6BW9
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![BU of 6bw9 by Molmil](/molmil-images/mine/6bw9) | Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 1 | Descriptor: | Importin subunit alpha-3, Protein W | Authors: | Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | Deposit date: | 2017-12-14 | Release date: | 2018-07-04 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
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6MJB
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5NQV
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![BU of 5nqv by Molmil](/molmil-images/mine/5nqv) | Structure of the Arabidopsis Thaliana TOPLESS N-terminal domain | Descriptor: | EAR motif of IAA27, GLYCEROL, L(+)-TARTARIC ACID, ... | Authors: | Nanao, M.H, Arevalillo, M.R, Vinos-Poyo, T, Parcy, F, Dumas, R. | Deposit date: | 2017-04-21 | Release date: | 2017-07-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of the Arabidopsis TOPLESS corepressor provides insight into the evolution of transcriptional repression. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6N9J
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8J9G
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![BU of 8j9g by Molmil](/molmil-images/mine/8j9g) | CrtSPARTA hetero-dimer bound with guide-target, state 1 | Descriptor: | DNA (25-MER), MAGNESIUM ION, Piwi domain-containing protein, ... | Authors: | Li, Z.X, Guo, L.J, Huang, P.P, Xiao, Y.B, Chen, M.R. | Deposit date: | 2023-05-03 | Release date: | 2024-03-06 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system. Nat.Chem.Biol., 20, 2024
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8J8H
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![BU of 8j8h by Molmil](/molmil-images/mine/8j8h) | SPARTA monomer bound with guide-target, state 2 | Descriptor: | DNA (25-MER), MAGNESIUM ION, Piwi domain-containing protein, ... | Authors: | Li, Z.X, Guo, L.J, Huang, P.P, Xiao, Y.B, Chen, M.R. | Deposit date: | 2023-05-01 | Release date: | 2024-03-06 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system. Nat.Chem.Biol., 20, 2024
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6MLB
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8J9P
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![BU of 8j9p by Molmil](/molmil-images/mine/8j9p) | SPARTA dimer bound with guide-target | Descriptor: | DNA (25-MER), MAGNESIUM ION, Piwi domain-containing protein, ... | Authors: | Li, Z.X, Guo, L.J, Huang, P.P, Xiao, Y.B, Chen, M.R. | Deposit date: | 2023-05-04 | Release date: | 2024-03-06 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system. Nat.Chem.Biol., 20, 2024
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5NLI
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![BU of 5nli by Molmil](/molmil-images/mine/5nli) | Crystal structure of Zn2-E16V human ubiquitin (hUb) mutant adduct, from a solution 35 mM zinc acetate/10% v/v TFE/1.3 mM E16V hUb | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Polyubiquitin-C, ... | Authors: | Fermani, S, Falini, G. | Deposit date: | 2017-04-04 | Release date: | 2017-05-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Aggregation Pathways of Native-Like Ubiquitin Promoted by Single-Point Mutation, Metal Ion Concentration, and Dielectric Constant of the Medium. Chemistry, 24, 2018
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3MXN
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![BU of 3mxn by Molmil](/molmil-images/mine/3mxn) | Crystal structure of the RMI core complex | Descriptor: | BENZAMIDINE, RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 | Authors: | Hoadley, K.A, Xu, D, Xue, Y, Satyshur, K.A, Wang, W, Keck, J.L. | Deposit date: | 2010-05-07 | Release date: | 2010-09-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure and cellular roles of the RMI core complex from the bloom syndrome dissolvasome. Structure, 18, 2010
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6BWA
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![BU of 6bwa by Molmil](/molmil-images/mine/6bwa) | Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 2 | Descriptor: | Importin subunit alpha-3, Protein W | Authors: | Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | Deposit date: | 2017-12-14 | Release date: | 2018-07-04 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
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2AZZ
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![BU of 2azz by Molmil](/molmil-images/mine/2azz) | Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Taurocholate | Descriptor: | CALCIUM ION, CHLORIDE ION, Phospholipase A2, ... | Authors: | Pan, Y.H, Bahnson, B.J, Jain, M.K. | Deposit date: | 2005-09-12 | Release date: | 2006-11-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for bile salt inhibition of pancreatic phospholipase A2. J.Mol.Biol., 369, 2007
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2B03
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![BU of 2b03 by Molmil](/molmil-images/mine/2b03) | Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Taurochenodeoxycholate | Descriptor: | CALCIUM ION, Phospholipase A2, major isoenzyme, ... | Authors: | Pan, Y.H, Bahnson, B.J, Jain, M.K. | Deposit date: | 2005-09-12 | Release date: | 2006-11-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for bile salt inhibition of pancreatic phospholipase A2. J.Mol.Biol., 369, 2007
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5IZA
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![BU of 5iza by Molmil](/molmil-images/mine/5iza) | Protein-protein interaction | Descriptor: | ACE-GLY-GLY-GLU-ALA-LEU-ALA-TRP-NH2, Adenomatous polyposis coli protein | Authors: | Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. | Deposit date: | 2016-03-25 | Release date: | 2017-07-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat. Chem. Biol., 13, 2017
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6O1E
