5F5P
Molecular Basis for Shroom2 Recognition by Rock1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, G, H (A, B, G, H) | Protein Shroom2 | polymer | 217 | 24481.7 | 4 | UniProt (Q13796) Pfam (PF08687) | Homo sapiens (Human) | Apical-like protein,Protein APXL |
| 2 | C, D, E, F (C, D, E, F) | Rho-associated protein kinase 1 | polymer | 86 | 10103.1 | 4 | UniProt (Q13464) | Homo sapiens (Human) | Renal carcinoma antigen NY-REN-35,Rho-associated,coiled-coil-containing protein kinase 1,coiled-coil-containing protein kinase I,ROCK-I,p160 ROCK-1,p160ROCK |
| 3 | I, J (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) |
Sequence modifications
A, B, G, H: 1427 - 1610 (UniProt: Q13796)
C, D, E, F: 834 - 913 (UniProt: Q13464)
| PDB | External Database | Details |
|---|---|---|
| Gly 1421 | - | expression tag |
| Ile 1422 | - | expression tag |
| Asp 1423 | - | expression tag |
| Pro 1424 | - | expression tag |
| Phe 1425 | - | expression tag |
| Thr 1426 | - | expression tag |
| His 1611 | - | expression tag |
| Ser 1612 | - | expression tag |
| Lys 1613 | - | expression tag |
| Arg 1614 | - | expression tag |
| Ala 1615 | - | expression tag |
| Ser 1616 | - | expression tag |
| Ser 1617 | - | expression tag |
| Asp 1618 | - | expression tag |
| Pro 1619 | - | expression tag |
| Ala 1620 | - | expression tag |
| Ala 1621 | - | expression tag |
| Asn 1622 | - | expression tag |
| Lys 1623 | - | expression tag |
| Ala 1624 | - | expression tag |
| Arg 1625 | - | expression tag |
| Lys 1626 | - | expression tag |
| Glu 1627 | - | expression tag |
| Ala 1628 | - | expression tag |
| Glu 1629 | - | expression tag |
| Leu 1630 | - | expression tag |
| Ala 1631 | - | expression tag |
| Ala 1632 | - | expression tag |
| Ala 1633 | - | expression tag |
| Thr 1634 | - | expression tag |
| Ala 1635 | - | expression tag |
| Glu 1636 | - | expression tag |
| Gln 1637 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 828 | - | expression tag |
| Ile 829 | - | expression tag |
| Asp 830 | - | expression tag |
| Pro 831 | - | expression tag |
| Phe 832 | - | expression tag |
| Thr 833 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 138339.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 138410.1 |
