PDB: 92800 resultsInfo pagesStatus searchChemie searchBIRD

---

2JND	3D NMR structure of ECD1 of mCRF-R2b in complex with Astressin Descriptor: ASTRESSIN, Corticotropin-releasing factor receptor 2 Authors: Grace, C.R.R, Perrin, M.H, Jozsef, G, DiGruccio, M.R, Cantle, J.P, Rivier, J.E, Vale, W.W, Riek, R. Deposit date: 2007-01-08 Release date: 2007-03-13 Last modified: 2023-12-20 Method: SOLUTION NMR Cite: Structure of the N-terminal domain of a type B1 G protein-coupled receptor in complex with a peptide ligand Proc.Natl.Acad.Sci.USA, 104, 2007
6TB7	Crystal structure of the ADP-binding domain of the NAD+ riboswitch with Adenosine monophosphate (AMP) Descriptor: ADENOSINE MONOPHOSPHATE, BROMIDE ION, MAGNESIUM ION, ... Authors: Huang, L, Lilley, D.M.J. Deposit date: 2019-11-01 Release date: 2020-09-30 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Structure and ligand binding of the ADP-binding domain of the NAD + riboswitch. Rna, 26, 2020
1P7K	Crystal structure of an anti-ssDNA antigen-binding fragment (Fab) bound to 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid (HEPES) Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Schuermann, J.P, Henzl, M.T, Deutscher, S.L, Tanner, J.J. Deposit date: 2003-05-02 Release date: 2004-05-11 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structure of an anti-DNA fab complexed with a non-DNA ligand provides insights into cross-reactivity and molecular mimicry. Proteins, 57, 2004
6TF2	Crystal structure of the ADP-binding domain of the NAD+ riboswitch with Adenosine 5-triphosphate (ATP) Descriptor: ADENOSINE-5'-TRIPHOSPHATE, BROMIDE ION, Chains: A, ... Authors: Huang, L, Lilley, D.M.J. Deposit date: 2019-11-12 Release date: 2020-09-23 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structure and ligand binding of the ADP-binding domain of the NAD+ riboswitch. Rna, 26, 2020
2W29	Gly102Thr mutant of Rv3291c Descriptor: PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Authors: Shrivastava, T, Dey, S, Ravishankar, R. Deposit date: 2008-10-25 Release date: 2009-11-17 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (4.1 Å) Cite: Ligand-Induced Structural Transitions, Mutational Analysis, and 'Open' Quaternary Structure of the M. Tuberculosis Feast/Famine Regulatory Protein (Rv3291C). J.Mol.Biol., 392, 2009
5QJ0	CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS GENOTYPE 2A STRAIN JFH1 NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 6-[ethyl(methylsulfonyl)amino]-2-(4-fluorophenyl)-N-methyl-5-(3-{[1-(pyrimidin-2-yl)cyclopropyl]carbamoyl}phenyl)-1-benzofuran-3-carboxamide Descriptor: 6-[ethyl(methylsulfonyl)amino]-2-(4-fluorophenyl)-N-methyl-5-(3-{[1-(pyrimidin-2-yl)cyclopropyl]carbamoyl}phenyl)-1-benzofuran-3-carboxamide, GLYCEROL, NONAETHYLENE GLYCOL, ... Authors: Sheriff, S. Deposit date: 2018-08-13 Release date: 2018-11-21 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Structure-Property Basis for Solving Transporter-Mediated Efflux and Pan-Genotypic Inhibition in HCV NS5B Inhibitors. ACS Med Chem Lett, 9, 2018
6TFH	Crystal structure of the ADP-binding domain of the NAD+ riboswitch with Nicotinamide adenine dinucleotide, reduced (NADH); soaking with Manganese(II) (Mn2+) Descriptor: Chains: A, MANGANESE (II) ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... Authors: Huang, L, Lilley, D.M.J. Deposit date: 2019-11-14 Release date: 2020-09-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structure and ligand binding of the ADP-binding domain of the NAD+ riboswitch. Rna, 26, 2020
6O14	Crystal structure of the Aquifex aeolicus Wzt Carbohydrate Binding Domain Descriptor: ABC transporter, GLYCEROL Authors: Bi, Y, Zimmer, J. Deposit date: 2019-02-17 Release date: 2020-01-15 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure and Ligand-Binding Properties of the O Antigen ABC Transporter Carbohydrate-Binding Domain. Structure, 28, 2020
