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6TYF	Crystal structure of MTB sigma L transcription initiation complex with 6 nt long RNA primer Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Molodtsov, V, Ebright, R.H. Deposit date: 2019-08-08 Release date: 2020-03-11 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.8 Å) Cite: RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
6TYG	Crystal structure of MTB sigma L transcription initiation complex with 9 nt long RNA primer Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Molodtsov, V, Ebright, R.H. Deposit date: 2019-08-08 Release date: 2020-03-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.5 Å) Cite: RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
6TYE	Crystal structure of MTB sigma L transcription initiation complex with 5 nt long RNA primer Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Molodtsov, V, Ebright, R.H. Deposit date: 2019-08-08 Release date: 2020-03-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.79 Å) Cite: RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
5X21	Crystal structure of Thermus thermophilus transcription initiation complex with GpA and pseudouridimycin (PUM) Descriptor: (1S)-1,4-anhydro-5-[(N-carbamimidoylglycyl-N~2~-hydroxy-L-glutaminyl)amino]-5-deoxy-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zhang, Y, Ebright, R. Deposit date: 2017-01-29 Release date: 2017-07-05 Last modified: 2022-10-12 Method: X-RAY DIFFRACTION (3.323 Å) Cite: Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase. Cell, 169, 2017
5X22	Crystal structure of Thermus thermophilus transcription initiation complex with GpA and CMPcPP Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Zhang, Y, Ebright, R. Deposit date: 2017-01-29 Release date: 2017-07-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.35 Å) Cite: Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase. Cell, 169, 2017
7BZF	COVID-19 RNA-dependent RNA polymerase post-translocated catalytic complex Descriptor: Non-structural protein 7, Non-structural protein 8, RNA (31-MER), ... Authors: Wang, Q, Gao, Y, Ji, W, Mu, A, Rao, Z. Deposit date: 2020-04-27 Release date: 2020-06-03 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase. Cell, 182, 2020
7UBM	Transcription antitermination complex: "pre-engaged" Qlambda-loading complex Descriptor: Antitermination protein Q, DNA (52-MER), DNA (53-MER), ... Authors: Yin, Z, Ebright, R.H. Deposit date: 2022-03-15 Release date: 2022-09-28 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.13 Å) Cite: In transcription antitermination by Q lambda , NusA induces refolding of Q lambda to form a nozzle that extends the RNA polymerase RNA-exit channel. Proc.Natl.Acad.Sci.USA, 119, 2022
7UBN	Transcription antitermination complex: NusA-containing "engaged" Qlambda-loading complex Descriptor: Antitermination protein, DNA (52-MER), DNA (53-MER), ... Authors: Yin, Z, Ebright, R.H. Deposit date: 2022-03-15 Release date: 2022-09-28 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.36 Å) Cite: In transcription antitermination by Q lambda , NusA induces refolding of Q lambda to form a nozzle that extends the RNA polymerase RNA-exit channel. Proc.Natl.Acad.Sci.USA, 119, 2022
7XUE	Cryo-EM structure of HK022 putRNA-associated E.coli RNA polymerase elongation complex Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Hwang, S.H, Kang, J.Y. Deposit date: 2022-05-18 Release date: 2022-08-10 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA. Nat Commun, 13, 2022
7XUG	cryo-EM structure of HK022 putRNA-less E.coli RNA polymerase elongation complex Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Hwang, S, Kang, J.Y. Deposit date: 2022-05-18 Release date: 2022-08-10 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.57 Å) Cite: Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA. Nat Commun, 13, 2022
7XUI	Cryo-EM structure of sigma70 bound HK022 putRNA-associated E.coli RNA polymerase elongation complex Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Hwang, S, Kang, J.Y. Deposit date: 2022-05-18 Release date: 2022-08-10 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.61 Å) Cite: Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA. Nat Commun, 13, 2022
7Q4U	Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme octamer comprising sigma factor SigB Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Brodolin, K. Deposit date: 2021-11-02 Release date: 2022-11-16 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (4.39 Å) Cite: Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Nat Commun, 14, 2023
7C2K	COVID-19 RNA-dependent RNA polymerase pre-translocated catalytic complex Descriptor: Non-structural protein 7, Non-structural protein 8, RNA (29-MER), ... Authors: Wang, Q, Gao, Y, Ji, W, Mu, A, Rao, Z. Deposit date: 2020-05-07 Release date: 2020-06-03 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase. Cell, 182, 2020
