2NV7

Crystal Structure of Estrogen Receptor Beta Complexed with WAY-555

Summary for 2NV7

Entry DOI	10.2210/pdb2nv7/pdb
Descriptor	Estrogen receptor beta, Nuclear receptor coactivator 1, 4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME, ... (4 entities in total)
Functional Keywords	estrogen receptor, estrogen receptor beta, er-beta, er, estrogen, nuclear receptor, transcription factor, agonist, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, transcription
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: Q92731 Nucleus (By similarity): Q15788
Total number of polymer chains	4
Total formula weight	56683.31
Authors	Mewshaw, R.E.,Bowen, M.S.,Harris, H.A.,Xu, Z.B.,Manas, E.S.,Cohn, S.T.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2006-11-10, release date: 2007-08-21, Last modification date: 2024-04-03)
Primary citation	Mewshaw, R.E.,Bowen, S.M.,Harris, H.A.,Xu, Z.B.,Manas, E.S.,Cohn, S.T. ERbeta ligands. Part 5: synthesis and structure-activity relationships of a series of 4'-hydroxyphenyl-aryl-carbaldehyde oxime derivatives. Bioorg.Med.Chem.Lett., 17:902-906, 2007 Cited by PubMed: 17188490 DOI: 10.1016/j.bmcl.2006.11.066 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation