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5Y2P

Crystal Structure of Bacillus sp. TB-90 Urate Oxidase Improved by Humidity Control at 89% RH

Summary for 5Y2P
Entry DOI10.2210/pdb5y2p/pdb
DescriptorUric acid degradation bifunctional protein, 8-AZAXANTHINE, OXYGEN MOLECULE, ... (7 entities in total)
Functional Keywordsprotein engineering, oxidase, ph dependence, enzyme activation, flexibility, loop plasticity, oxidoreductase
Biological sourceBacillus sp. (strain TB-90)
Total number of polymer chains2
Total formula weight72305.97
Authors
Itoh, T.,Nishiya, Y. (deposition date: 2017-07-26, release date: 2018-08-08, Last modification date: 2023-11-22)
Primary citationHibi, T.,Itoh, T.,Fukada, H.,Kishimoto, T.,Nishiya, Y.
Conformational Flexibility of Plastic Interface Loop Allows Entropic Adaptation of Urate Oxidase to Environmental pH.
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

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