1ROW
| Structure of SSP-19, an MSP-domain protein like family member in Caenorhabditis elegans | Descriptor: | MSP-domain protein like family member | Authors: | Schormann, N, Symersky, J, Carson, M, Luo, M, Lin, G, Li, S, Qiu, S, Arabashi, A, Bunzel, B, Luo, D, Nagy, L, Gray, R, Luan, C.-H, Zhang, J, Lu, S, DeLucas, L, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2003-12-02 | Release date: | 2003-12-23 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of sperm-specific protein SSP-19 from Caenorhabditis elegans. Acta Crystallogr.,Sect.D, 60, 2004
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2RM0
| FBP28WW2 domain in complex with a PPPLIPPPP peptide | Descriptor: | Formin-1, Transcription elongation regulator 1 | Authors: | Ramirez-Espain, X, Ruiz, L, Martin-Malpartida, P, Oschkinat, H, Macias, M.J. | Deposit date: | 2007-09-06 | Release date: | 2007-11-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Characterization of a New Binding Motif and a Novel Binding Mode in Group 2 WW Domains J.Mol.Biol., 373, 2007
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2RLY
| FBP28WW2 domain in complex with PTPPPLPP peptide | Descriptor: | Formin-1, Transcription elongation regulator 1 | Authors: | Ramirez-Espain, X, Ruiz, L, Martin-Malpartida, P, Oschkinat, H, Macias, M.J. | Deposit date: | 2007-09-03 | Release date: | 2007-11-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Characterization of a New Binding Motif and a Novel Binding Mode in Group 2 WW Domains J.Mol.Biol., 373, 2007
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6M3Q
| Crystal structure of AnkB/beta4-spectrin complex | Descriptor: | Ankyrin-2, Spectrin beta chain | Authors: | Li, J, Chen, K, Zhu, R, Zhang, M. | Deposit date: | 2020-03-04 | Release date: | 2020-05-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.436 Å) | Cite: | Structural Basis Underlying Strong Interactions between Ankyrins and Spectrins. J.Mol.Biol., 432, 2020
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2MPM
| Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: the N-terminal Region of CCR3 Bound to CCL11/Eotaxin-1 | Descriptor: | CCR3, Eotaxin | Authors: | Millard, C.J, Ludeman, J.P, Canals, M, Bridgford, J.L, Hinds, M.G, Clayton, D.J, Christopoulos, A, Payne, R.J, Stone, M.J. | Deposit date: | 2014-05-26 | Release date: | 2014-12-10 | Method: | SOLUTION NMR | Cite: | Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: The N-Terminal Region of CCR3 Bound to CCL11/Eotaxin-1. Structure, 22, 2014
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2N62
| ddFLN5+110 | Descriptor: | gelation factor, secretion monitor chimera | Authors: | Cabrita, L.D, Cassaignau, A.M.E, Launay, H.M.M, Waudby, C.A, Camilloni, C, Robertson, A.L, Wang, X, Wlodarski, T, Wentink, A.S, Vendruscolo, M, Dobson, C.M, Christodoulou, J. | Deposit date: | 2015-08-10 | Release date: | 2016-03-02 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A structural ensemble of a ribosome-nascent chain complex during cotranslational protein folding. Nat.Struct.Mol.Biol., 23, 2016
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4E61
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2UYT
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2V7A
| Crystal structure of the T315I Abl mutant in complex with the inhibitor PHA-739358 | Descriptor: | MAGNESIUM ION, N-[(3E)-5-[(2R)-2-METHOXY-2-PHENYLACETYL]PYRROLO[3,4-C]PYRAZOL-3(5H)-YLIDENE]-4-(4-METHYLPIPERAZIN-1-YL)BENZAMIDE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 | Authors: | Modugno, M, Casale, E, Soncini, C, Rosettani, P, Colombo, R, Lupi, R, Rusconi, L, Fancelli, D, Carpinelli, P, Cameron, A.D, Isacchi, A, Moll, J. | Deposit date: | 2007-07-27 | Release date: | 2007-09-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of the T315I Abl Mutant in Complex with the Aurora Kinases Inhibitor Pha-739358. Cancer Res., 67, 2007
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2NMM
| Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409 | Descriptor: | 14 kDa phosphohistidine phosphatase, SULFATE ION | Authors: | Kuzin, A.P, Abashidze, M, Forouhar, F, Seetharaman, J, Kent, C, Fang, Y, Cunningham, K, Conover, K, Ma, L.C, Xiao, R, Acton, T, Montelione, G, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-10-22 | Release date: | 2007-01-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409 To be Published
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2RQ1
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6KLQ
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6KLP
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2K76
