7LBW

Crystal structure of TFAM (mitochondrial transcription factor A) bridging two non-sequence specific DNA substrates

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transcription factor A, mitochondrial	polymer	204	24450.2	2	UniProt (Q00059) Pfam (PF00505) Pfam (PF09011)	Homo sapiens (Human)	mtTFA,Mitochondrial transcription factor 1,MtTF1,Transcription factor 6,TCF-6,Transcription factor 6-like 2
2	C, E (C, E)	DNA (5'-D(P*TP*AP*GP*CP*CP*TP*TP*TP*CP*TP*AP*TP*TP*AP*GP*CP*TP*CP*TP*TP*AP*G)-3')	polymer	22	6683.3	2		synthetic construct
3	D, F (D, F)	DNA (5'-D(P*TP*AP*GP*CP*CP*TP*TP*TP*CP*TP*AP*TP*TP*AP*GP*CP*TP*CP*TP*TP*AP*G)-3')	polymer	22	6817.5	2		synthetic construct
4	G, H, J, K, L... (A, B, C)	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
5	I, M, N (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	3	Chemie (PEG)
6	P, Q, R, S, T... (A, B, C, D, E...)	water	water		18.0	223	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	75901.9
Non-Polymers*	Number of molecules	9
	Total formula weight	690.8
All*	Total formula weight	76592.7

*Water molecules are not included.