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7TNN
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BU of 7tnn by Molmil
Complex GGNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
Authors:Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2022-01-21
Release date:2022-04-20
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNL
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Complex GNGN1 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
Authors:Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2022-01-21
Release date:2022-04-20
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNJ
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Complex NNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Descriptor: CYCLOTHIAZIDE, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
Authors:Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2022-01-21
Release date:2022-04-20
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNP
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BU of 7tnp by Molmil
Complex GGGG of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
Authors:Yelshanskaya, M.V, Sobolevsky, A.I.
Deposit date:2022-01-21
Release date:2022-04-20
Last modified:2022-05-18
Method:ELECTRON MICROSCOPY (3.96 Å)
Cite:Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
5CJ7
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BU of 5cj7 by Molmil
Human DNA polymerase lambda L431A mutant- MgdTTP binary and complex with 6 paired DNA
Descriptor: DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), DNA polymerase lambda, ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-07-14
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
3CSG
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BU of 3csg by Molmil
Crystal Structure of Monobody YS1(MBP-74)/Maltose Binding Protein Fusion Complex
Descriptor: Maltose-binding protein Monobody YS1 Fusion
Authors:Gilbreth, R.N, Koide, S.
Deposit date:2008-04-09
Release date:2008-07-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein-Protein Interfaces
J.Mol.Biol., 381, 2008
1E3W
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BU of 1e3w by Molmil
Rat brain 3-hydroxyacyl-CoA dehydrogenase binary complex with NADH and 3-keto butyrate
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETOACETIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Powell, A.J, Read, J.A, Brady, R.L.
Deposit date:2000-06-26
Release date:2001-05-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition of Structurally Diverse Substrates by Type II 3-Hydroxyacyl-Coa Dehydrogenase (Hadh II) Amyloid-Beta Binding Alcohol Dehydrogenase (Abad)
J.Mol.Biol., 303, 2000
1E3S
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BU of 1e3s by Molmil
Rat brain 3-hydroxyacyl-CoA dehydrogenase binary complex with NADH
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SHORT CHAIN 3-HYDROXYACYL-COA DEHYDROGENASE
Authors:Powell, A.J, Read, J.A, Banfield, M.J, Brady, R.L.
Deposit date:2000-06-22
Release date:2001-05-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition of Structurally Diverse Substrates by Type II 3-Hydroxyacyl-Coa Dehydrogenase (Hadh II) Amyloid-Beta Binding Alcohol Dehydrogenase (Abad)
J.Mol.Biol., 303, 2000
1QZY
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BU of 1qzy by Molmil
Human Methionine Aminopeptidase in complex with bengamide inhibitor LAF153 and cobalt
Descriptor: (E)-(2R,3R,4S,5R)-3,4,5-TRIHYDROXY-2-METHOXY-8,8-DIMETHYL-NON-6-ENOIC ACID ((3S,6R)-6-HYDROXY-2-OXO-AZEPAN-3-YL)-AMIDE, COBALT (II) ION, Methionine aminopeptidase 2, ...
Authors:Eck, M.J, Song, H.K, Morollo, A.
Deposit date:2003-09-18
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Proteomics-based target identification: bengamides as a new class of methionine aminopeptidase inhibitors.
J.Biol.Chem., 278, 2003
3D1K
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BU of 3d1k by Molmil
R/T intermediate quaternary structure of an antarctic fish hemoglobin in an alpha(CO)-beta(pentacoordinate) state
Descriptor: ACETYL GROUP, CARBON MONOXIDE, Hemoglobin subunit alpha-1, ...
Authors:Vitagliano, L, Vergara, A, Bonomi, G, Merlino, A, Mazzarella, L.
Deposit date:2008-05-06
Release date:2008-08-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Spectroscopic and crystallographic characterization of a tetrameric hemoglobin oxidation reveals structural features of the functional intermediate relaxed/tense state.
J.Am.Chem.Soc., 130, 2008
8CTA
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BU of 8cta by Molmil
Minimal 2:2 Ternary Complex between BI-224436 bound HIV-1 Integrase Catalytic Core Domain Dimer and Carboxy Terminal Domains
Descriptor: (2S)-tert-butoxy[4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl]acetic acid, 1,2-ETHANEDIOL, Integrase
Authors:Gupta, K, Van Duyne, G.D, Eilers, G, Bushman, F.D.
Deposit date:2022-05-13
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Structure of a HIV-1 IN-Allosteric inhibitor complex at 2.93 angstrom resolution: Routes to inhibitor optimization.
Plos Pathog., 19, 2023
1QJZ
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BU of 1qjz by Molmil
Three Dimensional Structure of Physalis Mottle Virus : Implications for the Viral Assembly
Descriptor: COAT PROTEIN
Authors:Krishna, S.S, Hiremath, C.N, Munshi, S.K, Prahadeeswaran, D, Sastri, M, Savithri, H.S, Murthy, M.R.N.
Deposit date:1999-07-07
Release date:1999-07-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Three Dimensional Structure of Physalis Movirus: Implications for the Viral Assembly
J.Mol.Biol., 289, 1999
1CSH
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BU of 1csh by Molmil
A very short hydrogen bond provides only moderate stabilization of an enzyme: inhibitor complex of citrate synthase
Descriptor: AMIDOCARBOXYMETHYLDETHIA COENZYME *A, CITRATE SYNTHASE, OXALOACETATE ION
Authors:Usher, K.C, Remington, S.J.
