7SXN
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![BU of 7sxn by Molmil](/molmil-images/mine/7sxn) | Orb2A residues 1-9 MYNKFVNFI | Descriptor: | Orb2A residues 1-9 MYNKFVNFI | Authors: | Bowler, J.T, Sawaya, M.R, Boyer, D.R, Cascio, D, Eisenberg, D.S. | Deposit date: | 2021-11-23 | Release date: | 2022-10-05 | Last modified: | 2024-05-22 | Method: | ELECTRON CRYSTALLOGRAPHY (1.05 Å) | Cite: | Micro-electron diffraction structure of the aggregation-driving N terminus of Drosophila neuronal protein Orb2A reveals amyloid-like beta-sheets. J.Biol.Chem., 298, 2022
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1BOD
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![BU of 1bod by Molmil](/molmil-images/mine/1bod) | THE SOLUTION STRUCTURES OF MUTANT CALBINDIN D9K'S, AS DETERMINED BY NMR, SHOW THAT THE CALCIUM BINDING SITE CAN ADOPT DIFFERENT FOLDS | Descriptor: | CALBINDIN D9K | Authors: | Johansson, C, Ullner, M, Drakenberg, T. | Deposit date: | 1993-04-23 | Release date: | 1993-10-31 | Last modified: | 2024-04-10 | Method: | SOLUTION NMR | Cite: | The solution structures of mutant calbindin D9k's, as determined by NMR, show that the calcium-binding site can adopt different folds. Biochemistry, 32, 1993
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1YG9
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![BU of 1yg9 by Molmil](/molmil-images/mine/1yg9) | The structure of mutant (N93Q) of bla g 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aspartic protease Bla g 2, ... | Authors: | Li, M, Gustchina, A, Wuenschmann, S, Pomes, A, Wlodawer, A. | Deposit date: | 2005-01-04 | Release date: | 2005-03-22 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal structure of cockroach allergen Bla g 2, an unusual zinc binding aspartic protease with a novel mode of self-inhibition. J.Mol.Biol., 348, 2005
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6ZUL
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![BU of 6zul by Molmil](/molmil-images/mine/6zul) | Crystal structure of dimethylated RSL in complex with cucurbit[7]uril and zinc | Descriptor: | Fucose-binding lectin protein, GLYCEROL, SODIUM ION, ... | Authors: | Guagnini, F, Engilberge, S, Flood, R.J, Ramberg, K.O, Crowley, P.B. | Deposit date: | 2020-07-23 | Release date: | 2020-11-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Metal-Mediated Protein-Cucurbituril Crystalline Architectures Cryst.Growth Des., 2020
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1CK7
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![BU of 1ck7 by Molmil](/molmil-images/mine/1ck7) | GELATINASE A (FULL-LENGTH) | Descriptor: | CALCIUM ION, CHLORIDE ION, PROTEIN (GELATINASE A), ... | Authors: | Morgunova, E, Tuuttila, A, Bergmann, U, Isupov, M, Lindqvist, Y, Schneider, G, Tryggvason, K. | Deposit date: | 1999-04-28 | Release date: | 1999-08-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed. Science, 284, 1999
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3G8B
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![BU of 3g8b by Molmil](/molmil-images/mine/3g8b) | T. thermophilus 16S rRNA G527 methyltransferase in complex with AdoMet in space group I222 | Descriptor: | Ribosomal RNA small subunit methyltransferase G, S-ADENOSYLMETHIONINE, SULFATE ION | Authors: | Demirci, H, Gregory, S.T, Belardinelli, R, Gualerzi, C, Dahlberg, A.E, Jogl, G. | Deposit date: | 2009-02-11 | Release date: | 2009-06-30 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG Rna, 15, 2009
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6ZUM
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![BU of 6zum by Molmil](/molmil-images/mine/6zum) | Crystal structure of dimethylated RSL-N23H (RSL-B3) in complex with cucurbit[7]uril and zinc | Descriptor: | ACETATE ION, Fucose-binding lectin protein, SODIUM ION, ... | Authors: | Guagnini, F, Engilberge, S, Flood, R.J, Ramberg, K.O, Crowley, P.B. | Deposit date: | 2020-07-23 | Release date: | 2020-11-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.589 Å) | Cite: | Metal-Mediated Protein-Cucurbituril Crystalline Architectures Cryst.Growth Des., 2020
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3G1E
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![BU of 3g1e by Molmil](/molmil-images/mine/3g1e) | X-ray crystal structure of coil 1A of human vimentin | Descriptor: | Vimentin | Authors: | Meier, M, Padilla, G.P, Herrmann, H, Wedig, T, Hergt, M, Patel, T.R, Stetefeld, J, Aebi, U, Burkhard, P. | Deposit date: | 2009-01-29 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Vimentin coil 1A-A molecular switch involved in the initiation of filament elongation. J.Mol.Biol., 390, 2009
