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6T7C
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BU of 6t7c by Molmil
Structure of two copies of human Sox11 transcription factor in complex with a nucleosome
Descriptor: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P.
Deposit date:2019-10-21
Release date:2020-04-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.
Nature, 580, 2020
6T7B
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BU of 6t7b by Molmil
Structure of human Sox2 transcription factor in complex with a nucleosome
Descriptor: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P.
Deposit date:2019-10-21
Release date:2020-04-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.
Nature, 580, 2020
6T7A
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BU of 6t7a by Molmil
Structure of human Sox11 transcription factor in complex with a nucleosome
Descriptor: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P.
Deposit date:2019-10-21
Release date:2020-04-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.
Nature, 580, 2020
6T78
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BU of 6t78 by Molmil
Structure of human Sox11 transcription factor in complex with a short DNA fragment
Descriptor: DNA (5'-D(*AP*AP*CP*AP*AP*AP*AP*TP*AP*AP*AP*CP*AP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*TP*GP*TP*TP*TP*AP*TP*TP*TP*TP*GP*TP*T)-3'), Transcription factor SOX-11
Authors:Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P.
Deposit date:2019-10-21
Release date:2020-04-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.
Nature, 580, 2020
6T90
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BU of 6t90 by Molmil
OCT4-SOX2-bound nucleosome - SHL-6
Descriptor: DNA (146-MER), Green fluorescent protein,POU domain, class 5, ...
Authors:Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H.
Deposit date:2019-10-25
Release date:2020-05-06
Last modified:2020-07-08
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Science, 368, 2020
6L6Y
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BU of 6l6y by Molmil
Crystal Structure of Pluripotency Reprogramming Factor Sox17 mutant (Sox17EK) HMG Domain bound to DNA
Descriptor: DNA (5'-D(*CP*CP*AP*GP*GP*AP*CP*AP*AP*TP*AP*GP*AP*GP*AP*C)-3'), DNA (5'-D(P*GP*GP*TP*CP*TP*CP*TP*AP*TP*TP*GP*TP*CP*CP*TP*G)-3'), SULFATE ION, ...
Authors:Balasubramanian, M, Kolatkar, P.R.
Deposit date:2019-10-29
Release date:2020-11-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure of Pluripotency Reprogramming Factor Sox17 mutant (Sox17EK) HMG Domain bound to DNA
To Be Published
6LTJ
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BU of 6ltj by Molmil
Structure of nucleosome-bound human BAF complex
Descriptor: AT-rich interactive domain-containing protein 1A, Actin, cytoplasmic 1, ...
Authors:He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y.
Deposit date:2020-01-22
Release date:2020-02-12
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of nucleosome-bound human BAF complex.
Science, 367, 2020
6LTH
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BU of 6lth by Molmil
Structure of human BAF Base module
Descriptor: AT-rich interactive domain-containing protein 1A, SWI/SNF complex subunit SMARCC2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, ...
Authors:He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y.
Deposit date:2020-01-22
Release date:2020-02-12
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of nucleosome-bound human BAF complex.
Science, 367, 2020
6YOV
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BU of 6yov by Molmil
OCT4-SOX2-bound nucleosome - SHL+6
Descriptor: DNA (142-MER), Green fluorescent protein,POU domain, class 5, ...
Authors:Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H.
Deposit date:2020-04-15
Release date:2020-05-06
Last modified:2020-07-08
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Science, 368, 2020
6WX7
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BU of 6wx7 by Molmil
SOX2 bound to Importin-alpha 2
Descriptor: Importin subunit alpha-1, Transcription factor SOX-2
Authors:Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N.
Deposit date:2020-05-09
Release date:2020-10-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Nat Commun, 12, 2021
6WX8
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BU of 6wx8 by Molmil
SOX2 bound to Importin-alpha 3
Descriptor: Importin subunit alpha-3, SULFATE ION, Transcription factor SOX-2
Authors:Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N.
Deposit date:2020-05-10
Release date:2020-10-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Nat Commun, 12, 2021
6WX9
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BU of 6wx9 by Molmil
SOX2 bound to Importin-alpha 5
Descriptor: Importin subunit alpha-5, Transcription factor SOX-2
Authors:Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N.
Deposit date:2020-05-10
Release date:2020-10-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Nat Commun, 12, 2021
7JJK
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BU of 7jjk by Molmil
Crystal structure of SOX30
Descriptor: Transcription factor SOX-30
Authors:Ghafoori, S.M, Forwood, J.K.
Deposit date:2020-07-27
Release date:2020-08-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of SOX30 at 1.40 Angstroms resolution
To Be Published
7CYU
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BU of 7cyu by Molmil
Crystal structure of human BAF57 HMG domain
Descriptor: SULFATE ION, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
Authors:Heo, Y, Yun, J.H, Park, J.H, Lee, W.
Deposit date:2020-09-04
Release date:2020-10-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of the HMG domain of human BAF57 and its interaction with four-way junction DNA.
Biochem.Biophys.Res.Commun., 533, 2020
7LBW
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BU of 7lbw by Molmil
Crystal structure of TFAM (mitochondrial transcription factor A) bridging two non-sequence specific DNA substrates
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(P*TP*AP*GP*CP*CP*TP*TP*TP*CP*TP*AP*TP*TP*AP*GP*CP*TP*CP*TP*TP*AP*G)-3'), ...
