2N0A
Atomic-resolution structure of alpha-synuclein fibrils
Summary for 2N0A
Entry DOI | 10.2210/pdb2n0a/pdb |
NMR Information | BMRB: 25518 |
Descriptor | Alpha-synuclein (1 entity in total) |
Functional Keywords | protein fibril, amyloid, parkinson's disease, structural protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytosol : P37840 |
Total number of polymer chains | 10 |
Total formula weight | 144761.08 |
Authors | Tuttle, M.D.,Comellas, G.,Nieuwkoop, A.J.,Covell, D.J.,Berthold, D.A.,Kloepper, K.D.,Courtney, J.M.,Kim, J.K.,Schwieters, C.D.,Lee, V.M.,George, J.M.,Rienstra, C.M. (deposition date: 2015-03-04, release date: 2016-03-23, Last modification date: 2024-05-15) |
Primary citation | Tuttle, M.D.,Comellas, G.,Nieuwkoop, A.J.,Covell, D.J.,Berthold, D.A.,Kloepper, K.D.,Courtney, J.M.,Kim, J.K.,Barclay, A.M.,Kendall, A.,Wan, W.,Stubbs, G.,Schwieters, C.D.,Lee, V.M.,George, J.M.,Rienstra, C.M. Solid-state NMR structure of a pathogenic fibril of full-length human alpha-synuclein. Nat.Struct.Mol.Biol., 23:409-415, 2016 Cited by PubMed: 27018801DOI: 10.1038/nsmb.3194 PDB entries with the same primary citation |
Experimental method | SOLID-STATE NMR |
Structure validation
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