6MAF
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![BU of 6maf by Molmil](/molmil-images/mine/6maf) | native BbvCI A2B2 tetramer at low resolution | Descriptor: | BbvCI endonuclease subunit 1, BbvCI endonuclease subunit 2 | Authors: | Shen, B.W, Stoddard, B.L. | Deposit date: | 2018-08-27 | Release date: | 2018-11-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.79 Å) | Cite: | Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI. Nucleic Acids Res., 47, 2019
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3RPZ
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![BU of 3rpz by Molmil](/molmil-images/mine/3rpz) | Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis co-crystallized with ATP/Mg2+ and soaked with NADPH | Descriptor: | ADENOSINE MONOPHOSPHATE, ADP/ATP-dependent NAD(P)H-hydrate dehydratase, BETA-6-HYDROXY-1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE, ... | Authors: | Shumilin, I.A, Cymborowski, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-04-27 | Release date: | 2011-07-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Identification of unknown protein function using metabolite cocktail screening. Structure, 20, 2012
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7AEU
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![BU of 7aeu by Molmil](/molmil-images/mine/7aeu) | |
7AET
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![BU of 7aet by Molmil](/molmil-images/mine/7aet) | |
7AEV
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![BU of 7aev by Molmil](/molmil-images/mine/7aev) | |
6V2G
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![BU of 6v2g by Molmil](/molmil-images/mine/6v2g) | |
5Y2P
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![BU of 5y2p by Molmil](/molmil-images/mine/5y2p) | |
5Y9R
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![BU of 5y9r by Molmil](/molmil-images/mine/5y9r) | |
8UUE
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![BU of 8uue by Molmil](/molmil-images/mine/8uue) | |
6V2C
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![BU of 6v2c by Molmil](/molmil-images/mine/6v2c) | |
5MEY
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![BU of 5mey by Molmil](/molmil-images/mine/5mey) | Crystal structure of Smad4-MH1 bound to the GGCGC site. | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Kaczmarska, Z, Freier, R, Marquez, J.A, Macias, M.J. | Deposit date: | 2016-11-16 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun, 8, 2017
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7AZ5
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![BU of 7az5 by Molmil](/molmil-images/mine/7az5) | DNA polymerase sliding clamp from Escherichia coli with peptide 47 bound | Descriptor: | Beta sliding clamp, DI(HYDROXYETHYL)ETHER, Peptide 47, ... | Authors: | Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. | Deposit date: | 2020-11-16 | Release date: | 2021-12-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
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4R3U
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![BU of 4r3u by Molmil](/molmil-images/mine/4r3u) | Crystal structure of 2-Hydroxyisobutyryl-CoA Mutase | Descriptor: | 2-hydroxyisobutyryl-CoA mutase large subunit, 2-hydroxyisobutyryl-CoA mutase small subunit, 3-HYDROXYBUTANOYL-COENZYME A, ... | Authors: | Zahn, M, Kurteva-Yaneva, N, Rohwerder, T, Straeter, N. | Deposit date: | 2014-08-18 | Release date: | 2015-03-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of the stereospecificity of bacterial B12-dependent 2-hydroxyisobutyryl-CoA mutase. J.Biol.Chem., 290, 2015
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3RTQ
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![BU of 3rtq by Molmil](/molmil-images/mine/3rtq) | Structure of the mouse CD1d-HS44-iNKT TCR complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | Authors: | Yu, E.D, Zajonc, D.M. | Deposit date: | 2011-05-03 | Release date: | 2012-02-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and functional characterization of a novel nonglycosidic type I NKT agonist with immunomodulatory properties. J.Immunol., 188, 2012
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5LYN
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![BU of 5lyn by Molmil](/molmil-images/mine/5lyn) | Structure of the Tpr Domain of Sgt2 in complex with yeast Ssa1 peptide fragment | Descriptor: | PRO-THR-VAL-GLU-GLU-VAL-ASP, Small glutamine-rich tetratricopeptide repeat-containing protein 2, ZINC ION | Authors: | Krysztofinska, E.M, Evans, N.J, Thapaliya, A, Murray, J.W, Morgan, R.M.L, Martinez-Lumbreras, S, Isaacson, R.L. | Deposit date: | 2016-09-28 | Release date: | 2017-10-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp. Front Mol Biosci, 4, 2017
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4GTE