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3GB6
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![BU of 3gb6 by Molmil](/molmil-images/mine/3gb6) | Structure of Giardia fructose-1,6-biphosphate aldolase D83A mutant in complex with fructose-1,6-bisphosphate | Descriptor: | 1,6-di-O-phosphono-D-fructose, Fructose-bisphosphate aldolase, ZINC ION | Authors: | Galkin, A, Herzberg, O. | Deposit date: | 2009-02-18 | Release date: | 2009-03-31 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into the substrate binding and stereoselectivity of giardia fructose-1,6-bisphosphate aldolase. Biochemistry, 48, 2009
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4QXS
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![BU of 4qxs by Molmil](/molmil-images/mine/4qxs) | Crystal structure of human FPPS in complex with WC01088 | Descriptor: | (2-{2-[(2S)-3-methylbutan-2-yl]-5-phenyl-1H-indol-3-yl}ethane-1,1-diyl)bis(phosphonic acid), Farnesyl pyrophosphate synthase, GLYCEROL, ... | Authors: | Park, J, Zielinski, M, Weiling, C, Tsantrizos, Y.S, Berghuis, A.M. | Deposit date: | 2014-07-21 | Release date: | 2015-02-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase. Bioorg.Med.Chem.Lett., 25, 2015
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4QY5
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![BU of 4qy5 by Molmil](/molmil-images/mine/4qy5) | Crystal structures of chimeric beta-lactamase cTEM-19m showing different conformations | Descriptor: | Beta-lactamase TEM,Beta-lactamase PSE-4, CHLORIDE ION, MAGNESIUM ION | Authors: | Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M. | Deposit date: | 2014-07-23 | Release date: | 2015-08-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | Crystal structures of chimeric beta-lactamase cTEM-19m showing different conformations To be Published
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1CR4
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![BU of 1cr4 by Molmil](/molmil-images/mine/1cr4) | CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE 4 PROTEIN OF BACTERIOPHAGE T7: COMPLEX WITH DTDP | Descriptor: | DNA PRIMASE/HELICASE, SULFATE ION, THYMIDINE-5'-DIPHOSPHATE | Authors: | Sawaya, M.R, Guo, S, Tabor, S, Richardson, C.C, Ellenberger, T. | Deposit date: | 1999-08-12 | Release date: | 1999-11-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7. Cell(Cambridge,Mass.), 99, 1999
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8QRH
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![BU of 8qrh by Molmil](/molmil-images/mine/8qrh) | Inactivated tick-borne encephalitis virus (TBEV) vaccine strain Sofjin-Chumakov | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, Small envelope protein M | Authors: | Moiseenko, A.V, Zhang, Y, Vorovitch, M, Ivanova, A, Liu, Z, Osolodkin, D.I, Egorov, A, Ishmukhametov, A, Sokolova, O.S. | Deposit date: | 2023-10-07 | Release date: | 2024-06-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The structure of inactivated mature tick-borne encephalitis virus at 3.0 angstrom resolution. Emerg Microbes Infect, 13, 2024
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1CR1
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![BU of 1cr1 by Molmil](/molmil-images/mine/1cr1) | CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE 4 PROTEIN OF BACTERIOPHAGE T7: COMPLEX WITH DTTP | Descriptor: | DNA PRIMASE/HELICASE, SULFATE ION, THYMIDINE-5'-TRIPHOSPHATE | Authors: | Sawaya, M.R, Guo, S, Tabor, S, Richardson, C.C, Ellenberger, T. | Deposit date: | 1999-08-12 | Release date: | 1999-11-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7. Cell(Cambridge,Mass.), 99, 1999
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6HZN
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![BU of 6hzn by Molmil](/molmil-images/mine/6hzn) | Crystal structure of human dermatan sulfate epimerase 1 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Hasan, M, Unge, J, Westergren-Thorsson, G, Ellervik, U, Mueller, U, Malmstrom, A, Tykesson, E. | Deposit date: | 2018-10-23 | Release date: | 2020-01-22 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms Chem Sci, 2020
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8W01
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![BU of 8w01 by Molmil](/molmil-images/mine/8w01) | |
5JSN
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![BU of 5jsn by Molmil](/molmil-images/mine/5jsn) | Bcl2-inhibitor complex | Descriptor: | Apoptosis regulator Bcl-2, Bcl2 inhibitor | Authors: | Shen, B.W, Stoddard, B.L. | Deposit date: | 2016-05-09 | Release date: | 2016-11-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer. Elife, 5, 2016