Deposit date:1994-03-07
Release date:1994-04-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A very short hydrogen bond provides only moderate stabilization of an enzyme-inhibitor complex of citrate synthase.
Biochemistry, 33, 1994
2SHK
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BU of 2shk by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF SHIKIMATE KINASE FROM ERWINIA CHRYSANTHEMI COMPLEXED WITH ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SHIKIMATE KINASE
Authors:Krell, T, Coggins, J.R, Lapthorn, A.J.
Deposit date:1997-10-27
Release date:1998-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallization and preliminary X-ray crystallographic analysis of shikimate kinase from Erwinia chrysanthemi.
Acta Crystallogr.,Sect.D, 53, 1997
1H4T
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BU of 1h4t by Molmil
Prolyl-tRNA synthetase from Thermus thermophilus complexed with L-proline
Descriptor: PROLINE, PROLYL-TRNA SYNTHETASE, ZINC ION
Authors:Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2001-05-14
Release date:2001-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase
J.Mol.Biol., 309, 2001
4C13
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BU of 4c13 by Molmil
x-ray crystal structure of Staphylococcus aureus MurE with UDP-MurNAc- Ala-Glu-Lys
Descriptor: CHLORIDE ION, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Ruane, K.M, Roper, D.I, Fulop, V, Barreteau, H, Boniface, A, Dementin, S, Blanot, D, Mengin-Lecreulx, D, Gobec, S, Dessen, A, Dowson, C.G, Lloyd, A.J.
Deposit date:2013-08-09
Release date:2013-10-02
Last modified:2021-03-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy.
Nat.Chem.Biol., 2021
3CSB
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BU of 3csb by Molmil
Crystal Structure of Monobody YSX1/Maltose Binding Protein Fusion Complex
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ...
Authors:Gilbreth, R.N, Koide, S.
Deposit date:2008-04-09
Release date:2008-07-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein-Protein Interfaces
J.Mol.Biol., 381, 2008
1HC7
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BU of 1hc7 by Molmil
Prolyl-tRNA synthetase from Thermus thermophilus
Descriptor: PROLYL-TRNA SYNTHETASE, ZINC ION
Authors:Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2001-04-26
Release date:2001-06-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase
J.Mol.Biol., 309, 2001
1JQN
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BU of 1jqn by Molmil
Crystal structure of E.coli phosphoenolpyruvate carboxylase in complex with Mn2+ and DCDP
Descriptor: 3,3-DICHLORO-2-PHOSPHONOMETHYL-ACRYLIC ACID, ASPARTIC ACID, MANGANESE (II) ION, ...
Authors:Matsumura, H, Kai, Y.
Deposit date:2001-08-07
Release date:2003-01-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structures of C4 form maize and quaternary complex of E. coli phosphoenolpyruvate carboxylases.
Structure, 10, 2002
1H4S
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BU of 1h4s by Molmil
Prolyl-tRNA synthetase from Thermus thermophilus complexed with tRNApro(CGG) and a prolyl-adenylate analogue
Descriptor: '5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE, PROLYL-TRNA SYNTHETASE, SULFATE ION, ...
Authors:Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2001-05-14
Release date:2001-06-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase
J.Mol.Biol., 309, 2001
8DSO
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BU of 8dso by Molmil
Structure of cIAP1, BTK and BCCov
Descriptor: (4S)-4-[2-(2-{4-[(2E)-4-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}-4-oxobut-2-en-1-yl]piperazin-1-yl}ethoxy)acetamido]-1-{(2S)-2-cyclohexyl-2-[(N-methyl-L-alanyl)amino]acetyl}-N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-L-prolinamide bound form, Baculoviral IAP repeat-containing protein 2, Tyrosine-protein kinase BTK, ...
Authors:Schiemer, J.S, Calabrese, M.F.
Deposit date:2022-07-22
Release date:2023-03-08
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.334 Å)
Cite:A covalent BTK ternary complex compatible with targeted protein degradation.
Nat Commun, 14, 2023
7U8P
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BU of 7u8p by Molmil
Structure of porcine kidney V-ATPase with SidK, Rotary State 1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H+ transporting accessory protein 1, ...
Authors:Tan, Y.Z, Keon, K.A.
Deposit date:2022-03-09
Release date:2022-07-06
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7.
Life Sci Alliance, 5, 2022
7U8R
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BU of 7u8r by Molmil
Structure of porcine kidney V-ATPase with SidK, Rotary State 3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H+ transporting accessory protein 1, ...
Authors:Tan, Y.Z, Keon, K.A.
Deposit date:2022-03-09
Release date:2022-07-06
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7.
Life Sci Alliance, 5, 2022
3DRC
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BU of 3drc by Molmil
INVESTIGATION OF THE FUNCTIONAL ROLE OF TRYPTOPHAN-22 IN ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE BY SITE-DIRECTED MUTAGENESIS
Descriptor: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
Authors:Oatley, S.J, Kraut, J.
Deposit date:1992-09-22
Release date:1994-01-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Investigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
Biochemistry, 30, 1991
7U8Q
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BU of 7u8q by Molmil
Structure of porcine kidney V-ATPase with SidK, Rotary State 2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H+ transporting accessory protein 1, ...
Authors:Tan, Y.Z, Keon, K.A.
Deposit date:2022-03-09
Release date:2022-07-06
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7.
Life Sci Alliance, 5, 2022

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