt(-2, 2) ternary complex Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*TP*CP*CP*TP*GP*(3DR)P*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... Authors: Yang, W, Wang, F. Deposit date: 2009-10-07 Release date: 2010-02-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
5ZX2	Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor sigma H and 7nt RNA Descriptor: DNA (47-MER), DNA (48-MER), DNA-directed RNA polymerase subunit alpha, ... Authors: Li, L, Zhang, Y. Deposit date: 2018-05-17 Release date: 2019-03-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis for transcription initiation by bacterial ECF sigma factors. Nat Commun, 10, 2019
6FHI	Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 19-mer serine 5 phosphorylated Pol II CTD peptide with a truncated linker. Descriptor: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Lukarska, M, Cusack, S. Deposit date: 2018-01-14 Release date: 2019-01-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain To Be Published
6FHH	Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 22-mer modified Pol II CTD peptide with serine 5 thiophosphorylated. Descriptor: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Lukarska, M, Cusack, S. Deposit date: 2018-01-14 Release date: 2019-01-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain To Be Published
4M5D	Crystal structure of the Utp22 and Rrp7 complex from Saccharomyces cerevisiae Descriptor: Ribosomal RNA-processing protein 7, SULFATE ION, TRIETHYLENE GLYCOL, ... Authors: Lin, J, Ye, K. Deposit date: 2013-08-08 Release date: 2013-11-06 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.97 Å) Cite: An RNA-Binding Complex Involved in Ribosome Biogenesis Contains a Protein with Homology to tRNA CCA-Adding Enzyme. Plos Biol., 11, 2013

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