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6P4A
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BU of 6p4a by Molmil
HyHEL10 Fab complexed with hen egg lysozyme carrying two mutations (HEL2x-rigid): R21Q and R73E
Descriptor: HyHEL10 Fab heavy chain, HyHEL10 Fab light chain, Lysozyme C
Authors:Langley, D.B, Christ, D.
Deposit date:2019-05-27
Release date:2020-05-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OKQ
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BU of 6okq by Molmil
Crystal structure of the SF12 Fab
Descriptor: SF12 Fab Heavy Chain,SF12 Fab Heavy Chain, SF12 Fab Light Chain,SF12 Fab Light Chain
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2019-04-14
Release date:2019-06-05
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Immunity, 50, 2019
6OGE
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BU of 6oge by Molmil
Cryo-EM structure of Her2 extracellular domain-Trastuzumab Fab-Pertuzumab Fab complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab FAB HEAVY CHAIN, Pertuzumab FAB LIGHT CHAIN, ...
Authors:Hao, Y, Yu, X, Bai, Y, Huang, X.
Deposit date:2019-04-02
Release date:2019-05-15
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.36 Å)
Cite:Cryo-EM Structure of HER2-trastuzumab-pertuzumab complex.
Plos One, 14, 2019
6OKP
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BU of 6okp by Molmil
B41 SOSIP.664 in complex with the silent-face antibody SF12 and V3-targeting antibody 10-1074
Descriptor: 10-1074 Heavy Chain,10-1074 Heavy Chain, 10-1074 Light Chain,10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2019-04-14
Release date:2019-06-05
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Immunity, 50, 2019
6OOR
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BU of 6oor by Molmil
Structure of 1B1 bound to mouse CD1d
Descriptor: Antibody 1B1 Heavy chain, Antibody 1B1 Light chain, Antigen-presenting glycoprotein CD1d1, ...
Authors:Ying, G, Zajonc, D.M.
Deposit date:2019-04-23
Release date:2019-07-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis of NKT cell inhibition using the T-cell receptor-blocking anti-CD1d antibody 1B1.
J.Biol.Chem., 294, 2019
5E9D
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BU of 5e9d by Molmil
RD-1 Mart-1 High bound to Mart-1 decameric peptide (ELA) in complex with HLA-A2
Descriptor: A6-TCR Valpha, A6-TCR Vbeta, Beta-2-microglobulin, ...
Authors:Singh, N.K, Baker, B.M.
Deposit date:2015-10-15
Release date:2016-06-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:An Engineered Switch in T Cell Receptor Specificity Leads to an Unusual but Functional Binding Geometry.
Structure, 24, 2016
5ESV
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BU of 5esv by Molmil
Crystal Structure of Broadly Neutralizing Antibody CH03, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade C Superinfecting Strain of Donor CAP256.
Descriptor: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase,Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Yang, M, Kwong, P.D.
Deposit date:2015-11-17
Release date:2015-12-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.105 Å)
Cite:Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.
Nat.Struct.Mol.Biol., 23, 2016
5EWI
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BU of 5ewi by Molmil
Crystal Structure of the Human Fab VRC38.01, an HIV-1 V1V2-Directed Neutralizing Antibody Isolated from Donor N90
Descriptor: VRC38.01 Heavy Chain, VRC38.01 Light Chain
Authors:Gorman, J, Kwong, P.D.
Deposit date:2015-11-20
Release date:2016-11-23
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.5996 Å)
Cite:Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.
Immunity, 46, 2017
5FKA
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BU of 5fka by Molmil
Crystal structure of staphylococcal enterotoxin E in complex with a T cell receptor
Descriptor: STAPHYLOCOCCAL ENTEROTOXIN E, T CELL RECEPTOR ALPHA CHAIN, T CELL RECEPTOR BETA CHAIN, ...
Authors:Rodstrom, K.E.J, Regenthal, P, Lindkvist-Petersson, K.
Deposit date:2015-10-15
Release date:2016-05-25
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Two Common Structural Motifs for Tcr Recognition by Staphylococcal Enterotoxins.
Sci.Rep., 6, 2016
5EU6
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BU of 5eu6 by Molmil
HLA Class I antigen
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Bianchi, V, Cole, D.K, Sewell, A.K.
Deposit date:2015-11-18
Release date:2016-03-02
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
J.Biol.Chem., 291, 2016
5FK9
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BU of 5fk9 by Molmil
Crystal structure of staphylococcal enterotoxin A F47A mutant in complex with a T cell receptor
Descriptor: ENTEROTOXIN TYPE A, T CELL RECEPTOR ALPHA CHAIN, T CELL RECEPTOR BETA CHAIN
Authors:Rodstrom, K.E.J, Regenthal, P, Lindkvist-Petersson, K.
Deposit date:2015-10-15
Release date:2016-05-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Two Common Structural Motifs for Tcr Recognition by Staphylococcal Enterotoxins
Sci.Rep., 6, 2016
5E6I
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BU of 5e6i by Molmil
Crystal structure of TCR PF8 in complex with flu MP(58-66) epitope presented by HLA-A2
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Gao, M, Mariuzza, R.