5JES	Human carbonic anhydrase II (V121T) complexed with benzo[d]thiazole-2-sulfonamide Descriptor: 1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION Authors: Fox, J.M, Kang, K, Sastry, M, Sherman, W, Sankaran, B, Zwart, P.H, Whitesides, G.M. Deposit date: 2016-04-18 Release date: 2017-01-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.205 Å) Cite: Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase. Angew. Chem. Int. Ed. Engl., 56, 2017
7A8Y	X-ray crystal structure of Aspartate alpha-decarboxylase in complex with D-Serine Descriptor: 1,2-ETHANEDIOL, Aspartate 1-decarboxylase, D-SERINE, ... Authors: Yorke, B.A, Raskar, T. Deposit date: 2020-08-31 Release date: 2021-10-06 Last modified: 2024-09-04 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structure and diffusive dynamics of aspartate alpha-decarboxylase (ADC) liganded with D-serine in aqueous solution. Phys Chem Chem Phys, 2022
2NV7	Crystal Structure of Estrogen Receptor Beta Complexed with WAY-555 Descriptor: 4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME, Estrogen receptor beta, Nuclear receptor coactivator 1 Authors: Mewshaw, R.E, Bowen, M.S, Harris, H.A, Xu, Z.B, Manas, E.S, Cohn, S.T, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-11-10 Release date: 2007-08-21 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.1 Å) Cite: ERbeta ligands. Part 5: synthesis and structure-activity relationships of a series of 4'-hydroxyphenyl-aryl-carbaldehyde oxime derivatives. Bioorg.Med.Chem.Lett., 17, 2007
6TFG	Crystal structure of the ADP-binding domain of the NAD+ riboswitch with Adenosine 3-phosphate 5-phosphosulfate (APPS) Descriptor: 3'-PHOSPHATE-ADENOSINE-5'-PHOSPHATE SULFATE, Chains: A, MAGNESIUM ION, ... Authors: Huang, L, Lilley, D.M.J. Deposit date: 2019-11-14 Release date: 2020-09-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structure and ligand binding of the ADP-binding domain of the NAD+ riboswitch. Rna, 26, 2020
4POW	Structure of the PBP NocT in complex with pyronopaline Descriptor: 1,2-ETHANEDIOL, 1-[(1S)-4-carbamimidamido-1-carboxybutyl]-5-oxo-D-proline, Nopaline-binding periplasmic protein Authors: Morera, S, Vigouroux, A. Deposit date: 2014-02-26 Release date: 2014-10-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Agrobacterium uses a unique ligand-binding mode for trapping opines and acquiring a competitive advantage in the niche construction on plant host. Plos Pathog., 10, 2014
6TF1	Crystal structure of the ADP-binding domain of the NAD+ riboswitch with Adenosine diphosphate (ADP) Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chains: A, MAGNESIUM ION, ... Authors: Huang, L, Lilley, D.M.J. Deposit date: 2019-11-12 Release date: 2020-09-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure and ligand binding of the ADP-binding domain of the NAD+ riboswitch. Rna, 26, 2020
7UWL	Structure of the IL-25-IL-17RB-IL-17RA ternary complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ... Authors: Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. Deposit date: 2022-05-03 Release date: 2022-07-27 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
7UWK	Structure of the higher-order IL-25-IL-17RB complex Descriptor: Interleukin-17 receptor B, Interleukin-25 Authors: Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. Deposit date: 2022-05-03 Release date: 2022-07-27 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
7UWJ	Structure of the homodimeric IL-25-IL-17RB binary complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor B, Interleukin-25 Authors: Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. Deposit date: 2022-05-03 Release date: 2022-07-27 Last modified: 2022-09-28 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
