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6K06
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Crystal structure of Importin-alpha and phosphomimetic GM130
Descriptor: Importin subunit alpha-1, Peptide from Golgin subfamily A member 2
Authors:Chang, C.-C, Chen, C.-J, Pien, Y.-C, Tsai, S.-Y, Hsia, K.-C.
Deposit date:2019-05-05
Release date:2019-10-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-alpha.
Nat Commun, 10, 2019
6IWA
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BU of 6iwa by Molmil
Crystal structure of Importin-alpha and phosphoserine GM130
Descriptor: Importin subunit alpha-1, PHOSPHOSERINE GM130
Authors:Chang, C.-C, Chen, C.-J, Pien, Y.-C, Tsai, S.-Y, Hsia, K.-C.
Deposit date:2018-12-05
Release date:2019-10-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-alpha.
Nat Commun, 10, 2019
4ZDU
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BU of 4zdu by Molmil
Crystal structure of importin-alpha bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein
Descriptor: Importin subunit alpha-1, Peptide from Nucleoprotein
Authors:Nakada, R, Hirano, H, Matsuura, Y.
Deposit date:2015-04-19
Release date:2015-10-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of importin-alpha bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein
Sci Rep, 5, 2015
6IU7
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BU of 6iu7 by Molmil
Crystal structure of importin-alpha1 bound to the 53BP1 nuclear localization signal (wild-type)
Descriptor: Importin subunit alpha-1, Peptide from TP53-binding protein 1
Authors:Matsuura, Y.
Deposit date:2018-11-27
Release date:2019-01-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and biochemical characterization of the recognition of the 53BP1 nuclear localization signal by importin-alpha.
Biochem. Biophys. Res. Commun., 510, 2019
2P8Q
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BU of 2p8q by Molmil
Crystal Structure of human Importin beta bound to the Snurportin1 IBB-domain
Descriptor: Importin beta-1 subunit, Snurportin-1
Authors:Mitrousis, G, Cingolani, G.
Deposit date:2007-03-22
Release date:2008-01-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}.
J.Biol.Chem., 283, 2008
4XRK
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BU of 4xrk by Molmil
Crystal Structure of Importin Beta in a Polyethylene Glycol Condition
Descriptor: Importin Beta
Authors:Tauchert, M.J, Neumann, P, Ficner, R, Dickmanns, A.
Deposit date:2015-01-21
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Impact of the crystallization condition on importin-beta conformation.
Acta Crystallogr D Struct Biol, 72, 2016
2Q5D
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BU of 2q5d by Molmil
Crystal Structure of Human Importin Beta bound to the Snurportin1 IBB-domain second crystal form
Descriptor: Importin beta-1 subunit, Snurportin-1
Authors:Mitrousis, G, Cingolani, G.
Deposit date:2007-05-31
Release date:2008-01-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Molecular Basis for the Recognition of Snurportin 1 by Importin {beta}.
J.Biol.Chem., 283, 2008
1IQ1
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BU of 1iq1 by Molmil
CRYSTAL STRUCTURE OF THE IMPORTIN-ALPHA(44-54)-IMPORTIN-ALPHA(70-529) COMPLEX
Descriptor: IMPORTIN ALPHA-2 SUBUNIT
Authors:Catimel, B, Teh, T, Fontes, M.R.M, Jennings, I.G, Kobe, B.
Deposit date:2001-05-28
Release date:2001-11-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Biophysical characterization of interactions involving importin-alpha during nuclear import.
J.Biol.Chem., 276, 2001
7UNK
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BU of 7unk by Molmil
Structure of Importin-4 bound to the H3-H4-ASF1 histone-histone chaperone complex
Descriptor: Histone H3, Histone H4, Histone chaperone, ...
Authors:Bernardes, N.E, Chook, Y.M, Fung, H.Y.J, Chen, Z, Li, Y.
Deposit date:2022-04-11
Release date:2022-09-21
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex.
Proc.Natl.Acad.Sci.USA, 119, 2022
4OIH
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BU of 4oih by Molmil
Importin Alpha in Complex with the Bipartite NLS of Prp20
Descriptor: Guanine nucleotide exchange factor SRM1, Importin subunit alpha-1
Authors:Roman, N, Christie, M, Swarbrick, C.M.D, Kobe, B, Forwood, J.K.
Deposit date:2014-01-19
Release date:2014-02-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Characterisation of the Nuclear Import Receptor Importin Alpha in Complex with the Bipartite NLS of Prp20
Plos One, 8, 2013
1PJN
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BU of 1pjn by Molmil
Mouse Importin alpha-bipartite NLS N1N2 from Xenopus laevis phosphoprotein Complex
Descriptor: Histone-binding protein N1/N2, Importin alpha-2 subunit
Authors:Fontes, M.R.M, Teh, T, Jans, D, Brinkworth, R.I, Kobe, B.
Deposit date:2003-06-03
Release date:2003-08-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha
J.Biol.Chem., 278, 2003
1Q1T
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BU of 1q1t by Molmil
Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex
Descriptor: Importin alpha-2 subunit, Large T antigen
Authors:Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B.
