6HZN
Crystal structure of human dermatan sulfate epimerase 1
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000269|PubMed:19004833, ECO:0000269|DOI:10.1039/D0SC05971D |
| Chain | Residue | Details |
| A | HIS205 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:19004833, ECO:0000269|DOI:10.1039/D0SC05971D |
| Chain | Residue | Details |
| A | TYR261 | |
| A | TYR473 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|DOI:10.1039/D0SC05971D, ECO:0007744|PDB:6HZN |
| Chain | Residue | Details |
| A | HIS452 | |
| A | GLU470 | |
| A | ASN481 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Critical for catalysis => ECO:0000269|PubMed:19004833 |
| Chain | Residue | Details |
| A | HIS450 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:19004833, ECO:0000269|DOI:10.1039/D0SC05971D, ECO:0007744|PDB:6HZN |
| Chain | Residue | Details |
| A | ASN183 | |
| A | ASN642 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine => ECO:0000269|PubMed:19004833, ECO:0000269|DOI:10.1039/D0SC05971D, ECO:0007744|PDB:6HZN |
| Chain | Residue | Details |
| A | ASN336 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|DOI:10.1039/D0SC05971D, ECO:0007744|PDB:6HZN |
| Chain | Residue | Details |
| A | ASN411 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) (paucimannose) asparagine => ECO:0000269|PubMed:19004833, ECO:0000269|DOI:10.1039/D0SC05971D, ECO:0007744|PDB:6HZN |
| Chain | Residue | Details |
| A | ASN648 |
