7LBW

Crystal structure of TFAM (mitochondrial transcription factor A) bridging two non-sequence specific DNA substrates

Summary for 7LBW

• Entry DOI: 10.2210/pdb7lbw/pdb
• Descriptor: Transcription factor A, mitochondrial, DNA (5'-D(P*TP*AP*GP*CP*CP*TP*TP*TP*CP*TP*AP*TP*TP*AP*GP*CP*TP*CP*TP*TP*AP*G)-3'), 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: mitochondrial transcription, transcription initiation, mtdna, promoter recognition, dna bending, hmg box, mtdna packaging, transcription, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 76592.72

Authors

Choi, W.S.,Garcia-Diaz, M. (deposition date: 2021-01-09, release date: 2022-01-19, Last modification date: 2023-10-18)

• Primary citation: Choi, W.S.,Garcia-Diaz, M.; A minimal motif for sequence recognition by mitochondrial transcription factor A (TFAM).; Nucleic Acids Res., 50:322-332, 2022; PubMed: 34928349; DOI: 10.1093/nar/gkab1230

Experimental method

X-RAY DIFFRACTION (2.84 Å)