Deposit date:2003-07-22
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
1Q1S
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BU of 1q1s by Molmil
Mouse Importin alpha- phosphorylated SV40 CN peptide complex
Descriptor: Importin alpha-2 subunit, Large T antigen
Authors:Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B.
Deposit date:2003-07-22
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
5K9S
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BU of 5k9s by Molmil
Importin-alpha in complex with HNF1-beta peptide
Descriptor: HNF1 beta A splice variant 2, Importin subunit alpha-1
Authors:Wiedmann, M.M, Aibara, S, Spring, D.R, Stewart, M, Brenton, J.
Deposit date:2016-06-01
Release date:2016-11-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Importin-alpha in complex with HNF1-beta peptide
To Be Published
3FEY
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BU of 3fey by Molmil
Crystal structure of the CBC-importin alpha complex.
Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2
Authors:Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A.
Deposit date:2008-12-01
Release date:2009-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
3FEX
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BU of 3fex by Molmil
Crystal structure of the CBC-importin alpha complex.
Descriptor: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2
Authors:Dias, S.M.G, Ambrosio, A.L.B, Cerione, R.A.
Deposit date:2008-12-01
Release date:2009-08-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.549 Å)
Cite:The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
1F59
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BU of 1f59 by Molmil
IMPORTIN-BETA-FXFG NUCLEOPORIN COMPLEX
Descriptor: FXFG NUCLEOPORIN REPEATS, IMPORTIN BETA-1
Authors:Bayliss, R, Littlewood, T, Stewart, M.
Deposit date:2000-06-13
Release date:2000-08-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking.
Cell(Cambridge,Mass.), 102, 2000
7TMX
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BU of 7tmx by Molmil
Structure of Mouse Importin alpha NEIL1 NLS Peptide Complex
Descriptor: Importin subunit alpha-1, Nuclear Localization Signal from Endonuclease 8-like 1
Authors:Moraes, I.R, de Oliveira, H.C, Fontes, M.R.M.
Deposit date:2022-01-20
Release date:2023-08-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of nuclear transport for NEIL DNA glycosylases mediated by importin-alpha.
Biochim Biophys Acta Proteins Proteom, 1872, 2023
7TMY
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BU of 7tmy by Molmil
Structure of Mouse Importin alpha NEIL3 NLS Peptide Complex
Descriptor: Importin subunit alpha-1, Nuclear Localization Signal from Endonuclease 8-like 3
Authors:Moraes, I.R, de Oliveira, H.C, Fontes, M.R.M.
Deposit date:2022-01-20
Release date:2023-08-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural basis of nuclear transport for NEIL DNA glycosylases mediated by importin-alpha.
Biochim Biophys Acta Proteins Proteom, 1872, 2023
8DYO
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BU of 8dyo by Molmil
Cryo-EM structure of Importin-4 bound to RanGTP
Descriptor: GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Importin-4, ...
Authors:Bernardes, N.E, Fung, H.Y.J, Li, Y, Chen, Z, Chook, Y.M.
Deposit date:2022-08-04
Release date:2022-09-21
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex.
Proc.Natl.Acad.Sci.USA, 119, 2022
8HKW
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BU of 8hkw by Molmil
Crystal structure of importin-alpha3 bound to the 53BP1 nuclear localization signal
Descriptor: Importin subunit alpha-3, Peptide from TP53-binding protein 1
Authors:Matsuura, Y.
Deposit date:2022-11-28
Release date:2022-12-21
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic data of an importin-alpha 3 dimer in which the two protomers are bridged by a bipartite nuclear localization signal.
Data Brief, 47, 2023
3ZJY
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BU of 3zjy by Molmil
Crystal Structure of Importin 13 - RanGTP - eIF1A complex
Descriptor: EUKARYOTIC TRANSLATION INITIATION FACTOR 1A, X-CHROMOSOMAL, GTP-BINDING NUCLEAR PROTEIN RAN, ...
Authors:Gruenwald, M, Lazzaretti, D, Bono, F.
Deposit date:2013-01-21
Release date:2013-04-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural Basis for the Nuclear Export Activity of Importin13.
Embo J., 32, 2013
4RXH
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BU of 4rxh by Molmil
Crystal Structure of Importin-alpha from Neurospora crassa complexed with SV40NLS
Descriptor: Importin subunit alpha, Large T antigen
Authors:Bernardes, N.E, Takeda, A.A.S, Fontes, M.R.M.
Deposit date:2014-12-11
Release date:2015-07-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7553 Å)
Cite:Structure of Importin-alpha from a Filamentous Fungus in Complex with a Classical Nuclear Localization Signal.
Plos One, 10, 2015
8SUD
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BU of 8sud by Molmil
JC Polyomavirus LTA NLS bound to importin alpha 2
Descriptor: Importin subunit alpha-1, Large T antigen
Authors:Cross, E.M, Forwood, J.K, Alvisi, G.
Deposit date:2023-05-12
Release date:2024-02-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
8TUU
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BU of 8tuu by Molmil
MW Polyomavirus LTA bipartite NLS bound to importin alpha 2
Descriptor: Importin subunit alpha-1, Large T-antigen
Authors:Cross, E.M, Forwood, J.K, Alvisi, G.
Deposit date:2023-08-17
Release date:2024-02-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024

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