| Solution structure of a paralog-specific Mena binder by NMR | Descriptor: | pGolemi | Authors: | Link, N.M, Hunke, C, Eichler, J, Bayer, P. | Deposit date: | 2008-08-03 | Release date: | 2009-06-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The solution structure of pGolemi, a high affinity Mena EVH1 binding miniature protein, suggests explanations for paralog-specific binding to Ena/VASP homology (EVH) 1 domains. Biol.Chem., 390, 2009
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2V1Q
| Atomic-resolution structure of the yeast Sla1 SH3 domain 3 | Descriptor: | CHLORIDE ION, CYTOSKELETON ASSEMBLY CONTROL PROTEIN SLA1, PLATINUM (II) ION, ... | Authors: | Kursula, I, Kursula, P, Zou, P, Lehmann, F, Song, Y.H, Wilmanns, M. | Deposit date: | 2007-05-29 | Release date: | 2008-06-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural Genomics of Yeast SH3 Domains To be Published
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2KKW
| SLAS-micelle bound alpha-synuclein | Descriptor: | Alpha-synuclein | Authors: | Rao, J, Jao, C.C, Hegde, B, Langen, R, Ulmer, T.S. | Deposit date: | 2009-06-29 | Release date: | 2010-06-16 | Last modified: | 2024-05-01 | Method: | EPR, SOLUTION NMR | Cite: | A combinatorial NMR and EPR approach for evaluating the structural ensemble of partially folded proteins. J.Am.Chem.Soc., 132, 2010
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2NT2
| Crystal Structure of Slingshot phosphatase 2 | Descriptor: | Protein phosphatase Slingshot homolog 2, SULFATE ION | Authors: | Jung, S.K, Jeong, D.G, Yoon, T.S, Kim, J.H, Ryu, S.E, Kim, S.J. | Deposit date: | 2006-11-06 | Release date: | 2007-06-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of human slingshot phosphatase 2. Proteins, 68, 2007
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2N0A
| Atomic-resolution structure of alpha-synuclein fibrils | Descriptor: | Alpha-synuclein | Authors: | Tuttle, M.D, Comellas, G, Nieuwkoop, A.J, Covell, D.J, Berthold, D.A, Kloepper, K.D, Courtney, J.M, Kim, J.K, Schwieters, C.D, Lee, V.M, George, J.M, Rienstra, C.M. | Deposit date: | 2015-03-04 | Release date: | 2016-03-23 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Solid-state NMR structure of a pathogenic fibril of full-length human alpha-synuclein. Nat.Struct.Mol.Biol., 23, 2016
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5EOA
| Crystal structure of OPTN E50K mutant and TBK1 complex | Descriptor: | Optineurin, Serine/threonine-protein kinase TBK1 | Authors: | Li, F, Xie, X, Liu, J, Pan, L. | Deposit date: | 2015-11-10 | Release date: | 2016-09-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.503 Å) | Cite: | Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins. Nat Commun, 7, 2016
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5F4X
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5F5P
| Molecular Basis for Shroom2 Recognition by Rock1 | Descriptor: | CHLORIDE ION, Protein Shroom2, Rho-associated protein kinase 1 | Authors: | Zalewski, J.K, VanDemark, A.P, Heroux, A. | Deposit date: | 2015-12-04 | Release date: | 2016-10-19 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.568 Å) | Cite: | Structure of the Shroom-Rho Kinase Complex Reveals a Binding Interface with Monomeric Shroom That Regulates Cell Morphology and Stimulates Kinase Activity. J. Biol. Chem., 291, 2016
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5EOF
| Crystal structure of OPTN NTD and TBK1 CTD complex | Descriptor: | Optineurin, Serine/threonine-protein kinase TBK1 | Authors: | Li, F, Xie, X, Liu, J, Pan, L. | Deposit date: | 2015-11-10 | Release date: | 2016-09-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins. Nat Commun, 7, 2016
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6TXS
| The structure of the FERM domain and helical linker of human moesin bound to a CD44 peptide | Descriptor: | CD44 antigen, Moesin | Authors: | Bradshaw, W.J, Katis, V.L, Kelly, J.J, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | Deposit date: | 2020-01-14 | Release date: | 2020-01-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
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7P6X
| Cryo-Em structure of the hexameric RUVBL1-RUVBL2 in complex with ZNHIT2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 | Authors: | Llorca, O, Serna, M, Fernandez-Leiro, R. | Deposit date: | 2021-07-18 | Release date: | 2021-12-15 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8. Nucleic Acids Res., 50, 2022
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6TXQ
| The high resolution structure of the FERM domain and helical linker of human moesin | Descriptor: | ACETATE ION, Moesin | Authors: | Bradshaw, W.J, Katis, V.L, Kelly, J.J, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | Deposit date: | 2020-01-14 | Release date: | 2020-01-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease. J.Biol.Chem., 299, 2023
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