1H4T

Prolyl-tRNA synthetase from Thermus thermophilus complexed with L-proline

Summary for 1H4T

• Entry DOI: 10.2210/pdb1h4t/pdb
• Related: 1H4Q 1H4S 1HC7
• Descriptor: PROLYL-TRNA SYNTHETASE, PROLINE, ZINC ION, ... (4 entities in total)
• Functional Keywords: aminoacyl-trna synthetase, atp + l-proline + trna(pro) amp + ppi + l-prolyl-trna(pro), class ii aminoacyl-trna synthetase
• Biological source: THERMUS THERMOPHILUS
• Total number of polymer chains: 4
• Total formula weight: 218974.02

Authors

Yaremchuk, A.,Tukalo, M.,Cusack, S. (deposition date: 2001-05-14, release date: 2001-06-18, Last modification date: 2023-12-13)

• Primary citation: Yaremchuk, A.,Tukalo, M.,Grotli, M.,Cusack, S.; A Succession of Substrate Induced Conformational Changes Ensures the Amino Acid Specificity of Thermus Thermophilus Prolyl-tRNA Synthetase: Comparison with Histidyl-tRNA Synthetase; J.Mol.Biol., 309:989-, 2001; PubMed: 11399074; DOI: 10.1006/JMBI.2001.4712

Experimental method

X-RAY DIFFRACTION (2.9 Å)