6N9J

X-ray structure of a secreted C11 cysteine protease from Bacteroides thetaiotaomicron in complex with an irreversible peptide inhibitor

Summary for 6N9J

Entry DOI	10.2210/pdb6n9j/pdb
Descriptor	Clostripain-related protein, Covalently bound peptide inhibitor (3 entities in total)
Functional Keywords	c11 protease, secreted, covalent peptide inhibitor, microbiome, commensal, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) More
Total number of polymer chains	4
Total formula weight	85858.65
Authors	Wolan, D.W.,Gonzalez-Paez, G.E.,Roncase, E.J. (deposition date: 2018-12-03, release date: 2019-12-11, Last modification date: 2023-11-15)
Primary citation	Roncase, E.J.,Gonzalez-Paez, G.E.,Wolan, D.W. X-ray Structures of Two Bacteroides thetaiotaomicron C11 Proteases in Complex with Peptide-Based Inhibitors. Biochemistry, 58:1728-1737, 2019 Cited by PubMed: 30835452 DOI: 10.1021/acs.biochem.9b00098 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.17 Å)

Structure validation