Authors:Choi, W.S, Garcia-Diaz, M.
Deposit date:2021-01-09
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:A minimal motif for sequence recognition by mitochondrial transcription factor A (TFAM).
Nucleic Acids Res., 50, 2022
7LBX
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BU of 7lbx by Molmil
Crystal structure of TFAM (mitochondrial transcription factor A) in complex with LSP
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(P*TP*TP*AP*AP*CP*AP*GP*TP*CP*AP*CP*CP*CP*CP*CP*CP*AP*AP*CP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*AP*GP*TP*TP*GP*GP*GP*GP*GP*GP*TP*GP*AP*CP*TP*GP*TP*TP*AP*A)-3'), ...
Authors:Choi, W.S, Garcia-Diaz, M.
Deposit date:2021-01-09
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A minimal motif for sequence recognition by mitochondrial transcription factor A (TFAM).
Nucleic Acids Res., 50, 2022
7M5W
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BU of 7m5w by Molmil
Crystal structure of the HMG-C1 domain of human capicua bound to DNA
Descriptor: CALCIUM ION, DNA (5'-D(*GP*CP*TP*TP*TP*TP*TP*CP*AP*TP*TP*CP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*TP*AP*TP*GP*AP*AP*TP*GP*AP*AP*AP*AP*AP*GP*C)-3'), ...
Authors:Webb, J.P, Liew, J.J.M, Gnann, A.D, Dowling, D.P.
Deposit date:2021-03-25
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Molecular basis of DNA recognition by the HMG-box-C1 module of Capicua
Biorxiv, 2022
7VDV
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BU of 7vdv by Molmil
The overall structure of human chromatin remodeling PBAF-nucleosome complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2,AT-rich interactive domain-containing protein 2, Actin, ...
Authors:Chen, Z.C, Chen, K.J, Yuan, J.J.
Deposit date:2021-09-07
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of human chromatin-remodelling PBAF complex bound to a nucleosome.
Nature, 605, 2022
7Y8R
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BU of 7y8r by Molmil
The nucleosome-bound human PBAF complex
Descriptor: ACTB protein (Fragment), ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2, ...
Authors:Wang, L, Yu, J, Yu, Z, Wang, Q, He, S, Xu, Y.
Deposit date:2022-06-24
Release date:2022-12-07
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure of nucleosome-bound human PBAF complex.
Nat Commun, 13, 2022
7YHP
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BU of 7yhp by Molmil
CryoEM structure of Arabidopsis ROS1 in complex with 5mC-dsDNA at 3.1 Angstroms resolution
Descriptor: DNA (40-MER), IRON/SULFUR CLUSTER, Sex-determining region Y protein,REPRESSOR OF SILENCING 1,DNA glycosylase/AP lyase ROS1
Authors:Du, X, Du, J.
Deposit date:2022-07-14
Release date:2022-11-30
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Molecular basis of the plant ROS1-mediated active DNA demethylation.
Nat.Plants, 9, 2023
7YHO
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BU of 7yho by Molmil
CryoEM structure of Arabidopsis ROS1 in complex with TG mismatch dsDNA at 3.3 Angstroms resolution
Descriptor: DNA (40-MER), IRON/SULFUR CLUSTER, Sex-determining region Y protein,DNA glycosylase/AP lyase ROS1
Authors:Du, X, Du, J.
Deposit date:2022-07-14
Release date:2022-11-30
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis of the plant ROS1-mediated active DNA demethylation.
Nat.Plants, 9, 2023
7YHQ
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BU of 7yhq by Molmil
CryoEM structure of Arabidopsis ROS1 in complex with a covalent-linked reaction intermediate at 3.9 Angstroms resolution
Descriptor: DNA (40-MER), IRON/SULFUR CLUSTER, Sex-determining region Y protein,DNA glycosylase/AP lyase ROS1
Authors:Du, X, Du, J.
Deposit date:2022-07-14
Release date:2022-11-30
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular basis of the plant ROS1-mediated active DNA demethylation.
Nat.Plants, 9, 2023
8BX1
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BU of 8bx1 by Molmil
Oct4/Sox2 protein:DNA complex
Descriptor: HOXB1_f, HOXB1_r, POU domain, ...
Authors:Chojnowski, G, Wilmanns, M, Round, E.
Deposit date:2022-12-07
Release date:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of Oct4-Soc2-HoxB1 complex
To Be Published
8BX2
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BU of 8bx2 by Molmil
Oct4/Sox2 protein:DNA complex
Descriptor: POU domain, class 5, transcription factor 1, ...
Authors:Chojnowski, G, Wilmanns, M, Round, E.
Deposit date:2022-12-07
Release date:2023-12-20
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Crystal structure of Oct4-Soc2-UTF1 complex
To Be Published
8I9M
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BU of 8i9m by Molmil
The RAGE and HMGB1 complex
Descriptor: Advanced glycosylation end product-specific receptor, High mobility group protein B1
Authors:Han, C.W, Kim, H.J.
Deposit date:2023-02-07
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (5.19 Å)
Cite:The RAGE and HMGB1 complex
To Be Published
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