5F5P

Molecular Basis for Shroom2 Recognition by Rock1

Summary for 5F5P

• Entry DOI: 10.2210/pdb5f5p/pdb
• Related: 3THF 4L2W
• Descriptor: Protein Shroom2, Rho-associated protein kinase 1, CHLORIDE ION (3 entities in total)
• Functional Keywords: coiled-coil, complex, cytoskeleton, kinase, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 138410.09

Authors

Zalewski, J.K.,VanDemark, A.P.,Heroux, A. (deposition date: 2015-12-04, release date: 2016-10-19, Last modification date: 2023-09-27)

• Primary citation: Zalewski, J.K.,Mo, J.H.,Heber, S.,Heroux, A.,Gardner, R.G.,Hildebrand, J.D.,VanDemark, A.P.; Structure of the Shroom-Rho Kinase Complex Reveals a Binding Interface with Monomeric Shroom That Regulates Cell Morphology and Stimulates Kinase Activity.; J. Biol. Chem., 291:25364-25374, 2016; PubMed: 27758857; DOI: 10.1074/jbc.M116.738559

Experimental method

X-RAY DIFFRACTION (3.568 Å)