Deposit date:2015-10-09
Release date:2016-10-19
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal structure of TCR PF8 in complex with flu MP(58-66) epitope presented by HLA-A2
To Be Published
5HYJ
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BU of 5hyj by Molmil
1E6 TCR in Complex with HLA-A02 carrying AQWGPDPAAA
Descriptor: ALA-GLN-TRP-GLY-PRO-ASP-PRO-ALA-ALA-ALA, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
Deposit date:2016-02-01
Release date:2016-05-04
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:A "hotspot" for autoimmune T cells in type 1 diabetes.
J.Clin.Invest., 126, 2016
6D78
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BU of 6d78 by Molmil
The complex between high-affinity TCR DMF5(alpha-D26Y,beta-L98W) and human Class I MHC HLA-A2 with the bound MART-1(27-35)peptide
Descriptor: Beta-2-microglobulin, DMF5 alpha chain,DMF5 alpha chain, DMF5 beta chain,DMF5 beta chain, ...
Authors:Hellman, L.M, Singh, N.K.
Deposit date:2018-04-24
Release date:2019-04-03
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.347 Å)
Cite:Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.
Mol. Ther., 27, 2019
6DC3
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BU of 6dc3 by Molmil
RSV prefusion F bound to RSD5 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab RSD5-Germline Heavy Chain, Fab RSD5-Germline Light Chain, ...
Authors:Battles, M.B, McLellan, J.S, Jones, H.J.
Deposit date:2018-05-04
Release date:2019-07-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.501 Å)
Cite:Alternative conformations of a major antigenic site on RSV F.
Plos Pathog., 15, 2019
6DC4
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BU of 6dc4 by Molmil
RSV-neutralizing human antibody AM22
Descriptor: 1,2-ETHANEDIOL, Fab AM22 Heavy Chain, Fab AM22 Light Chain
Authors:Jones, H.G, McLellan, J.S.
Deposit date:2018-05-04
Release date:2019-07-10
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Alternative conformations of a major antigenic site on RSV F.
Plos Pathog., 15, 2019
6DID
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BU of 6did by Molmil
HIV Env BG505 SOSIP with polyclonal Fabs from immunized rabbit #3417 post-boost#1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Turner, H.L, Cottrell, C.A, Oyen, D, Wilson, I.A, Ward, A.B.
Deposit date:2018-05-23
Release date:2018-09-05
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.71 Å)
Cite:Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization.
Immunity, 49, 2018
6DKJ
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BU of 6dkj by Molmil
human GIPR ECD and Fab complex
Descriptor: 1,2-ETHANEDIOL, Fab heavy chain, Fab light chain, ...
Authors:Min, X, Wang, Z.
Deposit date:2018-05-29
Release date:2019-05-08
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models.
Sci Transl Med, 10, 2018
6E9I
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BU of 6e9i by Molmil
The crystal structure of bovine ultralong antibody BOV-4
Descriptor: Bovine ultralong antibody BOV-4 heavy chain, Bovine ultralong antibody BOV-4 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E4Y
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BU of 6e4y by Molmil
Anti-PCSK9 fab 6E2 bound to the N-terminal peptide from PCSK9, unmodified
Descriptor: 6E2 heavy chain, 6E2 light chain, CHLORIDE ION, ...
Authors:Ultsch, M.H, Kirchhofer, D.K.
Deposit date:2018-07-18
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Identification of a Helical Segment within the Intrinsically Disordered Region of the PCSK9 Prodomain.
J. Mol. Biol., 431, 2019
6E4X
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BU of 6e4x by Molmil
Human antibody S5V2-29 in complex with influenza hemagglutinin A/Texas/50/2012 (H3N2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hemagglutinin, ...
Authors:McCarthy, K.R, Harrison, S.C.
Deposit date:2018-07-18
Release date:2019-05-22
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism.
Cell, 177, 2019
6E4Z
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BU of 6e4z by Molmil
Anti-PCSK9 fab 6E2 bound to the modified N-terminal peptide from PCSK9
Descriptor: 6E2 heavy chain, 6E2 light chain, Proprotein convertase subtilisin/kexin type 9, ...
Authors:Ultsch, M.H, Kirchhofer, D.K.
Deposit date:2018-07-18
Release date:2019-04-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Identification of a Helical Segment within the Intrinsically Disordered Region of the PCSK9 Prodomain.
J. Mol. Biol., 431, 2019
6E9H
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BU of 6e9h by Molmil
The crystal structure of bovine ultralong antibody BOV-3
Descriptor: Bovine ultralong antibody BOV-3 heavy chain, Bovine ultralong antibody BOV-3 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E9G
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BU of 6e9g by Molmil
The crystal structure of bovine ultralong antibody BOV-2
Descriptor: Bovine ultralong antibody BOV-2 heavy chain, Bovine ultralong antibody BOV-2 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.904 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019
6E9U
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BU of 6e9u by Molmil
The crystal structure of bovine ultralong antibody BOV-7
Descriptor: Bovine ultralong antibody BOV-7 heavy chain, Bovine ultralong antibody BOV-7 light chain
Authors:Dong, J, Crowe, J.E.
Deposit date:2018-08-01
Release date:2019-05-01
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains.
Front Immunol, 10, 2019

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