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![BU of 6o1e by Molmil](/molmil-images/mine/6o1e) | The crystal structure of human MORC3 ATPase-CW in complex with AMPPNP | Descriptor: | MAGNESIUM ION, MORC family CW-type zinc finger protein 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Klein, B.J, Zhang, Y, Kutateladze, T.G. | Deposit date: | 2019-02-19 | Release date: | 2019-03-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Mechanism for autoinhibition and activation of the MORC3 ATPase. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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2B01
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![BU of 2b01 by Molmil](/molmil-images/mine/2b01) | Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Taurochenodeoxycholate | Descriptor: | CALCIUM ION, CHLORIDE ION, Phospholipase A2, ... | Authors: | Pan, Y.H, Bahnson, B.J, Jain, M.K. | Deposit date: | 2005-09-12 | Release date: | 2006-11-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for bile salt inhibition of pancreatic phospholipase A2. J.Mol.Biol., 369, 2007
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6O2M
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3MZG
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![BU of 3mzg by Molmil](/molmil-images/mine/3mzg) | Crystal structure of a human prolactin receptor antagonist in complex with the extracellular domain of the human prolactin receptor | Descriptor: | CHLORIDE ION, Prolactin, Prolactin receptor, ... | Authors: | Kulkarni, M.V, Tettamanzi, M.C, Murphy, J.W, Keeler, C, Myszka, D.G, Chayen, N.E, Lolis, E.J, Hodsdon, M.E. | Deposit date: | 2010-05-12 | Release date: | 2010-09-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Two Independent Histidines, One in Human Prolactin and One in Its Receptor, Are Critical for pH-dependent Receptor Recognition and Activation. J.Biol.Chem., 285, 2010
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6NFY
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![BU of 6nfy by Molmil](/molmil-images/mine/6nfy) | Crystal structure of nonphosphorylated, HPK1 kinase domain in complex with sunitinib in the inactive state. | Descriptor: | Mitogen-activated protein kinase kinase kinase kinase 1, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide | Authors: | Johnson, E, McTigue, M, Cronin, C.N. | Deposit date: | 2018-12-21 | Release date: | 2019-05-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation. J.Biol.Chem., 294, 2019
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5N7C
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![BU of 5n7c by Molmil](/molmil-images/mine/5n7c) | Human TTR altered conformation from soaking in CuCl2. | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, COPPER (II) ION, ... | Authors: | Ciccone, L, Savko, M, Shepard, W, Stura, E.A. | Deposit date: | 2017-02-20 | Release date: | 2018-03-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Copper mediated amyloid-beta binding to Transthyretin. Sci Rep, 8, 2018
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5N62
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![BU of 5n62 by Molmil](/molmil-images/mine/5n62) | Human TTR crystals soaked in manganese chloride. | Descriptor: | MANGANESE (II) ION, Transthyretin | Authors: | Ciccone, L, Savko, M, Shepard, W, Stura, E.A. | Deposit date: | 2017-02-14 | Release date: | 2018-03-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Copper mediated amyloid-beta binding to Transthyretin. Sci Rep, 8, 2018
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8J84
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![BU of 8j84 by Molmil](/molmil-images/mine/8j84) | Short ago complexed with TIR-APAZ | Descriptor: | Piwi domain-containing protein, TIR domain-containing protein | Authors: | Guo, L.J, Huang, P.P, Li, Z.X, Xiao, Y.B, Chen, M.R. | Deposit date: | 2023-04-30 | Release date: | 2024-03-13 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system. Nat.Chem.Biol., 20, 2024
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7UJX
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![BU of 7ujx by Molmil](/molmil-images/mine/7ujx) | Structure of cAMP-dependent protein kinase using a MD-MX procedure, produced using 2.4 Angstrom data | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Wych, D.C, Aoto, P.C, Wall, M.E. | Deposit date: | 2022-03-31 | Release date: | 2022-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular-dynamics simulation methods for macromolecular crystallography. Acta Crystallogr D Struct Biol, 79, 2023
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7V0G
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![BU of 7v0g by Molmil](/molmil-images/mine/7v0g) | Structure of cAMP-dependent protein kinase using a MD-MX procedure, produced using 1.63 Angstrom data | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Wych, D.C, Aoto, P.C, Wall, M.E. | Deposit date: | 2022-05-10 | Release date: | 2022-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Molecular-dynamics simulation methods for macromolecular crystallography. Acta Crystallogr D Struct Biol, 79, 2023
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8AAN
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![BU of 8aan by Molmil](/molmil-images/mine/8aan) | The nucleoprotein complex of Rep protein with iteron containing dsDNA and DUE ssDNA. | Descriptor: | DNA (5'-D(*AP*TP*TP*TP*TP*TP*AP*T)-3'), DNA (5'-D(*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*T)-3'), DNA (5'-D(*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*T)-3'), ... | Authors: | Nowacka, M, Wegrzyn, K. | Deposit date: | 2022-07-01 | Release date: | 2023-09-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Rep protein accommodates together dsDNA and ssDNA which enables a loop-back mechanism to plasmid DNA replication initiation. Nucleic Acids Res., 51, 2023
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