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7BCM
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![BU of 7bcm by Molmil](/molmil-images/mine/7bcm) | The DDR1 Kinase Domain Bound To SR302 | Descriptor: | Epithelial discoidin domain-containing receptor 1, ~{N}-[[4-[[(2~{S})-4-cyclohexyl-1-[[(3~{S})-1-methylsulfonylpiperidin-3-yl]amino]-1-oxidanylidene-butan-2-yl]carbamoyl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide | Authors: | Mathea, S, Chatterjee, D, Preuss, F, Roehm, S, Joerger, A, Knapp, S. | Deposit date: | 2020-12-20 | Release date: | 2021-03-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe. J.Med.Chem., 64, 2021
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3FWO
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![BU of 3fwo by Molmil](/molmil-images/mine/3fwo) | The large ribosomal subunit from Deinococcus radiodurans complexed with Methymycin | Descriptor: | (3R,4S,5S,7R,9E,11S,12R)-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA | Authors: | Auerbach, T, Mermershtain, I, Bashan, A, Davidovich, C, Rozenberg, H, Sherman, D.H, Yonath, A. | Deposit date: | 2009-01-19 | Release date: | 2010-01-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.71 Å) | Cite: | Structural basis for the antibacterial activity of the 12-membered-ring mono-sugar macrolide methymycin Biotechnologia, 1, 2009
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1CM0
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![BU of 1cm0 by Molmil](/molmil-images/mine/1cm0) | CRYSTAL STRUCTURE OF THE PCAF/COENZYME-A COMPLEX | Descriptor: | COENZYME A, P300/CBP ASSOCIATING FACTOR | Authors: | Clements, A, Rojas, J.R, Trievel, R.C, Wang, L, Berger, S.L, Marmorstein, R. | Deposit date: | 1999-05-12 | Release date: | 1999-07-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the histone acetyltransferase domain of the human PCAF transcriptional regulator bound to coenzyme A. EMBO J., 18, 1999
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6HVD
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![BU of 6hvd by Molmil](/molmil-images/mine/6hvd) | Human SLK bound to a maleimide inhibitor | Descriptor: | 1,2-ETHANEDIOL, 3-(1,3-benzothiazol-2-ylamino)-4-(2-methoxyphenyl)pyrrole-2,5-dione, STE20-like serine/threonine-protein kinase, ... | Authors: | Sorrell, F.J, Berger, B.T, Salah, E, Serafim, R.A.M, Savitsky, P.A, Krojer, T, Bailey, H.J, Pinkas, D, Burgess-Brown, N.A, von Delft, F, Knapp, S, Arrowsmith, C, Bountra, C, Edwards, A.M, Elkins, J.M. | Deposit date: | 2018-10-10 | Release date: | 2018-10-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Human SLK bound to a maleimide inhibitor To Be Published
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7BDQ
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![BU of 7bdq by Molmil](/molmil-images/mine/7bdq) | MAPK14 bound with SR300 | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Mitogen-activated protein kinase 14, ... | Authors: | Schroeder, M, Roehm, S, Joerger, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2020-12-22 | Release date: | 2021-03-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe. J.Med.Chem., 64, 2021
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8W04
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![BU of 8w04 by Molmil](/molmil-images/mine/8w04) | |
7BDO
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![BU of 7bdo by Molmil](/molmil-images/mine/7bdo) | MAPK14 bound with SR302 | Descriptor: | Mitogen-activated protein kinase 14, ~{N}-[[4-[[(2~{S})-4-cyclohexyl-1-[[(3~{S})-1-methylsulfonylpiperidin-3-yl]amino]-1-oxidanylidene-butan-2-yl]carbamoyl]phenyl]methyl]imidazo[1,2-a]pyridine-3-carboxamide | Authors: | Schroeder, M, Roehm, S, Joerger, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2020-12-22 | Release date: | 2021-03-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Development of a Selective Dual Discoidin Domain Receptor (DDR)/p38 Kinase Chemical Probe. J.Med.Chem., 64, 2021
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1CVJ
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![BU of 1cvj by Molmil](/molmil-images/mine/1cvj) | X-RAY CRYSTAL STRUCTURE OF THE POLY(A)-BINDING PROTEIN IN COMPLEX WITH POLYADENYLATE RNA | Descriptor: | 5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3', ADENOSINE MONOPHOSPHATE, POLYADENYLATE BINDING PROTEIN 1 | Authors: | Deo, R.C, Bonanno, J.B, Sonenberg, N, Burley, S.K. | Deposit date: | 1999-08-23 | Release date: | 1999-10-04 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Recognition of polyadenylate RNA by the poly(A)-binding protein. Cell(Cambridge,Mass.), 98, 1999
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