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2LI3
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Structural and functional analysis of a novel potassium toxin argentinean scorpion Tityus trivittatus reveals a new kappa sub-family
Descriptor: Potassium channel toxin kappa-KTX3.1
Authors:Saucedo-Yanez, A, Del Rio-Portilla, F, Hernandez-Lopez, R.
Deposit date:2011-08-19
Release date:2012-01-11
Last modified:2012-04-25
Method:SOLUTION NMR
Cite:New Tricks of an Old Pattern: STRUCTURAL VERSATILITY OF SCORPION TOXINS WITH COMMON CYSTEINE SPACING.
J.Biol.Chem., 287, 2012
8W9O
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BU of 8w9o by Molmil
structure of AtHKT1;1 in KCl at 2.8 Angstroms resolution
Descriptor: POTASSIUM ION, Sodium transporter HKT1
Authors:Wang, J, Su, N, Guo, J.
Deposit date:2023-09-05
Release date:2024-02-14
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structures and ion transport mechanisms of plant high-affinity potassium transporters.
Mol Plant, 17, 2024
1RJI
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BU of 1rji by Molmil
Solution Structure of BmKX, a novel potassium channel blocker from the Chinese Scorpion Buthus martensi Karsch
Descriptor: potassium channel toxin KX
Authors:Cai, Z, Wu, J, Xu, Y, Wang, C.-G, Chi, C.-W, Shi, Y.
Deposit date:2003-11-19
Release date:2003-12-09
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:A novel short-chain peptide BmKX from the Chinese scorpion Buthus martensi karsch, sequencing, gene cloning and structure determination
Toxicon, 45, 2005
4G65
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BU of 4g65 by Molmil
Potassium transporter peripheral membrane component (trkA) from Vibrio vulnificus
Descriptor: CHLORIDE ION, SULFATE ION, TETRAETHYLENE GLYCOL, ...
Authors:Filippova, E.V, Wawrzak, Z, Skarina, T, Onopriyenko, O, Edwards, A, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-07-18
Release date:2012-08-15
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Potassium transporter peripheral membrane component (trkA) from Vibrio vulnificus.
To be Published
7NP4
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BU of 7np4 by Molmil
cAMP-bound rabbit HCN4 stabilized in LMNG-CHS detergent mixture
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Authors:Giese, H, Chaves-Sanjuan, A, Saponaro, A, Clarke, O, Bolognesi, M, Mancia, F, Hendrickson, W.A, Thiel, G, Santoro, B, Moroni, A.
Deposit date:2021-02-26
Release date:2021-08-11
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Gating movements and ion permeation in HCN4 pacemaker channels.
Mol.Cell, 81, 2021
1U4F
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Crystal Structure of Cytoplasmic Domains of IRK1 (Kir2.1) channel
Descriptor: Inward rectifier potassium channel 2
Authors:Pegan, S, Arrabit, C, Zhou, W, Kwiatkowski, W, Slesinger, P.A, Choe, S.
Deposit date:2004-07-24
Release date:2005-03-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification
Nat.Neurosci., 8, 2005
7YO3
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BU of 7yo3 by Molmil
Cryo-EM structure of human Slo1-LRRC26 complex with C4 symmetry
Descriptor: CALCIUM ION, Calcium-activated potassium channel subunit alpha-1, Leucine-rich repeat-containing protein 26, ...
Authors:Yamanouchi, D, Nureki, O.
Deposit date:2022-08-01
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for dual allosteric gating modulation of Slo1-LRRC channel complex
To Be Published
5WLX
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BU of 5wlx by Molmil
Solution structure of kappa-theraphotoxin-Aa1a
Descriptor: Kappa-theraphotoxin-Aa1a
Authors:Chin, Y.K.Y, Ma, L, King, G.F.
Deposit date:2017-07-28
Release date:2018-08-01
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target.
Biochem. Pharmacol., 158, 2018
5X0S
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BU of 5x0s by Molmil
Solution NMR structure of peptide toxin SsTx from Scolopendra subspinipes mutilans
Descriptor: SsTx
Authors:Wu, F, Luo, L, Qu, D, Zhang, L, Tian, C, Lai, R.
Deposit date:2017-01-23
Release date:2018-01-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Centipedes subdue giant prey by blocking KCNQ channels
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8I47
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BU of 8i47 by Molmil
Cryo-EM structure of nanodisc (PE:PS:PC) reconstituted GLIC at pH 5.5
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Proton-gated ion channel
Authors:Bharambe, N, Li, Z, Basak, S.
Deposit date:2023-01-18
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment.
Nat Commun, 15, 2024
6XIW
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Cryo-EM structure of the sodium leak channel NALCN-FAM155A complex
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kschonsak, M, Chua, H.C, Noland, C.L, Weidling, C, Clairfeuille, T, Bahlke, O.O, Ameen, A.O, Li, Z.R, Arthur, C.P, Ciferri, C, Pless, S.A, Payandeh, J.
Deposit date:2020-06-22
Release date:2020-07-29
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of the human sodium leak channel NALCN.
Nature, 587, 2020
6LEH
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Crystal structure of Autotaxin in complex with an inhibitor
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Nishimasu, H, Osamu, N.
Deposit date:2019-11-25
Release date:2020-03-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of PotentIn VivoAutotaxin Inhibitors that Bind to Both Hydrophobic Pockets and Channels in the Catalytic Domain.
J.Med.Chem., 63, 2020
5MRW
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BU of 5mrw by Molmil
Structure of the KdpFABC complex
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ...
Authors:Huang, C, Pedersen, B.P, Stokes, D.L.
Deposit date:2016-12-27
Release date:2017-06-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the potassium-importing KdpFABC membrane complex.
Nature, 546, 2017
6E2G
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BU of 6e2g by Molmil
Cryo-EM structure of rat TRPV6 in complex with Calmodulin
Descriptor: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 6
Authors:Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I.
Deposit date:2018-07-11
Release date:2018-08-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6.
Sci Adv, 4, 2018
6E2F
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BU of 6e2f by Molmil
Cryo-EM structure of human TRPV6 in complex with Calmodulin
Descriptor: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 6
Authors:Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I.
Deposit date:2018-07-11
Release date:2018-08-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6.
Sci Adv, 4, 2018
6MBA
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BU of 6mba by Molmil
Crystal Structure of Human Nav1.4 CTerminal Domain in Complex with apo Calmodulin
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CARBONATE ION, ...
Authors:Yoder, J, Gabelli, S.B, Amzel, L.M.
Deposit date:2018-08-29
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif.
Nat Commun, 10, 2019
7F3F
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CryoEM structure of human Kv4.2-KChIP1 complex
Descriptor: Isoform 2 of Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2
Authors:Kise, Y, Nureki, O.
Deposit date:2021-06-16
Release date:2021-10-13
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of gating modulation of Kv4 channel complexes.
Nature, 599, 2021
6FEG
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BU of 6feg by Molmil
Solution Structure of CaM/Kv7.2-hAB Complex
Descriptor: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2,Potassium voltage-gated channel subfamily KQT member 2
Authors:Bernardo-Seisdedos, G, Villarroel, A, Millet, O.
Deposit date:2018-01-02
Release date:2018-02-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis and energy landscape for the Ca2+gating and calmodulation of the Kv7.2 K+channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7E83
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BU of 7e83 by Molmil
CryoEM structure of the human Kv4.2-KChIP1 complex, intracellular region
Descriptor: Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2
Authors:Kise, Y, Nureki, O.
Deposit date:2021-02-28
Release date:2021-10-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of gating modulation of Kv4 channel complexes.
Nature, 599, 2021
7E84
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BU of 7e84 by Molmil
CryoEM structure of human Kv4.2-KChIP1 complex
Descriptor: Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2
Authors:Kise, Y, Nureki, O.
Deposit date:2021-02-28
Release date:2021-10-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of gating modulation of Kv4 channel complexes.
Nature, 599, 2021
6FEH
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BU of 6feh by Molmil
Solution Structure of CaM/Kv7.2-hAB Complex
Descriptor: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2,Potassium voltage-gated channel subfamily KQT member 2
Authors:Bernardo-Seisdedos, G, Villarroel, A, Millet, O.
Deposit date:2018-01-02
Release date:2018-02-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis and energy landscape for the Ca2+gating and calmodulation of the Kv7.2 K+channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7E8E
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BU of 7e8e by Molmil
CryoEM structure of human Kv4.2-DPP6S-KChIP1 complex, transmembrane and intracellular region
Descriptor: Dipeptidyl aminopeptidase-like protein 6, Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2
Authors:Kise, Y, Nureki, O.
Deposit date:2021-03-01
Release date:2021-10-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of gating modulation of Kv4 channel complexes.
Nature, 599, 2021
7E8H
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BU of 7e8h by Molmil
CryoEM structure of human Kv4.2-DPP6S-KChIP1 complex
Descriptor: Dipeptidyl aminopeptidase-like protein 6, Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 2
Authors:Kise, Y, Nureki, O.
Deposit date:2021-03-01
Release date:2021-10-13
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural basis of gating modulation of Kv4 channel complexes.
Nature, 599, 2021
7E87
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CryoEM structure of the human Kv4.2-DPP6S complex, transmembrane and intracellular region
Descriptor: Dipeptidyl aminopeptidase-like protein 6, Potassium voltage-gated channel subfamily D member 2
Authors:Kise, Y, Nureki, O.
Deposit date:2021-03-01
Release date:2021-10-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of gating modulation of Kv4 channel complexes.
Nature, 599, 2021
7E8B
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BU of 7e8b by Molmil
CryoEM structure of human Kv4.2-DPP6S complex
Descriptor: Dipeptidyl aminopeptidase-like protein 6, Potassium voltage-gated channel subfamily D member 2
Authors:Kise, Y, Nureki, O.
Deposit date:2021-03-01
Release date:2021-10-13
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of gating modulation of Kv4 channel complexes.
Nature, 599, 2021

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