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![BU of 4gte by Molmil](/molmil-images/mine/4gte) | T. Maritima FDTS (E144R mutant) with FAD and Folate | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, N-({4-[(6aR)-3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]phenyl}carbonyl)-L-glutamic acid, Thymidylate synthase thyX | Authors: | Mathews, I.I, Lesley, S.A, Kohen, A, Prabhakar, A. | Deposit date: | 2012-08-28 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Folate binding site of flavin-dependent thymidylate synthase. Proc.Natl.Acad.Sci.USA, 109, 2012
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4GTA
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![BU of 4gta by Molmil](/molmil-images/mine/4gta) | T. Maritima FDTS with FAD, dUMP, and Folinic Acid | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Mathews, I.I, Lesley, S.A, Kohen, A. | Deposit date: | 2012-08-28 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Folate binding site of flavin-dependent thymidylate synthase. Proc.Natl.Acad.Sci.USA, 109, 2012
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4E4H
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![BU of 4e4h by Molmil](/molmil-images/mine/4e4h) | Crystal structure of Histone Demethylase NO66 | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, FE (III) ION, ... | Authors: | Wu, M, Tao, Y, Zang, J. | Deposit date: | 2012-03-13 | Release date: | 2013-01-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | tructural Basis for Tetramerization-dependent Gene Repression by Histone Demethylase NO66 To be Published
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5F8A
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![BU of 5f8a by Molmil](/molmil-images/mine/5f8a) | Crystal structure of the ternary EcoRV-DNA-Lu complex with uncleaved DNA substrate. Lanthanide binding to EcoRV-DNA complex inhibits cleavage. | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*T)-3'), LUTETIUM (III) ION, ... | Authors: | Sangani, S.S, Kehr, A.D, Sinha, K, Rule, G.S, Jen-Jacobson, L. | Deposit date: | 2015-12-09 | Release date: | 2016-11-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Metal Ion Binding at the Catalytic Site Induces Widely Distributed Changes in a Sequence Specific Protein-DNA Complex. Biochemistry, 55, 2016
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5NM9
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![BU of 5nm9 by Molmil](/molmil-images/mine/5nm9) | Crystal structure of the placozoa Trichoplax adhaerens Smad4-MH1 bound to the GGCGC site. | Descriptor: | DNA (5'-D(P*AP*TP*GP*CP*GP*GP*GP*CP*GP*CP*GP*CP*CP*CP*GP*CP*AP*T)-3'), Mothers against decapentaplegic homolog, ZINC ION | Authors: | Kaczmarska, Z, Freier, R, Marquez, J.A, Macias, M.J. | Deposit date: | 2017-04-05 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun, 8, 2017
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3B04
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![BU of 3b04 by Molmil](/molmil-images/mine/3b04) | Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with oIPP. | Descriptor: | 1-deoxy-1-[(4aR)-4a-[(2R)-1-hydroxy-5-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}-3-methylidenepentan-2-yl]-7,8-dimethyl-2,4-dioxo-3,4,4a,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-5-O-phosphono-D-ribitol, Isopentenyl-diphosphate delta-isomerase, MAGNESIUM ION | Authors: | Unno, H, Nagai, T, Hemmi, H. | Deposit date: | 2011-06-03 | Release date: | 2011-11-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Covalent modification of reduced flavin mononucleotide in type-2 isopentenyl diphosphate isomerase by active-site-directed inhibitors. Proc.Natl.Acad.Sci.USA, 108, 2011
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5LU5
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![BU of 5lu5 by Molmil](/molmil-images/mine/5lu5) | A quantum half-site enzyme | Descriptor: | 7-O-phosphono-D-glycero-alpha-D-manno-heptopyranose, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Vivoli, M, Harmer, N.J, Pang, J. | Deposit date: | 2016-09-08 | Release date: | 2017-12-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A half-site multimeric enzyme achieves its cooperativity without conformational changes. Sci Rep, 7, 2017
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5LTZ
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![BU of 5ltz by Molmil](/molmil-images/mine/5ltz) | GmhA_mutant Q175E | Descriptor: | 1,2-ETHANEDIOL, D-ALTRO-HEPT-2-ULOSE 7-PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Vivoli, M, Harmer, N.J. | Deposit date: | 2016-09-07 | Release date: | 2017-12-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | A half-site multimeric enzyme achieves its cooperativity without conformational changes. Sci Rep, 7, 2017
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4P3H
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5MF0
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![BU of 5mf0 by Molmil](/molmil-images/mine/5mf0) | Crystal structure of Smad4-MH1 bound to the GGCCG site. | Descriptor: | CHLORIDE ION, DNA (5'-D(P*AP*CP*GP*GP*GP*CP*CP*GP*CP*GP*GP*CP*CP*CP*GP*T)-3'), MH1 domain of human Smad4, ... | Authors: | Kaczmarska, Z, Freier, R, Marquez, J.A, Macias, M.J. | Deposit date: | 2016-11-16 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun, 8, 2017
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