6TYF

Crystal structure of MTB sigma L transcription initiation complex with 6 nt long RNA primer

Summary for 6TYF

Entry DOI	10.2210/pdb6tyf/pdb
Descriptor	DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (8 entities in total)
Functional Keywords	transcription, tuberculosis, initiation, sigma finger displacement
Biological source	Mycobacterium tuberculosis More
Total number of polymer chains	9
Total formula weight	400003.02
Authors	Molodtsov, V.,Ebright, R.H. (deposition date: 2019-08-08, release date: 2020-03-11, Last modification date: 2024-03-13)
Primary citation	Li, L.,Molodtsov, V.,Lin, W.,Ebright, R.H.,Zhang, Y. RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117:5801-5809, 2020 Cited by PubMed: 32127479 DOI: 10.1073/pnas.1920747117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.8 Å)

Structure validation