3D9K	Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the Carboxy-Terminal Domain of RNA-Polymerase II Descriptor: CTD-PEPTIDE, RNA-binding protein 16, SULFATE ION Authors: Becker, R, Loll, B, Meinhart, A. Deposit date: 2008-05-27 Release date: 2008-06-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Snapshots of the RNA Processing Factor SCAF8 Bound to Different Phosphorylated Forms of the Carboxyl-terminal Domain of RNA Polymerase II. J.Biol.Chem., 283, 2008
7KHE	Escherichia coli RNA polymerase and rrnBP1 promoter pre-open complex with DksA/ppGpp Descriptor: CHAPSO, DNA (46-MER), DNA (54-MER), ... Authors: Shin, Y, Qayyum, M.Z, Murakami, K.S. Deposit date: 2020-10-21 Release date: 2020-12-09 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.58 Å) Cite: Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
7KHI	Escherichia coli RNA polymerase and rrnBP1 promoter complex with DksA/ppGpp Descriptor: CHAPSO, DNA (28-MER), DNA (36-MER), ... Authors: Shin, Y, Qayyum, M.Z, Murakami, K.S. Deposit date: 2020-10-21 Release date: 2020-10-28 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.62 Å) Cite: Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
3D9P	Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the Carboxy-Terminal Domain of RNA-Polymerase II Descriptor: CTD-PEPTIDE, RNA-binding protein 16, SULFATE ION Authors: Becker, R, Loll, B, Meinhart, A. Deposit date: 2008-05-27 Release date: 2008-06-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Snapshots of the RNA Processing Factor SCAF8 Bound to Different Phosphorylated Forms of the Carboxyl-terminal Domain of RNA Polymerase II. J.Biol.Chem., 283, 2008
6GVV	Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus Descriptor: GLYCEROL, RNA polymerase 3D Authors: Verdaguer, N, Ferrer Orta, C. Deposit date: 2018-06-21 Release date: 2018-08-01 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis. J.Virol., 92, 2018
3D9J	Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the Carboxy-Terminal Domain of RNA-Polymerase II Descriptor: AMMONIUM ION, GLYCEROL, RNA-binding protein 16, ... Authors: Becker, R, Loll, B, Meinhart, A. Deposit date: 2008-05-27 Release date: 2008-06-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Snapshots of the RNA Processing Factor SCAF8 Bound to Different Phosphorylated Forms of the Carboxyl-terminal Domain of RNA Polymerase II. J.Biol.Chem., 283, 2008
3D9N	Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the Carboxy-Terminal Domain of RNA-Polymerase II Descriptor: CTD-PEPTIDE, RNA-binding protein 16, SULFATE ION Authors: Becker, R, Loll, B, Meinhart, A. Deposit date: 2008-05-27 Release date: 2008-06-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Snapshots of the RNA Processing Factor SCAF8 Bound to Different Phosphorylated Forms of the Carboxyl-terminal Domain of RNA Polymerase II. J.Biol.Chem., 283, 2008
3D9I	Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the Carboxy-Terminal Domain of RNA-Polymerase II Descriptor: AMMONIUM ION, GLYCEROL, RNA-binding protein 16, ... Authors: Becker, R, Loll, B, Meinhart, A. Deposit date: 2008-05-27 Release date: 2008-06-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.907 Å) Cite: Snapshots of the RNA Processing Factor SCAF8 Bound to Different Phosphorylated Forms of the Carboxyl-terminal Domain of RNA Polymerase II. J.Biol.Chem., 283, 2008
5Y6Z	Crystal structure of the coxsackievirus A16 polymerase elongation complex Descriptor: GLYCEROL, Genome polyprotein, MAGNESIUM ION, ... Authors: Bi, P, Shu, B, Gong, P. Deposit date: 2017-08-15 Release date: 2017-12-27 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of the coxsackievirus A16 RNA-dependent RNA polymerase elongation complex reveals novel features in motif A dynamics Virol Sin, 32, 2017
7EEI	Structure of Rift Valley fever virus RNA-dependent RNA polymerase Descriptor: Replicase Authors: Wang, X, Hu, C.X. Deposit date: 2021-03-18 Release date: 2021-11-17 Last modified: 2022-03-16 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structure of Rift Valley Fever Virus RNA-Dependent RNA Polymerase. J.Virol., 96, 2022
3D9O	Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the Carboxy-Terminal Domain of RNA-Polymerase II Descriptor: AMMONIUM ION, CTD-PEPTIDE, RNA-binding protein 16, ... Authors: Becker, R, Loll, B, Meinhart, A. Deposit date: 2008-05-27 Release date: 2008-06-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Snapshots of the RNA Processing Factor SCAF8 Bound to Different Phosphorylated Forms of the Carboxyl-terminal Domain of RNA Polymerase II. J.Biol.Chem., 283, 2008
3D9L	Snapshots of the RNA processing factor SCAF8 bound to different phosphorylated forms of the Carboxy-Terminal Domain of RNA-Polymerase II Descriptor: ACETATE ION, CTD-PEPTIDE, GLYCEROL, ... Authors: Becker, R, Loll, B, Meinhart, A. Deposit date: 2008-05-27 Release date: 2008-06-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Snapshots of the RNA Processing Factor SCAF8 Bound to Different Phosphorylated Forms of the Carboxyl-terminal Domain of RNA Polymerase II. J.Biol.Chem., 283, 2008

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