6HZN
Crystal structure of human dermatan sulfate epimerase 1
Summary for 6HZN
Entry DOI | 10.2210/pdb6hzn/pdb |
Descriptor | Dermatan-sulfate epimerase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | epimerase, golgi, glycosaminoglycans, chondroitin sulfate, dermatan sulfate, biosynthetic protein, isomerase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 89484.43 |
Authors | Hasan, M.,Unge, J.,Westergren-Thorsson, G.,Ellervik, U.,Mueller, U.,Malmstrom, A.,Tykesson, E. (deposition date: 2018-10-23, release date: 2020-01-22, Last modification date: 2024-11-13) |
Primary citation | Hasan, M.,Khakzad, H.,Happonen, L.,Sundin, A.,Unge, J.,Mueller, U.,Malmstrom, J.,Westergren-Thorsson, G.,Malmstrom, L.,Ellervik, U.,Malmstrom, A.,Tykesson, E. The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms Chem Sci, 2020 Cited by DOI: 10.1039/D0SC05971DPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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