4N37	Structure of langerin CRD I313 D288 complexed with Me-Man Descriptor: C-type lectin domain family 4 member K, CALCIUM ION, methyl alpha-D-mannopyranoside Authors: Feinberg, H, Rowntree, T.J.W, Tan, S.L.W, Drickamer, K, Weis, W.I, Taylor, M.E. Deposit date: 2013-10-06 Release date: 2013-11-20 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Common polymorphisms in human langerin change specificity for glycan ligands. J.Biol.Chem., 288, 2013
2O5R	Crystal structure of Glutamyl-tRNA synthetase 1 (EC 6.1.1.17) (Glutamate-tRNA ligase 1) (GluRS 1) (TM1351) from Thermotoga maritima at 2.5 A resolution Descriptor: CHLORIDE ION, GLYCEROL, Glutamyl-tRNA synthetase 1 Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2006-12-06 Release date: 2006-12-19 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Crystal structure of Glutamyl-tRNA synthetase 1 (EC 6.1.1.17) (Glutamate-tRNA ligase 1) (GluRS 1) (TM1351) from Thermotoga maritima at 2.5 A resolution To be published
5JEH	Human carbonic anhydrase II (L198A) complexed with benzo[d]thiazole-2-sulfonamide Descriptor: 1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION Authors: Fox, J.M, Kang, K, Sastry, M, Sherman, W, Sankaran, B, Zwart, P.H, Whitesides, G.M. Deposit date: 2016-04-18 Release date: 2017-01-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.13 Å) Cite: Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase. Angew. Chem. Int. Ed. Engl., 56, 2017
5DPF	Thermolysin in complex with inhibitor. Descriptor: CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ... Authors: Krimmer, S.G, Heine, A, Klebe, G. Deposit date: 2015-09-12 Release date: 2015-10-28 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Thermodynamics of protein-ligand interactions as a reference for computational analysis: how to assess accuracy, reliability and relevance of experimental data. J. Comput. Aided Mol. Des., 29, 2015
4A83	Crystal Structure of Major Birch Pollen Allergen Bet v 1 a in complex with deoxycholate. Descriptor: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, MAJOR POLLEN ALLERGEN BET V 1-A, ... Authors: Kofler, S, Brandstetter, H. Deposit date: 2011-11-18 Release date: 2012-05-30 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Crystallographically Mapped Ligand Binding Differs in High and Low Ige Binding Isoforms of Birch Pollen Allergen Bet V 1. J.Mol.Biol., 422, 2012
5PZM	CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 3-[2-(4-FLUOROPHENYL)-3-(METHYLCARBAMOYL)-1-BENZOFURAN-5-YL]BENZOIC ACID Descriptor: (2E)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7-dihydro-5H-indolo[1,2-d][1,4]benzodiazepin-10-yl)carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic acid, 3-[2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-5-yl]benzoic acid, GLYCEROL, ... Authors: Sheriff, S. Deposit date: 2017-02-27 Release date: 2017-05-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies. J. Med. Chem., 60, 2017
5DDB	Menin in complex with MI-319 Descriptor: 4-{4-[5-(difluoromethyl)-1,3,4-thiadiazol-2-yl]piperazin-1-yl}-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidine, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... Authors: Pollock, J, Dmitry, B, Cierpicki, T, Grembecka, J. Deposit date: 2015-08-24 Release date: 2015-09-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein-Ligand Complexes. J.Med.Chem., 58, 2015
3B1M	Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator Cerco-A Descriptor: (9aS)-8-acetyl-N-[(2-ethylnaphthalen-1-yl)methyl]-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-carboxamide, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Authors: Matsui, Y, Hiroyuki, H. Deposit date: 2011-07-05 Release date: 2011-08-24 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Pharmacology and in Vitro Profiling of a Novel Peroxisome Proliferator-Activated Receptor gamma Ligand, Cerco-A Biol.Pharm.Bull., 34, 2011

<312313314315316317318319320321322323324325326327>